Cellular functions of NSF: Not just SNAPs and SNAREs

AbstractN-ethylmaleimide sensitive factor (NSF) is an ATPases associated with various cellular activities protein (AAA), broadly required for intracellular membrane fusion. NSF functions as a SNAP receptor (SNARE) chaperone which binds, through soluble NSF attachment proteins (SNAPs), to SNARE complexes and utilizes the energy of ATP hydrolysis to disassemble them thus facilitating SNARE recycling. While this is a major function of NSF, it does seem to interact with other proteins, such as the AMPA receptor subunit, GluR2, and β2-AR and is thought to affect their trafficking patterns. New data suggest that NSF may be regulated by transient post-translational modifications such as phosphorylation and nitrosylation. These new aspects of NSF function as well as its role in SNARE complex dynamics will be discussed

Is cloud computing the digital solution to the future of banking?

Acknowledgment: We express our thanks to the editors and anonymous referees for their constructive comments and suggestions, which have helped us significantly improve this paper. We have benefitted from discussions with colleagues and participants of different seminars/workshops in China and the UK. All remaining errors are our own. This research is financially supported by the Natural Science Foundation of China (72173036, 71973148) and the Chinese National Funding of Social Sciences (19CJY065).Peer reviewedPublisher PD

The impact of environmental, social, and governance, board diversity and firm size on the sustainable development goals of registered firm in China

Recently, sustainability practices have become a global requirement to attain the high-performance goals of the organizations and capture the focus of regulators and recent researchers. Therefore, the present article aim is to investigate the board diversity (percentage of women directors, percentage of nonexecutive directors and board member nationality) and firm size (logarithm of total assets) on the sustainability practices (expenditures on environmental sustainability) of the top ten registered firms in China. The researchers have adopted the secondary source of data collection and extracted the data from the financial statements of the adopted firms from 2005 to 2019. Additionally, the researchers used a fixed-effect model (FEM) and a robust standard error model to investigate the relationship between the two concepts. There were positive correlations between firm size (logarithmic total assets) and board diversity (percentage of women directors, percentage of non-executive directors, and board member nationality) and China’s top ten registered firms’ sustainability practises (expenditures on environmental sustainability). This research provides help to the policymakers while formulating strategies and policies related to the adoption of sustainability practices

Preparation of Mesoporous V2O5@TiO2 Composites with Enhanced Photoactivity for Gaseous Benzene Degradation

AbstractMesoporous V2O5@TiO2 composites were fabricated by an ultrasonic method with V2O5 sol as the guest precursor. The prepared materials were characterized by powder X-ray diffraction, field emission-scanning electron microscopy, transmission electron microscope, X-ray photoelectron spectroscopy, UV-Vis spectroscopy and nitrogen sorption analysis. The results indicated that V2O5 nanoparticles dispersed well on/into the porous structure of TiO2 matrix. The composites presented typical IUPAC IV isotherms with type H2 hysteresis loops, revealing the mesoporous structure. It was observed that V2O5 loading led to red shift of the absorption edge to 540nm and reduced the band gap < 3.0eV. The V2O5@TiO2 composites with V/Ti molar ratio of 0.1 exhibited outstanding degradation efficiency of gaseous benzene

A Swarm-based Dynamic Evacuation Simulation Model Under the Background of Secondary Disasters

AbstractDue to the occurrence of secondary disasters in disaster relief, a swarm-based dynamic disaster evacuation simulation model is established to settle the practical difficulties of reducing efficiency in evacuation. And much better simulation results have been achieved than static plans or disorganized autonomous escape scheme. Simulation results show that “to changing the status quo” dynamic evacuation plan is much better than “maintaining the status quo,” the static and self-evacuation plan or autonomous escape behavior for emergency evacuation, especially those with secondary disasters