40 research outputs found

    Imaging Electronic Correlations in Twisted Bilayer Graphene near the Magic Angle

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    Twisted bilayer graphene with a twist angle of around 1.1{\deg} features a pair of isolated flat electronic bands and forms a strongly correlated electronic platform. Here, we use scanning tunneling microscopy to probe local properties of highly tunable twisted bilayer graphene devices and show that the flat bands strongly deform when aligned with the Fermi level. At half filling of the bands, we observe the development of gaps originating from correlated insulating states. Near charge neutrality, we find a previously unidentified correlated regime featuring a substantially enhanced flat band splitting that we describe within a microscopic model predicting a strong tendency towards nematic ordering. Our results provide insights into symmetry breaking correlation effects and highlight the importance of electronic interactions for all filling factors in twisted bilayer graphene.Comment: Main text 9 pages, 4 figures; Supplementary Information 25 page

    Electronic correlations in twisted bilayer graphene near the magic angle

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    Twisted bilayer graphene with a twist angle of around 1.1° features a pair of isolated flat electronic bands and forms a platform for investigating strongly correlated electrons. Here, we use scanning tunnelling microscopy to probe the local properties of highly tunable twisted bilayer graphene devices and show that the flat bands deform when aligned with the Fermi level. When the bands are half-filled, we observe the development of gaps originating from correlated insulating states. Near charge neutrality, we find a previously unidentified correlated regime featuring an enhanced splitting of the flat bands. We describe this within a microscopic model that predicts a strong tendency towards nematic ordering. Our results provide insights into symmetry-breaking correlation effects and highlight the importance of electronic interactions for all filling fractions in twisted bilayer graphene

    Compensatory remodeling of a septo-hippocampal GABAergic network in the triple transgenic Alzheimer’s mouse model

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    Abstract Background Alzheimer’s disease (AD) is characterized by a progressive loss of memory that cannot be efficiently managed by currently available AD therapeutics. So far, most treatments for AD that have the potential to improve memory target neural circuits to protect their integrity. However, the vulnerable neural circuits and their dynamic remodeling during AD progression remain largely undefined. Methods Circuit-based approaches, including anterograde and retrograde tracing, slice electrophysiology, and fiber photometry, were used to investigate the dynamic structural and functional remodeling of a GABAergic circuit projected from the medial septum (MS) to the dentate gyrus (DG) in 3xTg-AD mice during AD progression. Results We identified a long-distance GABAergic circuit that couples highly connected MS and DG GABAergic neurons during spatial memory encoding. Furthermore, we found hyperactivity of DG interneurons during early AD, which persisted into late AD stages. Interestingly, MS GABAergic projections developed a series of adaptive strategies to combat DG interneuron hyperactivity. During early-stage AD, MS-DG GABAergic projections exhibit increased inhibitory synaptic strength onto DG interneurons to inhibit their activities. During late-stage AD, MS-DG GABAergic projections form higher anatomical connectivity with DG interneurons and exhibit aberrant outgrowth to increase the inhibition onto DG interneurons. Conclusion We report the structural and functional remodeling of the MS-DG GABAergic circuit during disease progression in 3xTg-AD mice. Dynamic MS-DG GABAergic circuit remodeling represents a compensatory mechanism to combat DG interneuron hyperactivity induced by reduced GABA transmission

    Research of grounded DC electrical tree growth properties in XLPE

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    Grounded DC tree is a serious threat for the safe operation of XLPE cable. In this paper, growth properties of grounded DC electrical trees in XLPE under ±40kV DC voltage were investigated and analyzed. The results showed that DC voltage polarity had a remarkable impact on the growth characteristics of grounded electrical tree. Sparse-branch and dense-branch electrical trees were more likely to form under positive and negative voltage, respectively. Meanwhile, the time of typical grounded DC tree samples growing to 1mm was also calculated. The results indicated that the average growing time under positive voltage could be a bit shorter than that under negative voltage. The results in this paper can help in the understanding of DC tree mechanism and provide a support for the later experiments

    Research on External Insulation Characteristics of Composite Cross-Arm of 10 kV Distribution Network Based on Multi-Factor Aging

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    With the application of the composite cross-arm in power systems, comprehensive anti-aging performance is a key factor to determine whether it can operate safely. In order to study the influence of the operating environment on the external insulation characteristics of composite cross-arms of distribution networks, various aging conditions such as voltage, rain, temperature, humidity, salt fog and ultraviolet light were simulated in a climate chamber based on the real operation conditions of the 10-kV composite cross-arm. A multi-factor aging test of composite cross-arms with two kinds of cross-section shapes (T-shaped and square) was carried out for 5000 h. The change trends of leakage current and flashover voltage of the composite cross-arms before and after aging were analyzed. Finally, the aging mechanism of the silicone rubber sheaths was analyzed to further explain the reasons for the change of external insulation performance of composite cross-arms. The results show that the leakage current rising rate of T-shaped and square composite cross-arms after aging increases significantly, and the minimum flashover voltage decreases to 58.3 kV and 49.502 kV, respectively. The results of FTIR, SEM and hydrophobic angle tests show that, after aging, the performance of the silicone rubber outer sheath material decreases in varying degrees. In general, UV aging has the greatest influence on the external insulation characteristics of composite cross arms. Generally speaking, after 5000 h of multi factor aging, although the external insulation characteristics of the 10-kV composite cross-arm decreases to a certain extent, there is still enough margin to meet the normal operation

    Effect of Nano-SiO<sub>2</sub> Modification on Mechanical and Insulation Properties of Basalt Fiber Reinforced Composites

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    Basalt fiber (BF) has high mechanical strength, good insulation performance and low cost. It is suitable to be used as reinforcement material in the manufacture of electrical equipment. However, the large surface inertia of basalt fiber makes it difficult to combine with the matrix material, which seriously limits its service life and application scenarios. In addition, the serious vacancy in the research of insulation properties also limits its production and application in the electrical field. Therefore, in order to solve the problem of difficult bonding between basalt fiber and resin matrix and make up for the research blank of basalt fiber composites in insulation performance, this paper provides a basalt fiber modification method—SiO2 coating, and tests the insulation and mechanical properties of the modified composite. We used nano-SiO2 coating solution to modify basalt fiber, and manufactured BF/resin composite (BFRP) by hand lay-up and hot-pressing technology, and experimentally analyzed the influence of nano-SiO2 content on the mechanical and insulation properties of the modified composite. Fourier transform infrared spectrum and scanning electron microscope analysis showed that nano-SiO2 was successfully coated on basalt fibers. Through the microdroplet debonding test, it was found that the IFSS of fiber/resin was improved by 35.15%, 72.97 and 18.9%, respectively, after the modification of the coating solution with SiO2 concentration of 0.5%, 1% and 1.5%, showing better interface properties; the single fiber tensile test found that the tensile strength of the modified fiber increased slightly. Among all composites, 1 wt% SiO2 coating modified composites showed the best comprehensive properties. The surface flashover voltage and breakdown field strength reached 13.12 kV and 33 kV/mm, respectively, which were 34.6% and 83% higher than unmodified composite. The dielectric loss is reduced to 1.43%, which is 33.8% lower than the dielectric loss (2.16%) of the untreated composite, showing better insulation ability; the tensile strength, bending strength and interlaminar shear strength were increased to 618.22 MPa, 834.74 MPa and 16.29 MPa, respectively, which were increased by 53%, 42.4% and 59.7%, compared with untreated composites. DMA and glass transition temperature showed that the modified composite had better heat resistance. TGA experiments showed that the resin content of the modified composite increased, and the internal structure of the composite became denser

    Blending Modification of Alicyclic Resin and Bisphenol A Epoxy Resin to Enhance Salt Aging Resistance for Composite Core Rods

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    In order to promote the application of composite insulators in coastal areas with high temperature, high humidity and high salt, it is of great importance to develop matrix resin with salt corrosion resistance for composite core rods. In this study, bisphenol A epoxy resin was modified by blending with alicyclic epoxy resin (2021P). Three different proportions of 2021P/DGEBA blend resins (0% 2021P/DGEBA, 10% 2021P/DGEBA and 20% 2021P/DGEBA) were prepared, and the high salt medium corrosion test was carried out. The physicochemical (FTIR, DMA, TGA) and electrical properties (dielectric loss, leakage current and breakdown field strength) of the blend resin before and after aging were tested and analyzed, and the optimal blend proportion was determined. The results showed that after salt aging, the Tg of 0% 2021P/DGEBA decreased to 122.99 &deg;C, while the Tg of 10% 2021P/DGEBA reached 134.89 &deg;C; The leakage current of 0% 2021P/DGEBA increased to 48.994 &mu;A, while that of 10% 2021P/DGEBA only increased to 44.549 &mu;A; The breakdown field strength of 0% 2021P/DGEBA dropped to 40.36 kv/mm, while that of 10% 2021P/DGEBA only dropped to 43.63 kv/mm. The introduction of 2021P enhanced the salt corrosion resistance of the blend resin, which could hinder the penetration, diffusion and erosion of external media (such as Na+, Cl&minus;, H2O, etc.) to the matrix resin. The comprehensive properties of 10% 2021P/DGEBA blend system reached the best, which was better than other blending resins, showing great application potential

    Cu<sup>2+</sup>–Citrate–Chitosan Complex Nanoparticles for the Chemodynamic Therapy of Lung Cancer

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    Lung cancer poses a significant threat to human health. Surgical intervention is the preferred treatment modality for lung cancer, but a large number of patients are deprived of the opportunity for surgery for various reasons and are compelled to undergo radiotherapy and chemotherapy, which entail systemic adverse reactions. In recent years, with the advancement of nanomedicine, chemodynamic therapy (CDT) based on free radicals has been extensively investigated. In this study, we fabricated copper–citrate–chitosan composite nanoparticles (CuCC NPs) by encapsulating copper–citrate complexes with natural chitosan polymers, resulting in a substantial reduction in the biotoxicity of copper ions. The CuCC NPs selectively accumulated in tumor tissues through the enhanced permeability and retention effect (EPR) and gradually degraded within the acidic and glutathione (GSH)-rich microenvironment of the tumor, thereby releasing the loaded copper ions. Through CDT, the copper ions converted the overexpressed hydrogen peroxide (H2O2) in the tumor tissue into hydroxyl radicals (•OH), leading to the eradication of tumor cells. In animal experiments, CuCC NPs exhibited remarkable efficacy in CDT. Further histopathological and hematological analyses demonstrated that CuCC NPs could induce substantial apoptosis in tumor tissues while maintaining an extremely high level of safety
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