Герпес-вирусы 6 и 7 типа: взгляд педиатра

Herpetic diseases are widespread among cancer patients and are of interest to specialists in various fields. It is herpetic infections that are often common among cases of infant mortality. The main causative agents of herpetic phenomena in humans are manifested by the 8 most studied types of the virus. The article presents a review of modern scientific literature on herpetic diseases caused by herpes viruses 6 and 7. The issues of the history of the study of diseases, etiology, features of the distribution, the pathogenesis of diseases, a wide manifestation of manifestations in childhood, diagnosis, and tactics of managing patients are outlined.Герпетические инфекции широко распространены в человеческой популяции, и интерес к ним среди специалистов разного профиля постоянно возрастает, так как они являются причиной развития большого спектра соматических и онкологических заболеваний. Именно герпетические инфекции часто являются причинами преждевременных родов, младенческой смертности. Основные возбудители герпетических инфекций у человека представлены 8 наиболее изученными типами вируса. В статье представлен обзор современной научной литературы по вопросам герпетических инфекций, вызванных герпес-вирусами 6-го и 7-го типа. Изложены вопросы истории изучения заболевания, этиология, особенности распространения, патогенез заболевания, основные клинические проявления в детском возрасте, диагностика и тактика ведения пациентов

колективна монографія

Кримінальний процесуальний кодекс 2012 року: ідеологія та практика правозастосування: колективна монографія / за заг. ред. Ю. П. Аленіна ; відпов. за вип. І. В. Гловюк. - Одеса : Видавничий дім «Гельветика», 2018. - 1148 с

EFFECT OF NEURODEGENERATIVE CHANGES IN THE BRAIN ON THE FORMATION OF THE DISEASE CLINICAL PICTURE IN PATIENTS WITH MULTIPLE SCLEROSIS

The aim of the study was to determine the relationship of global and regional cerebral atrophy and volume of demyelination lesions in the brain with a clinical picture in patients with multiple sclerosis (MS). The study involved 55 patients with MS. Control group included 22 healthy volunteers. Patients were divided into groups according to the severity of disability, the type and duration of disease. Assessment of general and regional atrophy was performed by post-process volumetric segmentation of MRI data, which was acquired at 3T Philips Achieva scanner. The post-processing was done with the FreeSurfer software. It is shown that in MS patients brain atrophy develops both by means of gray matter (including the cortex and subcortical structures), and white matter, along with demyelination. Global and regional atrophy is associated with the severity of disability of patients according to EDSS scale, but not with the duration and type of the disease. Neurodegenerative changes of brain structures evolve with different rates, have different intensity and determine the set of symptoms of neurological impairment and severity of disability, which indicates the presence of certain patterns of the process of atrophy in the brain, forming the clinical picture of the disease