Bs0→η(′)η(′)B_s^0 \to \eta^{(\prime)} \eta^{(\prime)} decays in the pQCD approach

We calculate the CP averaged branching ratios and CP-violating asymmetries for $B_s^0 \to \eta \eta, \eta \eta^\prime$ and $\eta^\prime \eta^\prime$ decays in the perturbative QCD (pQCD) approach here. The pQCD predictions for the CP-averaged branching ratios are Br(B_s^0 \to \eta \eta) = \left (14.2^{+18.0}_{-7.5}) \times 10^{-6}, Br(B_s^0 \to \eta \eta^\prime)= \left (12.4 ^{+18.2}_{-7.0}) \times 10^{-6}, and Br(B_s^0 \to \eta^{\prime} \eta^{\prime}) = \left (9.2^{+15.3}_{-4.9}) \times 10^{-6}, which agree well with those obtained by employing the QCD factorization approach and also be consistent with available experimental upper limits. The gluonic contributions are small in size: less than 7% for $B_s \to \eta \eta$ and $\eta \eta^\prime$ decays, and around 18% for $B_s \to \eta' \eta'$ decay. The CP-violating asymmetries for three decays are very small: less than 3% in magnitude.Comment: 11 pages, 1 ps figure, Revte

Frozen water waves over rough topographical bottoms

The propagation of surface water waves over rough topographical bottoms is investigated by the multiple scattering theory. It is shown that the waves can be localized spatially through the process of multiple scattering and wave interference, a peculiar wave phenomenon which has been previously discussed for frozen light in optical systems (S. John, Nature {\bf 390}, 661, (1997)). We demonstrate that when frozen, the transmission of the waves falls off exponentially, and a cooperative behavior appears, fully supporting previous predictions. A phase diagram method is used to illustrate this distinct phase states in the wave propagation.Comment: 4 pages and 5 figure

Gravity waves over topographical bottoms: Comparison with the experiment

In this paper, the propagation of water surface waves over one-dimensional periodic and random bottoms is investigated by the transfer matrix method. For the periodic bottoms, the band structure is calculated, and the results are compared to the transmission results. When the bottoms are randomized, the Anderson localization phenomenon is observed. The theory has been applied to an existing experiment (Belzons, et al., J. Fluid Mech. {\bf 186}, 530 (1988)). In general, the results are compared favorably with the experimental observation.Comment: 15 pages, 7 figure

Spatiotemporal Fluctuation Induced Transition in a Tumor Model with Immune Surveillance

We report on a simple model of spatial extend anti-tumor system with a fluctuation in growth rate, which can undergo a nonequilibrium phase transition. Three states as excited, sub-excited and non-excited states of a tumor are defined to describe its growth. The multiplicative noise is found to be double-face: The positive effect on a non-excited tumor and the negative effect on an excited tumor.Comment: 8pages,5figure

Three-body recombination of ultra-cold atoms to a weakly bound ss level

We discuss three-body recombination of ultra-cold atoms to a weakly bound $s$ level. In this case, characterized by large and positive scattering length $a$ for pair interaction, we find a repulsive effective potential for three-body collisions, which strongly reduces the recombination probability and makes simple Jastrow-like approaches absolutely inadequate. In the zero temperature limit we obtain a universal relation, independent of the detailed shape of the interaction potential, for the (event) rate constant of three-body recombination: $\alpha_{\rm rec}=3.9\hbar a^4/m$, where $m$ is the atom mass.Comment: 10 pages, 3 Postscript figure

Charmless hadronic Bc→VA,AAB_c \to VA, AA decays in the perturbative QCD approach

In this work, we calculate the branching ratios (BRs) and the polarization fractions of sixty two charmless two-body $B_c$ meson decays into final states involving one vector and one axial-vector meson ($VA$) or two axial-vector mesons($AA$) within the framework of perturbative QCD (pQCD) approach systematically, where $A$ is either a $^3P_1$ or $^1P_1$ axial-vector meson. All considered decay channels can only occur through the annihilation topologies in the standard model. Based on the perturbative calculations and phenomenological analysis, we find the following results: (i) the CP-averaged BRs of the considered sixty two $B_c$ decays are in the range of $10^{-5}$ to $10^{-9}$; (ii) since the behavior for $^1P_1$ meson is much different from that of $^3P_1$ meson, the BRs of $B_c \to A(^1P_1) (V, A(^1P_1))$ decays are generally larger than that of $B_c \to A(^3P_1) (V, A(^3P_1))$ decays in the pQCD approach; (iii) many considered decays modes, such as $B_c\to a_1(1260)^+ \omega$, $b_1(1235) \rho$, etc, have sizable BRs within the reach of the LHCb experiments; (iv) the longitudinal polarization fractions of most considered decays are large and play the dominant role; (v) the pQCD predictions for several decays involving mixtures of $^3P_1$ and/or $^1P_1$ mesons are highly sensitive to the values of the mixing angles, which will be tested by the ongoing LHC and forthcoming Super-B experiments; (vi) the CP-violating asymmetries of these considered $B_c$ decays are absent in the standard model because only one type tree operator is involved.Comment: 31 pages, 1 figur

Histotripsy Erosion of Model Urinary Calculi

Background and Purpose: Histotripsy is a pulsed focused ultrasound technology in which initiation and control of acoustic cavitation allow for precise mechanical fractionation of tissues. The present study examines the feasibility of using histotripsy for erosion of urinary calculi. Materials and Methods: Histotripsy treatment was delivered from a 750-kHz transducer in the form of 5-cycle acoustic pulses at a 1-kHz pulse repetition frequency. Model stones were sonicated for 5 minutes at peak negative pressures (p-) of 10, 15, 19, 22, and 24-MPa. Resulting fragment sizes and comminution rates were assessed and compared with those achieved with a piezoelectric lithotripter (Wolf Piezolith 3000) operated at 2-Hz pulse repetition frequency and power level 17 (p- = 14-MPa). Results: Histotripsy eroded the surface of stones producing fine (<100--m) particulate debris in contrast to the progressive and incomplete subdivision of stones achieved with piezoelectric lithotripsy. The histotripsy erosion rate increased with increasing peak negative pressure from 10 to 19-MPa and then saturated, yielding an average rate of 87.9+/-12.8 mg/min at maximum treatment intensity. Piezoelectric lithotripsy achieved an average treatment rate of 110.7+/-27.4 mg/min. Conclusions: Histotripsy comminution of urinary calculi is a surface erosion phenomenon that is mechanistically distinct from conventional shockwave lithotripsy (SWL), producing only fine debris as opposed to coarse fragments. These characteristics suggest that histotripsy offers a potential adjunct to traditional SWL procedures, and synergistic interplay of the two modalities may lead to possible increases in both rate and degree of stone fragmentation.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90440/1/end-2E2010-2E0407.pd

A chemical screen identifies small molecules that regulate hepcidin expression

AbstractHepcidin, a peptide hormone produced in the liver, decreases intestinal iron absorption and macrophage iron release via effects on ferroportin. Bone morphogenic protein and Stat3 signaling regulate Hepcidin's transcription. Hepcidin is a potential drug target for patients with iron overload syndromes because its levels are inappropriately low in these individuals. To generate a tool for identifying small molecules that modulate Hepcidin expression, we stably transfected human hepatocytes (HepG2) cells with a reporter construct containing 2.7kb of the human Hepcidin promoter upstream of a firefly reporter gene. We used high throughput methods to screen 10,169 chemicals in duplicate for their effect on Hepcidin expression and cell viability. Regulators were identified as chemicals that caused a change >3 standard deviations above or >1 standard deviation below the mean of the other chemicals (z-score >3 or <1), while not adversely affecting cell viability, quantified by fluorescence assay. Following validation assays, we identified 16 chemicals in a broad range of functional classes that promote Hepcidin expression. All of the chemicals identified increased expression of bone morphogenic protein-dependent and/or Stat3-dependent genes, however none of them strongly increased phosphorylation of Smad1,5,8 or Stat3