Fed by Books: The Circulation of Knowledge on Famine Plants in Ming-Qing China and Tokugawa Japan

This dissertation examines the dynamics of knowledge production and transcultural interactions in Ming-Qing China and Tokugawa Japan through the lens of famine plant manuals, i.e. writings that center on edible plants for use in times of food shortages. I argue that this genre was created out of the specific socioeconomic settings in pre-modern East Asia where food shortage proved to be a recurring theme, by a transnational epistemic community that shared interests in the natural world and concern for governmental affairs. My inquiry contributes to a deeper understanding of knowledge transformation and cultural interconnections: in the historical world of the Sinosphere where the learned elites shared a “high culture” written language and a rich literary tradition, most visibly embodied by the Sinitic script, concepts were expressed in words that did not cross borders via translation, but via their recontextualization and co-articulation in new socio-cultural and linguistic realities. Drawing evidence from administrative manuals, medical texts, local gazetteers and private notes, my findings suggest four main points concerning the shuffling classifications and hierarchies of famine food knowledge. First, despite that state intervention in famine relief was framed as Confucian signs of benevolent rule, famine plant manuals were created as responses to the limitations of the governments’ capacities to implement relief campaigns. Second, although derived from the bencao (materia medica) genre, famine plant manuals were largely devoid of medical interest and thus provided an alternative approach to natural history. The understanding of famine foods was shaped by the accessible natural resources and by epistemic interconnections within pre-modern East Asia, and such understanding also transformed the planning and utilization of the natural world, generating new knowledge about it. Third, although the increasing availability of textual knowledge about famine plants benefitted from the flourishing commercial publishing industry, the production and circulation of famine plant manuals featured a not-for-profit logic, underlined as a benevolent and charitable cause. Fourth, famine plant manuals negotiated between diverse knowledge fields, with statecraft and bencao in particular. On the one hand, they were tailored to governmental purposes and became absorbed in an all-encompassing famine relief discourses. On the other hand, they broadened the range of objects of investigation in the study of the natural world and suggested a de-medicalized approach

Relative Contributions of Inelastic Phonon Scattering and Elastic Phonon Scattering to Thermal Boundary Conductance across Solid Interfaces

The knowledge of inelastic phonon scattering is crucial for the understanding of thermal boundary conductance across solid interfaces. Several traditional theoretical models such as the acoustic mismatch model (AMM) and the diffuse mismatch model (DMM) assume that the elastic phonon scattering drives the thermal transport across the interface. But there are experiments indicating that the inelastic phonon scattering plays an important part in the interfacial thermal energy conduction as well. We use nonequilibrium molecular dynamics (NEMD) to predict the inelastic phonon conductance across Cu/Si interface. Temperature distribution across Cu/Si interface has been obtained from the simulation results, and a temperature drop across the interface is observed. The inelastic phonon scattering is compared to the elastic phonon scattering to demonstrate their relative contributions to the interfacial thermal conductance. The results show that at relatively high temperature, the inelastic phonon scattering can be comparable to elastic phonon scattering, providing an additional energy dissipation channel

Self-Asymmetric Invertible Network for Compression-Aware Image Rescaling

High-resolution (HR) images are usually downscaled to low-resolution (LR) ones for better display and afterward upscaled back to the original size to recover details. Recent work in image rescaling formulates downscaling and upscaling as a unified task and learns a bijective mapping between HR and LR via invertible networks. However, in real-world applications (e.g., social media), most images are compressed for transmission. Lossy compression will lead to irreversible information loss on LR images, hence damaging the inverse upscaling procedure and degrading the reconstruction accuracy. In this paper, we propose the Self-Asymmetric Invertible Network (SAIN) for compression-aware image rescaling. To tackle the distribution shift, we first develop an end-to-end asymmetric framework with two separate bijective mappings for high-quality and compressed LR images, respectively. Then, based on empirical analysis of this framework, we model the distribution of the lost information (including downscaling and compression) using isotropic Gaussian mixtures and propose the Enhanced Invertible Block to derive high-quality/compressed LR images in one forward pass. Besides, we design a set of losses to regularize the learned LR images and enhance the invertibility. Extensive experiments demonstrate the consistent improvements of SAIN across various image rescaling datasets in terms of both quantitative and qualitative evaluation under standard image compression formats (i.e., JPEG and WebP).Comment: Accepted by AAAI 2023. Code is available at https://github.com/yang-jin-hai/SAI

Serum IL-38 levels in patients with type 2 diabetes mellitus

Introduction: Interleukin 38 (IL-38) is a new member of the IL-1 family, and it has anti-inflammatory activity. However, its role in type 2 diabetes mellitus (T2DM) has not been reported. Material and methods: The study included 40 T2DM patients and 42 healthy control subjects. The anthropometric and biochemical measurements were performed using an automatic biochemical analyser, high-performance liquid chromatography, and electrochemiluminescence immunoassay. Circulating IL-38 levels were determined by enzyme-linked immunosorbent assay. Results: Serum IL-38 levels in T2DM patients were significantly lower than those in controls. Correlation analysis showed that serum IL-38 was negatively correlated with systolic blood pressure and interleukin 17 (IL-17). Conclusions: The results suggest that IL-38 may be a new biomarker of T2DM

Strain Induced One-Dimensional Landau-Level Quantization in Corrugated Graphene

Theoretical research has predicted that ripples of graphene generates effective gauge field on its low energy electronic structure and could lead to zero-energy flat bands, which are the analog of Landau levels in real magnetic fields. Here we demonstrate, using a combination of scanning tunneling microscopy and tight-binding approximation, that the zero-energy Landau levels with vanishing Fermi velocities will form when the effective pseudomagnetic flux per ripple is larger than the flux quantum. Our analysis indicates that the effective gauge field of the ripples results in zero-energy flat bands in one direction but not in another. The Fermi velocities in the perpendicular direction of the ripples are not renormalized at all. The condition to generate the ripples is also discussed according to classical thin-film elasticity theory.Comment: 4 figures, Phys. Rev.

Protective effect of Yiguanjian decoction against DNA damage on concanavalin A-induced liver injury mice model

AbstractObjectiveTo investigate the inhibitory effect of Yiguanjian decoction (YD) on DNA damage in Concanavalin A (Con A)-induced liver injury mice model and to explain the possible mechanism.MethodsTotally 120 male BALB/c mice were randomly divided into 6 groups, 20 mice each: normal group, model group, Bifendate group, YD low dose group, YD middle dose group and YD high dose group. Except normal group, liver injury model induced by Con A was established. While modeling, each mouse in YD group was given YD (0.4 mL/20 g per day) by intragastric administration (0.13 g YD for YD low dose group; 0.26 g for YD middle dose group; 0.52 g for YD high dose group). Bifendate group was given Bifendate (0.2 g·kg−1·d−1) by gavage. Normal group and model group were fed with same volume of physiological saline daily. After 8 weeks, the serum alanine transaminase (ALT) and aspartate transaminase (AST) were tested. The hematoxylin-eosin staining was used to evaluate the grade of liver inflammation and liver fibrosis stage. Hepatocellular DNA damage was detected by single cell gel electrophoresis technology. The protein expression of tumor necrosis factor-α (TNF-α), Bax and MutT Homolog 1 (MTH1) was detected by western blotting and enzyme linked immunosorbent assay. Bax mRNA and MTH1 mRNA were detected by Real-time Polymerase Chain Reaction (PCR).ResultsYD can improve the degree of liver inflammation and fibrosis in the liver of chronic hepatitis mice, the dose effect relationship is remarkable (P < 0.05). YD can reduce liver cell DNA damage. The difference between YD middle dose group and model group was statistically significant (P < 0.05). YD middle dose group had decreased the protein expression of TNF-α in the mice liver of immunological liver injury (P < 0.05). YD can increase the protein expression of Bax (P < 0.05). Compared with normal group, the protein expression of MTH1 was decreased (P < 0.05), but there was no statistical significance between YD group and model group (P > 0.05). YD can increase the mRNA expression of Bax and MTH1 (both P < 0.05).ConclusionYD can effectively inhibit the DNA damage in immunological liver injury mice, the mechanism may be that it can decrease the TNF-α and increase the Bax and MTH1 expression

Tomato short internodes and pedicels encode an LRR receptor-like serine/threonine-protein kinase ERECTA regulating stem elongation through modulating gibberellin metabolism

Plant height is an important agronomic trait. Dwarf varieties present several advantages, such as lodging resistance, increased yield, and suitability for mechanized harvesting, which are crucial for crop improvement. However, limited research is available on dwarf tomato varieties suitable for production. In this study, we report a novel short internode mutant named “short internode and pedicel (sip)” in tomato, which exhibits marked internode and pedicel shortening due to suppressed cell elongation. This mutant plant has a compact plant structure and compact inflorescence, and has been demonstrated to produce more fruits, resulting in a higher harvest index. Genetic analysis revealed that this phenotype is controlled by a single recessive gene, SlSIP. BSA analysis and KASP genotyping indicated that ERECTA (ER) is the possible candidate gene for SlSIP, which encodes a leucine-rich receptor-like kinase. Additionally, we obtained an ER functional loss mutant using the CRISPR/Cas9 gene-editing technology. The 401st base A of ER is substituted with T in sip, resulting in a change in the 134th amino acid from asparagine (N) to isoleucine (I). Molecular dynamics(MD) simulations showed that this mutation site is located in the extracellular LRR domain and alters nearby ionic bonds, leading to a change in the spatial structure of this site. Transcriptome analysis indicated that the genes that were differentially expressed between sip and wild-type (WT) plants were enriched in the gibberellin metabolic pathway. We found that GA3 and GA4 decreased in the sip mutant, and exogenous GA3 restored the sip to the height of the WT plant. These findings reveal that SlSIP in tomatoes regulates stem elongation by regulating gibberellin metabolism. These results provide new insights into the mechanisms of tomato dwarfing and germplasm resources for breeding dwarfing tomatoes

Physiological dynamics as indicators of plant response to manganese binary effect

IntroductionHeavy metals negatively affect plant physiology. However, plants can reduce their toxicity through physiological responses. Broussonetia papyrifera is a suitable candidate tree for carrying out the phytoremediation of manganese (Mn)-contaminated soil.MethodsConsidering that Mn stress typically exerts a binary effect on plants, to reveal the dynamic characteristics of the physiological indexes of B. papyrifera to Mn stress, we conducted pot experiments with six different Mn concentrations (0, 0.25, 0.5, 1, 2, and 5 mmol/L) for 60 days. In addition to the chlorophyll content, malondialdehyde (MDA), proline (PRO), soluble sugar, superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), the absorption and transfer characteristics of Mn, and root structure were also measured.ResultsPhytoremedial potential parameters such as the bioconcentration factor (BCF) and translocation factor (TF) displayed an increasing trend with the increase of Mn concentration. At lower Mn concentrations (&lt;0.5 mmol/L), the TF value was &lt;1 but crossed 1 when the Mn concentration exceeded 100 mmol/L. The Mn distribution in various tissues was in the following order: leaf &gt; stem &gt; root. The root structure analysis revealed that low-level concentrations of Mn (1 mmol/L) promoted root development. Mn concentration and stress duration had significant effects on all measured physiological indexes, and except soluble sugar, Mn concentration and stress time displayed a significant interaction on the physiological indexes.DiscussionOur study demonstrates that the physiological indexes of B. papyrifera display dynamic characteristics under Mn stress. Thus, during the monitoring process of Mn stress, it appears to be necessary to appropriately select sampling parts according to Mn concentration

Anomalous extensive landfast sea ice in the vicinity of Inexpressible Island, Antarctica

On 10 December 2017, a Chinese research vessel R/V Xuelong encountered an extensive area of landfast ice offshore Inexpressible Island (Antarctica) near the location where the fifth Chinese Antarctic research station is to be built. Using multi-source satellite images and weather data, we analyzed the ice conditions during the event season and reconstructed the development of landfast ice. Two stages in late September and early October were identified as contributing to the final ice extent. These two events are highly related to local- and large-scale weather conditions. Satellite images from 2003 to 2017 showed that four in fifteen years experienced severe landfast ice conditions, suggesting that it is not a rare phenomenon

Monitoring the Amery Ice Shelf front during 2004−2012 using ENVISAT ASAR data

The Amery Ice Shelf is the largest ice shelf in East Antarctica. It drains continental ice from an area of more than one million square kilometres through a section of coastline that represents approximately 2% of the total circumference of the Antarctic continent. In this study, we used a time series of ENVISAT ASAR images from 2004–2012 and flow lines derived from surface velocity data to monitor the changes in 12 tributaries of the Amery Ice Shelf front. The results show that the Amery Ice Shelf has been expanding and that the rates of expansion differ across the shelf. The highest average annual rate of advance from 2004–2012 was 3.36 m∙d-1 and the lowest rate was 1.65 m∙d-1. The rates in 2009 and 2010 were generally lower than those in other years. There was a low correlation between the rate of expansion and the atmospheric temperature recorded at a nearby research station, however the mechanism of the relationship was complex. This study shows that the expansion of the Amery Ice Shelf is slowing down, reflecting a changing trend in climate and ice conditions in East Antarctica