High Cortico-Trabecular Transitional Zone Porosity and Reduced Trabecular Density in Men and Women with Stress Fractures

To determine whether stress fractures are associated with bone microstructural deterioration we quantified distal radial and the unfractured distal tibia using high resolution peripheral quantitative computed tomography in 26 cases with lower limb stress fractures (15 males, 11 females; mean age 37.1 ± 3.1 years) and 62 age-matched healthy controls (24 males, 38 females; mean age 35.0 ± 1.6 years). Relative to controls, in men, at the distal radius, cases had smaller cortical cross sectional area (CSA) (p = 0.012), higher porosity of the outer transitional zone (OTZ) (p = 0.006), inner transitional zone (ITZ) (p = 0.043) and the compact-appearing cortex (CC) (p = 0.023) while trabecular vBMD was lower (p = 0.002). At the distal tibia, cases also had a smaller cortical CSA (p = 0.008). Cortical porosity was not higher, but trabecular vBMD was lower (p = 0.001). Relative to controls, in women, cases had higher distal radial porosity of the OTZ (p = 0.028), ITZ (p = 0.030) not CC (p = 0.054). Trabecular vBMD was lower (p = 0.041). Distal tibial porosity was higher in the OTZ (p = 0.035), ITZ (p = 0.009), not CC. Stress fractures are associated with compromised cortical and trabecular microstructure

CONVENTIONAL VERSUS LASER-ASSISTED THERAPY WITH AGGRESSIVE PERIODONTITIS

Aim of the study To evaluate tissue response in aggressive periodontitis (AgP) after conventional and conventional supplemented with laser-assisted therapy. Material and methods This study included 50 subjects with AgP, aged 10 -24 year, which were divided into two subgroups. Firs subgroup 25 subjects treated only with conventional therapy (CP) and second subgroup of 25 subjects which were treated with laser assisted therapy (CP-LA). Low-level diode laser (630-670 nm, 1.875 J/cm) was applied, each sextant for 4 minutes, Scorpion C- 405 7A (Optica Laser, Sofia, Bulgaria). The control group consisted of 20 individuals, aged 13-24 years, without signs of periodontal disease. Gingival tissue biopsies were obtained from the controls and from the study group before and after conventional and with laser assisted treatment. Tissue specimens were embedded in paraffin and cryostat procedures were performed. Results Gingival tissue specimens from study group compared to controls showed dense infiltrate. Subject with AgP revealed heterogeneous inflammatory infiltrate with dense and less dense areas. Almost equal values from quantitative measurements of connective tissue inflammatory infiltrate were obtained. Mean values for study group before treatment were 39,18± 14,02 . For the first subgroup mean values ranged 35,92± 14,02, and mean values for the second subgroup were 35.01 ± 13.25. Qualitative analysis in study group after conventional without and with lasser assistance revealed insignificant values of mononuclear and plasma cells and Russell bodies. Conclusions Laser application did not induce quantitaive nor qualitative changes in the gingival tissue inflammatory infiltrate in study group. On the basis of our findings we suggest that low level laser assisted therapy does not proof to be efficient in the treatment of aggressive periodontitis