936 research outputs found
Material Dependence of the Wire-Particle Casimir Interaction
We study the Casimir interaction between a metallic cylindrical wire and a
metallic spherical particle by employing the scattering formalism. At large
separations, we derive the asymptotic form of the interaction. In addition, we
find the interaction between a metallic wire and an isotropic atom, both in the
non-retarded and retarded limits. We identify the conditions under which the
asymptotic Casimir interaction does not depend on the material properties of
the metallic wire and the particle. Moreover, we compute the exact Casimir
interaction between the particle and the wire numerically. We show that there
is a complete agreement between the numerics and the asymptotic energies at
large separations. For short separations, our numerical results show good
agreement with the proximity force approximation
Universality versus material dependence of fluctuation forces between metallic wires
We calculate the Casimir interaction between two parallel wires and between a
wire and a metall plate. The dielectric properties of the objects are described
by the plasma, Drude and perfect metal models. We find that at asymptotically
large separation interactions involving plasma wires and/or plates are
independent of the material properties, but depend on the dc conductivity
for Drude wires. Counterintuitively, at intermediate separations the
interaction involving Drude wires can become independent of . At
smaller separations, we compute the interaction numerically and observe an
approach to the proximity approximation
Collective charge fluctuations and Casimir interactions for quasi one-dimensional metals
We investigate the Casimir interaction between two parallel metallic
cylinders and between a metallic cylinder and plate. The material properties of
the metallic objects are implemented by the plasma, Drude and perfect metal
model dielectric functions. We calculate the Casimir interaction numerically at
all separation distances and analytically at large separations. The
large-distance asymptotic interaction between one plasma cylinder parallel to
another plasma cylinder or plate does not depend on the material properties,
but for a Drude cylinder it depends on the dc conductivity . At
intermediate separations, for plasma cylinders the asymptotic interaction
depends on the plasma wave length while for Drude cylinders
the Casimir interaction can become independent of the material properties. We
confirm the analytical results by the numerics and show that at short
separations, the numerical results approach the proximity force approximation
Quantum and thermal Casimir interaction between a sphere and a plate: Comparison of Drude and plasma models
We calculate the Casimir interaction between a sphere and a plate, both
described by the plasma model, the Drude model, or generalizations of the two
models. We compare the results at both zero and finite temperatures. At
asymptotically large separations we obtain analytical results for the
interaction that reveal a non-universal, i.e., material dependent interaction
for the plasma model. The latter result contains the asymptotic interaction for
Drude metals and perfect reflectors as different but universal limiting cases.
This observation is related to the screening of a static magnetic field by a
London superconductor. For small separations we find corrections to the
proximity force approximation (PFA) that support correlations between geometry
and material properties that are not captured by the Lifshitz theory. Our
results at finite temperatures reveal for Drude metals a non-monotonic
temperature dependence of the Casimir free energy and a negative entropy over a
sizeable range of separations.Comment: 11 pages, 5 figure
Elastic Lattice Polymers
We study a model of "elastic" lattice polymer in which a fixed number of
monomers is hosted by a self-avoiding walk with fluctuating length . We
show that the stored length density scales asymptotically
for large as , where is the
polymer entropic exponent, so that can be determined from the analysis
of . We perform simulations for elastic lattice polymer loops with
various sizes and knots, in which we measure . The resulting estimates
support the hypothesis that the exponent is determined only by the
number of prime knots and not by their type. However, if knots are present, we
observe strong corrections to scaling, which help to understand how an entropic
competition between knots is affected by the finite length of the chain.Comment: 10 page
Thinning of superfluid films below the critical point
Experiments on He films reveal an attractive Casimir-like force at the
bulk -point, and in the superfluid regime. Previous work has explained
the magnitude of this force at the transition and deep in the
superfluid region but not the substantial attractive force immediately below
the -point. Utilizing a simple mean-field calculation renormalized by
critical fluctuations we obtain an effective Casimir force that is
qualitatively consistent with the scaling function obtained by
collapse of experimental data.Comment: 4 page
Bone health in patients with multiple sclerosis relapses
OBJECTIVES:
To evaluate the bone health and vitamin D levels of a cohort of patients with relapses of multiple sclerosis (MS) and to propose an algorithm for the management of bone health in this patient group.
METHODS:
We prospectively studied 56 consecutive patients from our acute relapse clinic. 3 patients were excluded from analysis as they were not deemed to have experienced an acute MS relapse. Bone health was assessed with vitamin D levels and Dual Energy X-ray Absorptiometry (DEXA) scanning (10 patients failed to attend for DEXA). Statistical analyses were used to compare groups and identify predictive variables. A review of the literature led to a proposed management protocol.
RESULTS:
Pre-relapse the baseline EDSS was ≤6.5 in all subjects, and <4.0 in the majority (66%). Most received corticosteroids. 51% had low bone mineral density (BMD) as defined by a T-score less than −1.0 on DEXA scanning. Three were osteoporotic (T-score less than −2.5). Thirty one of fifty (62%) subjects were Vitamin D deficient (25(OH)D less than 50 nmol/L). A range of variables, including previous corticosteroid usage, were not significantly predictive of reduced BMD.
CONCLUSIONS:
There was a high frequency of both low BMD and Vitamin D deficiency in this cohort of relatively young and largely ambulatory patients experiencing MS relapses. Current tools, such as the WHO FRAX algorithm, are inadequate in assessing bone status and fracture risk in this patient group, predominantly as they are focused on older age groups. We propose a simple clinical management algorithm
pH-Responsive PVA-Based Nanofibers Containing GO Modified with Ag Nanoparticles: Physico-Chemical Characterization, Wound Dressing, and Drug Delivery
Site-specific drug delivery and carrying repairing agents for wound healing purposes can be achieved using the intertwined three-dimensional structure of nanofibers. This study aimed to optimize and fabricate poly (vinyl alcohol) (PVA)-graphene oxide (GO)-silver (Ag) nanofibers containing curcumin (CUR) using the electrospinning method for potential wound healing applications. Fourier Transform Infrared (FTIR) spectrophotometry, X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Dynamic Light Scattering (DLS), and zeta potential were used to characterize the nanostructures. The mechanical properties of the nanostructures were subsequently examined by tensile strength and elongation test. As shown by MIC analysis of E. coli and S. aureus bacteria, the fabricated nanofibers had superior inhibitory effects on the bacteria growth. Ag nanoparticles incorporation into the nanofibers resulted in increased loading and encapsulation efficiencies from 21% to 56% and from 61% to 86%, respectively. CUR release from PVA/GO-Ag-CUR nanofiber at pH 7.4 was prevented, while the acidic microenvironment (pH 5.4) increased the release of CUR from PVA/GO-Ag-CUR nanofiber, corroborating the pH-sensitivity of the nanofibers. Using the in vitro wound healing test on NIH 3T3 fibroblast cells, we observed accelerated growth and proliferation of cells cultured on PVA/GO-Ag-CUR nanofibers
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