10 research outputs found

    The behavior of ß-lactoglobulin protein in plate heat exchanger’s channel during milk heat treatment

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    A major problem related to heat treatment of milk is formation of deposits. This is due to the chemical alteration of β-lactoglobulin protein that leads to formation of coatings on the walls of the equipment. These deposits induce losses in the thermal performance of the heat exchanger. In order to provide an adequate prediction of these deposits, we present a two-dimensional (2D) modelling study of the channel of a plate heat exchanger. Compared with the former studies, where the domain is related to a single plate, our work is related to the area between the two plates. This approach will allow a better understanding and description of the evolution and behaviour of β-lactoglobulin protein. Equations for fluid flow, energy, and fouling were resolved. Special boundary conditions had been implemented to link the amount of deposits with thermal transfer. Predicted results for the amount of fouling deposit on the wall were validated by comparisons with experimental data available in literature. The behaviour of β-lactoglobulin protein was studied by analyzing its distribution in the channel

    La fracturation et les bandes de déformation dans la région d’El Kohol (Atlas saharien central, Algérie): analyse fractale, lois d’échelles et modèle de réseaux de fractures discrètes

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    The aim of this paper is focused on the study of natural fractures and deformation bands in El Kohol structure, located in the Djebel Amour in the Central Saharan Atlas, Algeria. The field observations and measurements were performed through two localities on the forelimb and two others on the backlimb of the structure. The outcrop study has shown the existence of five fracture sets and three deformation bands sets. The spacing and length distribution models of the different fractures sets obey to a power law. The mechanical layer thickness analysis for the whole formations shows the existence of twelve mechanical units with a stratabound control. The deformation bands show an increasing in their numbers, and a decreasing in their spacing when they approach the major faults. The fractal analysis of faults and fractures, as well as the deformation bands show a fractal character of 2D dimension. A good correlation coefficients is obtained from the comparison between the density and the intensity parameters (Pxy) calculated from the discrete fracture network (DFN) modelling, and those from the outcrops. The model developed is discussed related to deformation events recognized in the area.[fr] Ce travail porte sur l’étude de la fracturation naturelle et les bandes de déformation dans la structure plicative d’El Kohol, du le Djebel Amour, dans l’Atlas saharien central. Les observations et les mesures ont été effectuées à travers deux stations sur le flanc court ou avant de la structure, et deux stations sur le flanc long ou arrière. L’étude a montré l’existence de cinq familles de fractures et de trois familles de bandes de déformation. Les modèles de distribution des espacements et des longueurs des différentes familles de fractures obéit à une loi de type puissance. L’analyse mécanostratigraphique montre une subdivision des formations étudiées en douze unités mécaniques. Les bandes de déformation montrent une augmentation de leurs nombres, ainsi qu’une réduction de leurs espacements à l’approche des accidents majeurs. Les analyses fractales effectuées sur les failles, les fractures et sur les bandes de déformation montrent un caractère fractal de dimension 2. La comparaison des paramètres de densité et d’intensité (Pxy) obtenus à partir de la modélisation du réseau de fractures discrètes (DFN) avec ceux calculés sur le terrain montrent de bons coefficients de corrélation. Le modèle établi est discuté à la lumière des phases de déformation reconnues dans la région

    In Vitro and In Vivo Antimicrobial Activity of the Novel Peptide OMN6 against Multidrug-Resistant <i>Acinetobacter baumannii</i>

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    The rapid worldwide spread of antimicrobial resistance highlights the significant need for the development of innovative treatments to fight multidrug-resistant bacteria. This study describes the potent antimicrobial activity of the novel peptide OMN6 against a wide array of drug-resistant Acinetobacter baumannii clinical isolates. OMN6 prevented the growth of all tested isolates, regardless of any pre-existing resistance mechanisms. Moreover, in vitro serial-passaging studies demonstrated that no resistance developed against OMN6. Importantly, OMN6 was highly efficacious in treating animal models of lung and blood infections caused by multidrug-resistant A. baumannii. Taken together, these results point to OMN6 as a novel antimicrobial agent with the potential to treat life-threatening infections caused by multidrug-resistant A. baumannii avoiding resistance
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