127 research outputs found
EnergyâEfficient OilâWater Separation of Biomimetic Copper Membrane with Multiscale Hierarchical Dendritic Structures
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138424/1/smll201701121-sup-0001-S1.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138424/2/smll201701121_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138424/3/smll201701121.pd
Impulsiveness indirectly affects suicidal ideation through depression and simultaneously moderates the indirect effect: A moderated mediation path model
ObjectiveThis study aims to investigate the indirect effect of impulsiveness on suicidal ideation through depression and the moderating effect of impulsiveness on the indirect effect in an integrated path model.MethodsSelf-rating depression scale (SDS), Barratt impulsiveness scale-11th version (BIS-11), and self-rating idea of suicide scale (SIOSS) were applied. A moderated mediation path model was established including impulsiveness, depression, and suicidal ideation as observed variables.ResultsThe main results revealed that the moderated mediation path model fit well in describing the relationships among impulsiveness, depression, and suicidal ideation. The indirect effect of impulsiveness mediated by depression and the moderating effect of impulsiveness on suicidal ideation was significant. Multiple comparisons showed that the indirect effects under different conditions of impulsiveness had statistical differences. The higher the impulsiveness was, the stronger the predictive effect of depression on suicidal ideation was.ConclusionsThe present study confirms that people who have impulsive traits are riskier to generate suicidal thoughts because they are more likely to suffer from depression and that people who are depressive have even higher risk to develop suicidal thoughts when they simultaneously have impulsive traits. In clinical and health care work, when considering depression to prevent suicidal ideation, impulsiveness needs to be monitored throughout the process of premorbid and onset stages of depression
Superfast Liquid Transfer Strategy Through Sliding on a Liquid Membrane Inspired from Scorpion Setae
Although diversified biological structures have evolved fog collection abilities, the typical speeds of the condensed water droplets on these surfaces are too slow to have practical utility. The main challenge focuses on the elimination of the interfacial hydrodynamic resistance without external energy support. Here, an unusual strategy for superfast selfâsupport transfer condensed droplets is supported by sliding on seta of desert scorpion. It can be rapidly wetted by the fog droplets owing to its conical shape with linear gradient channels. A loss of interfacial resistance by this hydrodynamically lubricating water membrane could significantly accelerate the movement of the droplets, thus making its velocity increasing by one order of magnitude, or even more. Inspired by this novel strategy, the novel bioinspired materials are fabricated with the similar gradient channel structures and droplet transportation mode, which can make the condensed droplets spontaneously slide on the lowâfriction liquid membrane. The fundamental understanding of superfast fog capture and the sliding dynamics of condensed droplets in this system could inspire to develop novel materials or various systems to transfer liquid fast and efficiently without external energy support.An unusual strategy for superfast transferring condensed droplets by sliding on liquid membrane of desert scorpion seta is reported. A loss of interfacial resistance could significantly accelerate the droplets by this hydrodynamically lubricating liquid membrane. Then, the bioinspired materials with similar droplet transportation mode are fabricated, which will inspire to develop novel materials to transport liquid without external energy.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146306/1/admi201800802-sup-0001-S1.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146306/2/admi201800802.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146306/3/admi201800802_am.pd
Synergistic Induction of Erlotinib-Mediated Apoptosis by Resveratrol in Human Non-Small-Cell Lung Cancer Cells by Down-Regulating Survivin and Up-Regulating PUMA
Wright-Fisher diffusion bridges
The trajectory of the frequency of an allele which begins at at time and is known to have frequency at time can be modelled by the bridge process of the Wright-Fisher diffusion. Bridges when are particularly interesting because they model the trajectory of the frequency of an allele which appears at a time, then is lost by random drift or mutation after a time . The coalescent genealogy back in time of a population in a neutral Wright-Fisher diffusion process is well understood. In this paper we obtain a new interpretation of the coalescent genealogy of the population in a bridge from a time . In a bridge with allele frequencies of 0 at times 0 and the coalescence structure is that the population coalesces in two directions from to and to such that there is just one lineage of the allele under consideration at times and .
The genealogy in Wright-Fisher diffusion bridges with selection is more complex than in the neutral model, but still with the property of the population branching and coalescing in two directions from time . The density of the frequency of an allele at time is expressed in a way that shows coalescence in the two directions.
A new algorithm for exact simulation of a neutral Wright-Fisher bridge is derived. This follows from knowing the density of the frequency in a bridge and exact simulation from the Wright-Fisher diffusion. The genealogy of the neutral Wright-Fisher bridge is also modelled by branching P\'olya urns, extending a representation in a Wright-Fisher diffusion. This is a new very interesting representation that relates Wright-Fisher bridges to classical urn models in a Bayesian setting.
This paper is dedicated to the memory of Paul Joyce
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