54,126 research outputs found

    Flow behaviour of dielectric liquids in an electric field

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    A family of 10 silicone oils with electrical conductivity similar to 10(-13) S m(-1) (a regime hitherto systematically unexplored) and viscosities ranging from 1 to 2000mPas have been Subjected to an electrical field of up to 1.5kV mm(-1) during flow from a needle. The flow behaviour of these liquids is investigated experimentally in the flow rate regime 10(-8)-10(-12) m(3) s(-1) and we analyse the results using the Ohnesorge number. Due to the low electrical conductivity and high electrical relaxation time of the silicone oils, only unsteady transient jets were found. The onset of this type of jetting has been defined using current measurements and, in contrast to conducting liquids, the non-dimensional jet diameter increases with increase in Ohnesorge number. The time elapsed between the start and finish of jetting increases with increasing Ohnesorge number

    IFN-gamma is associated with risk of Schistosoma japonicum infection in China.

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    Before the start of the schistosomiasis transmission season, 129 villagers resident on a Schistosoma japonicum-endemic island in Poyang Lake, Jiangxi Province, 64 of whom were stool-positive for S. japonicum eggs by the Kato method and 65 negative, were treated with praziquantel. Forty-five days later the 93 subjects who presented for follow-up were all stool-negative. Blood samples were collected from all 93 individuals. S. japonicum soluble worm antigen (SWAP) and soluble egg antigen (SEA) stimulated IL-4, IL-5 and IFN-gamma production in whole-blood cultures were measured by ELISA. All the subjects were interviewed nine times during the subsequent transmission season to estimate the intensity of their contact with potentially infective snail habitats, and the subjects were all re-screened for S. japonicum by the Kato method at the end of the transmission season. Fourteen subjects were found to be infected at that time. There was some indication that the risk of infection might be associated with gender (with females being at higher risk) and with the intensity of water contact, and there was evidence that levels of SEA-induced IFN-gamma production were associated with reduced risk of infection

    Reduction of Proximity Effects on UHF Passive RFID Systems by Using Tags with Polarization Diversity

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    A new technique that enables passive ultra high fre- quency (UHF) radio frequency identification (RFID) tags to be read when they are placed in close proximity in an array is pre- sented. This paper demonstrates that, in a linear tag array with a tag separation of 1 cm, the interaction between the backscat- tered waves and incident wave causes a significant degradation in tag sensitivity. It is found that the use of tags that have polariza- tion diversity can improve the read performance when they are placed in close proximity to one another compared with conven- tional linear tags. Two ways of achieving polarization diversity are studied in this paper, namely: 1) using a circularly polarized tag and 2) using a cross-polarized tag pair. Both methods show an improvement in close proximity read performance and it is exper- imentally demonstrated that by using cross-polarized tag pairs in an array, one achieves on average a 2.6-dB increase in read power margin for a 57-tag array with 1 cm separation compared with using conventional linearly polarized tags.This work has been supported by UK Engineering and Physical Science Research Council via the COPOSII project.This is the final published version. It first appeared at http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=7042269

    Failure analysis of a steel motorcycle kickstand

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    Copyright @ 2009 Springer US.A fractured steel motorcycle kickstand was metallurgically investigated using a range of failure analysis tools [visual examination, energy dispersive X-ray (EDX) analysis, electron microprobe analysis (EPMA), scanning electron microscopy (SEM), fractography, optical microscopy, hardness testing and non-destructive testing (NDT)]. The steel kickstand’s composition, its microstructure, electron fractographs, and mechanical test results have been critically interpreted. Some evidence of wear damage, in the failed kickstand, was observed. The microstructural and fractographic analyses showed pre-existing micro-cracks which were believed to have grown to result in ductile failure followed by acceleration of corrosion. Recommendations have been made to avoid the failure of the motorcycle kickstand

    Lake-sediment records of recent climate variability in northwest China’s drylands.

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    ChIP-Array: Combinatory analysis of ChIP-seq/chip and microarray gene expression data to discover direct/indirect targets of a transcription factor

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    Chromatin immunoprecipitation (ChIP) coupled with high-throughput techniques (ChIP-X), such as next generation sequencing (ChIP-Seq) and microarray (ChIP-chip), has been successfully used to map active transcription factor binding sites (TFBS) of a transcription factor (TF). The targeted genes can be activated or suppressed by the TF, or are unresponsive to the TF. Microarray technology has been used to measure the actual expression changes of thousands of genes under the perturbation of a TF, but is unable to determine if the affected genes are direct or indirect targets of the TF. Furthermore, both ChIP-X and microarray methods produce a large number of false positives. Combining microarray expression profiling and ChIP-X data allows more effective TFBS analysis for studying the function of a TF. However, current web servers only provide tools to analyze either ChIP-X or expression data, but not both. Here, we present ChIP-Array, a web server that integrates ChIP-X and expression data from human, mouse, yeast, fruit fly and Arabidopsis. This server will assist biologists to detect direct and indirect target genes regulated by a TF of interest and to aid in the functional characterization of the TF. ChIP-Array is available at http://jjwanglab.hku.hk/ChIP-Array, with free access to academic users. © 2011 The Author(s).published_or_final_versio

    Impacts of yeast metabolic network structure on enzyme evolution

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    Vitkup et al. recently presented an analysis of the influence of yeast metabolic network structure on enzyme evolution; different conclusions are reached when modularity is properly accounted for
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