225 research outputs found
The Enlightenment of Student Affairs Management in British Universities on Student Work of Chinese University
Students affairs is one essential component in the whole talents cultivation in universities, it indeed has the enhancement for universities to shape the morality and cultivation as its fundamental task, and the cultivation for the new generations who carrying on the national revitalization. The students affairs in universities of UK has been developed for such a long period, now it has the framework with clear notions, completed system and highly specialized which plays an important role in its cultivation system. In the process of promoting educational power to enhance the national competitiveness, Chinese universities should emancipate the mind, updates their thought, and based on the new scenario of the society to embrace the positive experience from educational developed countries selectively, to help the high-equality development of students affairs in universities from our country, to cultivate socialist constructors and successors of all-round development of morality, intelligence, physique, art
First-Class Informatization Is an Important Part of First-Class Universities
First-class universities must have first-class management, and first-class management must rely on first-class information technology. This article systematically sorts out the development process of my country’s college informatization. On the basis of in-depth analysis of the opportunities and challenges that educational modernization brings to the informatization of colleges and universities, the ideas and measures for the advancement of informatization in colleges and universities in the future are proposed
All in One: RGB, RGB-D, and RGB-T Salient Object Detection
Salient object detection (SOD) aims to identify the most attractive objects
within an image. Depending on the type of data being detected, SOD can be
categorized into various forms, including RGB, RGB-D (Depth), RGB-T (Thermal)
and light field SOD. Previous researches have focused on saliency detection
with individual data type. If the RGB-D SOD model is forced to detect RGB-T
data it will perform poorly. We propose an innovative model framework that
provides a unified solution for the salient object detection task of three
types of data (RGB, RGB-D, and RGB-T). The three types of data can be handled
in one model (all in one) with the same weight parameters. In this framework,
the three types of data are concatenated in an ordered manner within a single
input batch, and features are extracted using a transformer network. Based on
this framework, we propose an efficient lightweight SOD model, namely AiOSOD,
which can detect any RGB, RGB-D, and RGB-T data with high speed (780FPS for RGB
data, 485FPS for RGB-D or RGB-T data). Notably, with only 6.25M parameters,
AiOSOD achieves excellent performance on RGB, RGB-D, and RGB-T datasets
Construction, expression, and characterization of rSEA-EGF and in vitro evaluation of its antitumor activity against nasopharyngeal cancer
Antidiabetic effect of Tibetan medicine Tang-Kang-Fu-San on high-fat diet and streptozotocin-induced type 2 diabetic rats
The aim of this study was to investigate the antidiabetic effects of a Tibetan medicine, Tang-Kang-Fu-San (TKFS), on experimental type 2 diabetes mellitus (T2DM) rats and to explore its underlying mechanisms. Firstly two major chemical compositions of TKFS, gallic acid and curcumin, were characterized by HPLC fingerprint analysis. Next T2DM in rats was induced by high-fat diet and a low-dose streptozotocin (STZ 35 mg/kg). Then oral gavage administration of three different doses of TKFS (0.3 g/kg, 0.6 g/kg, and 1.2 g/kg) was given to T2DM rats. Experimental results showed that TKFS dramatically reduced the levels of fasting blood glucose, fasting blood insulin, triglyceride, total cholesterol, LDL cholesterol, and HDL cholesterol, even though it did not alter the animal body weight. The downregulation of phosphorylation-AKT (p-AKT) and glucose transporter-4 (GLUT4) in skeletal muscle of T2DM rats was restored and abnormal pathological changes in pancreas tissues were also improved. Our work showed that TKFS could alleviate diabetic syndromes, maintain the glucose homeostasis, and protect against insulin resistance in T2DM rats, and the improvement of AKT phosphorylation and GLUT4 translocation in skeletal muscle would be one of its possible underlying mechanisms
The Monte Carlo Simulation of the Electronic Local Properties in the Two-Dimensional Disordered System
AbstractUsing Monte Carlo simulation method, we studied the influence of the disorder, eigenenergy and bandwidth on the localization length in disordered system. The results reveal that electronic states of system exhibited localization phenomena with the increase of degree of disorder and the localization length can be reduced by the increasing of disorder degree. Moreover the incremental range of localization length had a trend to descend with increase of bandwidth
SPHR-SAR-Net: Superpixel High-resolution SAR Imaging Network Based on Nonlocal Total Variation
High-resolution is a key trend in the development of synthetic aperture radar
(SAR), which enables the capture of fine details and accurate representation of
backscattering properties. However, traditional high-resolution SAR imaging
algorithms face several challenges. Firstly, these algorithms tend to focus on
local information, neglecting non-local information between different pixel
patches. Secondly, speckle is more pronounced and difficult to filter out in
high-resolution SAR images. Thirdly, the process of high-resolution SAR imaging
generally involves high time and computational complexity, making real-time
imaging difficult to achieve. To address these issues, we propose a Superpixel
High-Resolution SAR Imaging Network (SPHR-SAR-Net) for rapid despeckling in
high-resolution SAR mode. Based on the concept of superpixel techniques, we
initially combine non-convex and non-local total variation as compound
regularization. This approach more effectively despeckles and manages the
relationship between pixels while reducing bias effects caused by convex
constraints. Subsequently, we solve the compound regularization model using the
Alternating Direction Method of Multipliers (ADMM) algorithm and unfold it into
a Deep Unfolded Network (DUN). The network's parameters are adaptively learned
in a data-driven manner, and the learned network significantly increases
imaging speed. Additionally, the Deep Unfolded Network is compatible with
high-resolution imaging modes such as spotlight, staring spotlight, and sliding
spotlight. In this paper, we demonstrate the superiority of SPHR-SAR-Net
through experiments in both simulated and real SAR scenarios. The results
indicate that SPHR-SAR-Net can rapidly perform high-resolution SAR imaging from
raw echo data, producing accurate imaging results
Suppressing Syndecan-1 Shedding Ameliorates Intestinal Epithelial Inflammation through Inhibiting NF- κ
MicroRNA-143 Targets MACC1 to Inhibit Cell Invasion and Migration in Colorectal cancer
<p>Abstract</p> <p>Background</p> <p>MicroRNAs (miRNAs) have been suggested to play a vital role in tumor initiation and progression by negatively regulating oncogenes and tumor suppressors. Quite recently, studies have identified some miRNAs operating to promote or suppress tumor invasion or metastasis via regulating metastasis-related genes, providing potential therapeutic targets on anti-metastasis strategy. Metastasis-associated in colon cancer-1 (MACC1) has been newly identified to express highly in colorectal cancer (CRC) and promote tumor metastasis through transactivating metastasis-inducing HGF/MET signaling pathway. In this study, we investigated whether miRNA 143 is involved in the regulation of MACC1 and thus plays a functional role in CRC.</p> <p>Results</p> <p>Using both in silico prediction and western blot assay, we found the previously reported tumor suppressive miR-143 targeted MACC1 in CRC. The direct interaction between them was confirmed by 3' UTR luciferase reporter gene. In concordance with the inhibitory effects induced by siRNA mediated knockdown of MACC1, restoration of miR-143 by mimics in SW620 cells significantly attenuated cell growth, migration and invasion. It is notable that combined treatment of miR-143 mimics and MACC1 siRNA induced synergistic inhibitory effects compared to either miR-143 mimics or MACC1 siRNA treatment alone. Conversely, reduction of miR-143 by inhibitors in SW480 cells apparently stimulated these phenotypes. Furthermore, we observed that miR-143 level was inversely correlated with MACC1 mRNA expression in CRC tissues.</p> <p>Conclusions</p> <p>Our findings newly described miR-143/MACC1 link and provided a potential mechanism for MACC1 dysregulation and contribution to CRC cell invasion. It may help to estimate the therapeutic utility of miR-143 in CRC.</p
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