Impacts of salinity parameterizations on temperature simulation over and in a hypersaline lake

In this paper, we introduced parameterizations of the salinity effects (on heat capacity, thermal conductivity, freezing point and saturated vapor pressure) in a lake scheme integrated in the Weather Research and Forecasting model coupled with the Community Land Model (WRF-CLM). This was done to improve temperature simulation over and in a saline lake and to test the contributions of salinity effects on various water properties via sensitivity experiments. The modified lake scheme consists of the lake module in the CLM model, which is the land component of the WRF-CLM model. The Great Salt Lake (GSL) in the USA was selected as the study area. The simulation was performed from September 3, 2001 to September 30, 2002. Our results show that the modified WRF-CLM model that includes the lake scheme considering salinity effects can reasonably simulate temperature over and in the GSL. This model had much greater accuracy than neglecting salinity effects, particularly in a very cold event when that effect alters the freezing point. The salinity effect on saturated vapor pressure can reduce latent heat flux over the lake and make it slightly warmer. The salinity effect on heat capacity can also make lake temperature prone to changes. However, the salinity effect on thermal conductivity was found insignificant in our simulations. © 2015, Chinese Society for Oceanology and Limnology, Science Press and Springer-Verlag Berlin Heidelberg

Thermal Responses of the Largest Freshwater Lake in the Tibetan Plateau and Its Nearby Saline Lake to Climate Change

There are thousands of lakes in the Tibetan Plateau (TP), and most are saline. However, little is known about the responses of TP lakes to climate change, especially saline ones. We investigated the thermal responses of the largest freshwater lake (Ngoring Lake) in the TP and its nearby small saline lake (Hajiang Salt Pond) to climate change using the improved lake scheme in the Community Land model (CLM4-LISSS), in which we primarily developed the salinity parameterizations previously evaluated in the Great Salt Lake in USA and further considered the effect of salinity on the temperature of the maximum density of saline water in the present study. The improved lake model with salinity parameterizations was first applied to a saline lake in the TP, where saline lakes make up the majority of water bodies. The CLM4-LISSS model could effectively simulate lake surface water temperature (LSWT), lake water temperature (LT) and ice thickness in Ngoring Lake. Additionally, the model including our salinity parameterizations significantly improved simulations of LSWT and LT in Hajiang Salt Pond, especially in winter. The LSWT of the two completely opposite lakes were warming in the simulations at a rate above 0.6 °C/decade. Meteorological forces were the main driving factor, with increasing downward longwave radiation, air temperature and air humidity, as well as weakening winds contributing to LSWT increase. Compared to a hypothetical shallow freshwater lake, the greater depth of Ngoring Lake made its surface warm faster, and salinity slightly accelerated the warming of Hajiang Salt Pond. Monthly mean LSWT differences between the two lakes were induced by salinity effects in cold periods and lake depth in the unfrozen period. In response to a warming climate, the LSWT in the ice-free Hajiang Salt Pond rapidly increased from January to April due to the warming climate, whereas the LSWT of Ngoring Lake increased faster in the first and last month of the ice-cover period due to later ice-on and earlier ice-off. This study will provide a useful tool for saline lakes in the TP and help deepen our knowledge about the responses of TP lakes, especially the saline lakes, to climate change, as well as response differences between freshwater and saline lakes and the reasons for these differences

Thermal Responses of the Largest Freshwater Lake in the Tibetan Plateau and Its Nearby Saline Lake to Climate Change

There are thousands of lakes in the Tibetan Plateau (TP), and most are saline. However, little is known about the responses of TP lakes to climate change, especially saline ones. We investigated the thermal responses of the largest freshwater lake (Ngoring Lake) in the TP and its nearby small saline lake (Hajiang Salt Pond) to climate change using the improved lake scheme in the Community Land model (CLM4-LISSS), in which we primarily developed the salinity parameterizations previously evaluated in the Great Salt Lake in USA and further considered the effect of salinity on the temperature of the maximum density of saline water in the present study. The improved lake model with salinity parameterizations was first applied to a saline lake in the TP, where saline lakes make up the majority of water bodies. The CLM4-LISSS model could effectively simulate lake surface water temperature (LSWT), lake water temperature (LT) and ice thickness in Ngoring Lake. Additionally, the model including our salinity parameterizations significantly improved simulations of LSWT and LT in Hajiang Salt Pond, especially in winter. The LSWT of the two completely opposite lakes were warming in the simulations at a rate above 0.6 °C/decade. Meteorological forces were the main driving factor, with increasing downward longwave radiation, air temperature and air humidity, as well as weakening winds contributing to LSWT increase. Compared to a hypothetical shallow freshwater lake, the greater depth of Ngoring Lake made its surface warm faster, and salinity slightly accelerated the warming of Hajiang Salt Pond. Monthly mean LSWT differences between the two lakes were induced by salinity effects in cold periods and lake depth in the unfrozen period. In response to a warming climate, the LSWT in the ice-free Hajiang Salt Pond rapidly increased from January to April due to the warming climate, whereas the LSWT of Ngoring Lake increased faster in the first and last month of the ice-cover period due to later ice-on and earlier ice-off. This study will provide a useful tool for saline lakes in the TP and help deepen our knowledge about the responses of TP lakes, especially the saline lakes, to climate change, as well as response differences between freshwater and saline lakes and the reasons for these differences

Genetic variants in ADAM33 are associated with airway inflammation and lung function in COPD

BACKGROUND: Genetic factors play a role in the development and severity of chronic obstructive pulmonary disease (COPD). The pathogenesis of COPD is a multifactorial process including an inflammatory cell profile. Recent studies revealed that single nucleotide polymorphisms (SNPs) within ADAM33 increased the susceptibility to COPD through changing the airway inflammatory process and lung function. METHODS: In this paper, we investigated associations of four polymorphisms (T1, T2, S2 and Q-1) of ADAM33 as well as their haplotypes with pulmonary function and airway inflammatory process in an East Asian population of patients with COPD. RESULTS: We found that T1, T2 and Q-1 were significantly associated with the changes of pulmonary function and components of cells in sputum of COPD, and T1 and Q-1 were significantly associated with cytokines and mediators of inflammation in airway of COPD in recessive models. 10 haplotypes were significantly associated with transfer factor of the lung for carbon monoxide in the disease state, 4 haplotypes were significantly associated with forced expiratory volume in one second, and other haplotypes were associated with airway inflammation. CONCLUSIONS: We confirmed for the first time that ADAM33 was involved in the pathogenesis of COPD by affecting airway inflammation and immune response in an East Asian population. Our results made the genetic background of COPD, a common and disabling disease, more apparent, which would supply genetic support for the study of the mechanism, classification and treatment for this disease. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1471-2466-14-173) contains supplementary material, which is available to authorized users