Defining Optimal Brain Health in Adults A Presidential Advisory From the American Heart Association/American Stroke Association

Cognitive function is an important component of aging and predicts quality of life, functional independence, and risk of institutionalization. Advances in our understanding of the role of cardiovascular risks have shown them to be closely associated with cognitive impairment and dementia. Because many cardiovascular risks are modifiable, it may be possible to maintain brain health and to prevent dementia in later life. The purpose of this American Heart Association (AHA)/American Stroke Association presidential advisory is to provide an initial definition of optimal brain health in adults and guidance on how to maintain brain health. We identify metrics to define optimal brain health in adults based on inclusion of factors that could be measured, monitored, and modified. From these practical considerations, we identified 7 metrics to define optimal brain health in adults that originated from AHA's Life's Simple 7: 4 ideal health behaviors (nonsmoking, physical activity at goal levels, healthy diet consistent with current guideline levels, and body mass index < 25 kg/m(2)) and 3 ideal health factors (untreated blood pressure < 120/< 80 mm Hg, untreated total cholesterol < 200 mg/dL, and fasting blood glucose < 100 mg/dL). In addition, in relation to maintenance of cognitive health, we recommend following previously published guidance from the AHA/American Stroke Association, Institute of Medicine, and Alzheimer's Association that incorporates control of cardiovascular risks and suggest social engagement and other related strategies. We define optimal brain health but recognize that the truly ideal circumstance may be uncommon because there is a continuum of brain health as demonstrated by AHA's Life's Simple 7. Therefore, there is opportunity to improve brain health through primordial prevention and other interventions. Furthermore, although cardiovascular risks align well with brain health, we acknowledge that other factors differing from those related to cardiovascular health may drive cognitive health. Defining optimal brain health in adults and its maintenance is consistent with the AHA's Strategic Impact Goal to improve cardiovascular health of all Americans by 20% and to reduce deaths resulting from cardiovascular disease and stroke by 20% by the year 2020. This work in defining optimal brain health in adults serves to provide the AHA/American Stroke Association with a foundation for a new strategic direction going forward in cardiovascular health promotion and disease prevention

Eleven strategies for making reproducible research and open science training the norm at research institutions

Reproducible research and open science practices have the potential to accelerate scientific progress by allowing others to reuse research outputs, and by promoting rigorous research that is more likely to yield trustworthy results. However, these practices are uncommon in many fields, so there is a clear need for training that helps and encourages researchers to integrate reproducible research and open science practices into their daily work. Here, we outline eleven strategies for making training in these practices the norm at research institutions. The strategies, which emerged from a virtual brainstorming event organized in collaboration with the German Reproducibility Network, are concentrated in three areas: (i) adapting research assessment criteria and program requirements; (ii) training; (iii) building communities. We provide a brief overview of each strategy, offer tips for implementation, and provide links to resources. We also highlight the importance of allocating resources and monitoring impact. Our goal is to encourage researchers - in their roles as scientists, supervisors, mentors, instructors, and members of curriculum, hiring or evaluation committees - to think creatively about the many ways they can promote reproducible research and open science practices in their institutions

Análisis de eficiencia de protocolos de enrutamiento en implementación de red inalámbrica mesh en instalaciones de la facultad de ingeniería en electricidad y computación (fiec) realizando llamadas de voz sobre ip.

En la actualidad las redes malladas inalámbricas se han convertido en una nueva área de la tecnología destinada a jugar un papel importante en el escenario de las redes inalámbricas de banda ancha debido a las ventajas que nos ofrece este tipo de redes, lo cual ha permitido un amplio aumento de aplicaciones tanto como una plataforma de investigación y como una tecnología que puede ser explotada comercialmente. Este proyecto se basará en analizar las redes Inalámbricas Malladas usando cuatro protocolos de enrutamiento mallado, empleando las dos clases representativas de los mismos: proactivos y reactivos. Para ello, se verificara la calidad de servicio (QoS) el cual es un factor importante en su implementación que cada uno de ellos nos brinda. Los parámetros que serán analizados en el proyecto serán: el consumo de ancho de banda, jitter, retraso, pérdida de paquetes VOIP

A pressure drop correlation for low Reynolds number Newtonian flows through a rectangular orifice in a similarly shaped micro-channel

Current microfabrication methods mean that rectangular orifices in similarly shaped micro-channels are often found in microfluidic devices. The power required to overcome the pressure drop across such orifices is often of importance. In the contribution reported here, numerical results for low Reynolds number incompressible Newtonian fluid flow through rectangular orifice in similarly shaped micro-channel have been used to develop a correlation for pressure drop arising from the orifice. The correlation, which was motivated by theoretical developments, indicates that the pressure drop is proportional to the average velocity through the orifice, and a function of the orifice contraction ratio, length-to-width ratio and, most particularly, aspect ratio.V. Zivkovic, P. Zerna, Z.T. Alwahabi, M.J. Bigg

Utilización del software cypecad en el diseño sismo resistente de un edificio de cinco pisos utilizando como material el hormigón armado

En el Ecuador existen varios programas de computadora de los que el ingeniero civil dedicado al cálculo estructural sismo resistente se sirve para el diseño de sus estructuras, programas que tienen gran acogida a nivel mundial debido a su alta confiabilidad en la presentación de resultados, tales como momentos flectores, torsores, cortantes y cargas axiales. En este trabajo, mediante el diseño de un edificio de oficinas de cinco niveles, se introduce a los diseñadores estructurales hacia el uso de un software llamado Cypecad que, además de su fácil manejo, genera los planos estructurales de la obra en formato convencional, junto con la respectiva memoria técnica de cálculo. Por otra parte, con fines comparativos, realizamos el mismo diseño con el programa Sap2000 para que al término de la lectura de este trabajo, el lector esté en condiciones de obtener sus propias conclusiones de acuerdo a los resultados presentados en ambos diseños

10Gbps POF ribbon transmission for optical interconnects

In this paper, we present a solution for optical interconnects with Polymer Optical Fibers, based on a parallel approach: a ribbon made or 4 fibers is used in conjunction with a VCSEL array and a photodiode array, for transmitting a total data rate of 10Gbps over a distance of 25m

In-building and home networks using POF

We review the use of polymer optical fibers as the forthcoming optical technology for in-building and home networks proving that it offers, at low cost, the QoS required by the next evolution of services