GFAP-DNSynCAM1 mice have reduced anxiety in the acoustic startle paradigm.

<p>(<b>A</b>) Startle amplitudes for the GFAP-DNSynCAM1 (black bars; n = 8) and WT (white bars; n = 7) mice for each of the sound intensities tested. Data points represent means ± SEM. Data were analyzed with ANOVA for repeated measures. (<b>B</b>) The average startle amplitudes for each genotype during baseline (0 db) and after different stimulation intensities (80–120 db). (<b>C</b>) Percent response of GFAP-DNSynCAM1 (black bars; n = 9) and WT (white bars; n = 8) in the PPI test using two different stimuli intensities (110 and 120 db). The data are represented as the mean ± SEM and analyzed by two- way ANOVA (intensity by genotype) followed by unpaired t test post hoc analysis. * p<0.05.</p