The Joint Link of the rs1051730 and rs1902341 Polymorphisms and Cigarette Smoking to Peripheral Artery Disease and Atherosclerotic Lesions of Different Arterial Beds

Genome-wide association studies have discovered numerous single nucleotide polymorphisms contributing to peripheral artery disease (PAD), but their joint effects with risk factors like cigarette smoking on disease susceptibility have not been systematically investigated. The present study looked into whether CS mediates the effects of GWAS loci on the development of PAD and atherosclerotic lesions in different arterial bed

Антикоагулянтная терапия тромбоэмболии легочной артерии с тромбозом правых камер сердца

Acute pulmonary embolism (PE) is a relatively common vascular disease with potentially life-threatening complications. Right heart thrombi deteriorate the prognosis. Due to the known high lethality, such a clinical situation requires immediate diagnosis and treatment. With the existing different management options for intracardiac blood clots, the optimal one is still uncertain. The article describes the experience of therapeutic and diagnostic tactics in a patient with PE and thrombosis of two right chambers of the heart with a favorable outcome while the conservative approach was used.Тромбоэмболия легочной артерии (ТЭЛА) является относительно распространенным сосудистым заболеванием с потенциально опасными для жизни осложнениями. Тромбоз правых отделов сердца, несомненно, усугубляет прогноз. В связи с высокой летальностью подобная клиническая ситуация представляет собой проблему, требующую немедленной диагностики и лечения. При существующих различных вариантах ведения внутрисердечных тромбов оптимальный из них все еще остается неопределенным. Представлен опыт консервативной лечебно-диагностической тактики у пациента с ТЭЛА и тромбозом двух правых камер сердца с благоприятным исходом при консервативном подходе

Study of the process e+e−→ωπ0→π+π−π0π0e^+e^- \to \omega\pi^0 \to \pi^+\pi^-\pi^0\pi^0 in the energy range 1.05−2.001.05-2.00 GeV with SND

The process $e^+e^- \to \omega\pi^0 \to \pi^+\pi^-\pi^0\pi^0$ is studied in the center-of-mass energy region $1.05-2.00$ GeV using data with an integral luminosity of about 35 pb$^{-1}$ collected with the SND detector at the VEPP-2000 $e^+e^-$ collider. In the energy range under study, the value of the measured Born cross section varies from 0.7 to 18 nb. The statistical uncertainty of the cross section is $2-23$%, while the systematic uncertainty is in the range of $3.0-14.2$%. The results are consistent with previous measurements but have better accuracy.Comment: 13 pages, 11 figure

Study of the process e+e−→ηπ0γe^+e^- \to \eta\pi^0\gamma in the energy range \sqrt{s} = \mbox{1.05-2.00} GeV with the SND detector

The process $e^+e^-\to\eta\pi^0\gamma$ is studied in the center-of-mass energy range 1.05-2.00 GeV using data with an integrated luminosity of 94.5 pb$^{-1}$ collected by the SND detector at the VEPP-2000 $e^+e^-$ collider. The $e^+e^-\to\eta\pi^0\gamma$ cross section is measured for the first time. It is shown that the dominant mechanism of this reaction is the transition through the $\omega\eta$ intermediate state. The measured cross section of the subprocess $e^+e^-\to\omega\eta\to\eta\pi^0\gamma$ is consistent with previous measurements in the $e^+e^-\to\pi^+\pi^-\pi^0\eta$ mode. It is found, with a significance of 5.6$\sigma$, that the process $e^+e^-\to\eta\pi^0\gamma$ is not completely described by hadronic vector-pseudoscalar intermediate states. The cross section of this missing contribution, which can originate from radiation processes, e. g. $e^+e^-\to a_{0}(1450)\gamma$, is measured. It is found to be 15-20 pb in the wide energy range from 1.3 to 1.9 GeV.Comment: 10 pages, 6 figures, to be submitted to European Physical Journal

Measurement of the neutron timelike electromagnetic form factor with the SND detector

The results of the measurement of the $e^+e^- \to n \bar{n}$ cross section and effective neutron timelike form factor are presented. The data taking was carried out in 2020-2021 at the VEPP-2000 $e^+e^-$ collider in the center-of-mass energy range from 1891 to 2007 MeV. The general purpose nonmagnetic detector SND is used to detect neutron-antineutron events. The event selection is performed using the time-of-flight technique. The measured cross section is 0.4-0.6 nb. The neutron form factor in the energy range under study varies from 0.3 to 0.2.Comment: 13 pages, 8 figure

Study of dynamics of the process e+e−→π+π−π0e^+e^-\to \pi^+\pi^-\pi^0 in the energy range 1.15--2.00 GeV

The dynamics of the process $e^+e^- \to \pi^+\pi^-\pi^0$ is studied in the energy region from 1.15 to 2.00 GeV using data accumulated with the SND detector at the VEPP-2000 $e^+e^-$ collider. The Dalitz plot distribution and $\pi^+\pi^-$ mass spectrum are analyzed in a model including the intermediate states $\rho(770)\pi$, $\rho(1450)\pi$, and $\omega\pi^0$. As a result, the energy dependences of the $\rho(770)\pi$ and $\rho(1450)\pi$ cross sections and the relative phases between the $\rho(770)\pi$ amplitude and the $\rho(1450)\pi$ and $\omega\pi^0$ amplitudes are obtained. The $\rho(1450)\pi$ cross section has a peak in the energy region of the $\omega(1650)$ resonance (1.55-1.75 GeV). In this energy range the contributions of the $\rho(770)\pi$ and $\rho(1450)\pi$ states are of the same order of magnitude. No resonance structure near 1.65 GeV is observed in the $\rho(770)\pi$ cross section. We conclude that the intermediate state $\rho(1450)\pi$ gives a significant contribution to the decay of $\omega (1650)\to\pi^+\pi^-\pi^0$, whereas the $\rho(770)\pi$ mechanism dominates in the decay $\omega(1420)\to\pi^+\pi^-\pi^0$.Comment: 9 pages, 7 figures, 3 table