Incidence et causes des blessures par piqûre d'aiguille aux niveaux mondial, régional et national:revue systématique et méta-analyse

Background: Needlestick injuries (NSIs) are one of the most serious occupational hazards for healthcare workers (HCWs). Aims: The aim of this study was to evaluate the incidence and causes of NSIs globally. Methods: A systematic review and meta-analysis of data from January 2000 to May 2020 collected from Scopus, PubMed, Embase, Web of Science, and Google Scholar. The Newcastle–Ottawa Scale was used to assess the quality of the included articles. The data obtained were analysed by R version 3/5/0, and 113 articles were retrieved. Results: There were 113 studies with a total of 525 798 HCWs. The incidence of NSIs was 43%. Africa had the highest rate of these injuries of 51%, and the World Health Organization (WHO) African Region had the highest incidence among WHO regions of 52%. Women were more frequently affected by NSIs than men. Hepatitis C virus infection was the disease most commonly transmitted via NSIs (21%). The highest rates of NSIs according to causes, devices, hospital locations, occupa-tions and procedures were for recapping of needles, needles, general wards, nurses and waste disposal, respectively. Conclusion: The incidence of NSIs is gradually decreasing. The findings of this study can contribute to improving the decision-making process for reducing NSIs in HCWs

The worldwide prevalence of anxiety in acquired immune deficiency syndrome patients: A systematic review and meta-analysis

Background: Anxiety affects social, economic, and physical aspects of daily life in patients with AIDS. Therefore, it is necessary to take preventive measures and design plans to maintain their general health. The present study was the first comprehensive systematic literature review research that examined the worldwide prevalence rate of anxiety in patients with AIDS. Methods: We searched for papers published in the English language in the major databases including Embase, PubMed, Web of Science, Scopus, Cochrane, and Google Scholar from 2000 to October 2018. There were 40 studies which found to be eligible. These studies were independently evaluated and the collected data were entered in a data extraction form, which was then analyzed by two authors and a third author if necessary. Der Simonian-Laird model was used to estimate the prevalence rate on a Forest plot at the interval confidence of 95%. Results: The total sample size was 24111, and the total number of people with anxiety was 5546. The results based on the random-effects model showed that the rate of anxiety prevalence in the patients was 25% (CI: 95%, 21% -30%) with heterogeneity of 97.9% and a significance level of p<0.001. The South America continent with a prevalence f 38% (95% CI, 34%-42%) had the highest anxiety prevalence rates and Africa with 19% (95% CI, 12% -29%) had the lowest anxiety prevalence rates. Conclusion: Based on findings, the prevalence of anxiety in developed countries was partially higher than in underdeveloped countries and the obtained mean in the present study. It can be a significant point for policymakers. Therefore, WHO and the world community should have special plans for these countries

Global systematic review and meta-analysis of health-related quality of life in Behcet’s patients

Background: Behcet’s disease (BD) is a chronic fatal illness with a relapsing remitting nature and significant organ-threatening morbidity and mortality. The aim of this research was to examine studies which were conducted on investigation of prevalence of quality of life among patients with Behcet’s disease. Methods: A total of 13 articles were extracted from four main databases including PubMed, EMBASE, Scopus, and Web of Science from the onset of 2000 to January 2021. All studies published in English with the purpose of examining quality of life (QOL) among patients with BD or investigating its main determinants were included. Results: Totally, 1137 BD patients participated in 13 studies. Based on random effect analysis, the total score of physical health-related QOL was 46.7 (95% CI=41.26 to 52.13) and the total score of mental health-related QOL was 49.01 (95% CI=43.83 to 54.18) representing a moderate level of QOL among BD patients. Furthermore, weighted effect size analyses showed a significant correlation between QOL and variables such as patients’ age, gender, disease duration and depression (pvalue: 0.00). Conclusion: As the symptoms of BD worsen over time, patients confront with more severe body pain, mobility restrictions, and difficulties in chewing, eating, speaking and swallowing which negatively affect social interactions of patients and reduce their QOL. Furthermore, depression was proved to act as a deteriorating factor for Health-Related Quality of Life (HRQOL) among BD patients. Thus, patients need to be psychologically supported by a specialized team and be informed during the course of treatment to gain useful information about the disease, treatment approaches and coping strategies

Global, regional, and national prevalence of depression among cancer patients:A systematic review and meta-analysis

This systematic review and meta-analysis aimed to provide a summary of the existing evidence on the prevalence of depression among cancer patients worldwide to assist health policymakers in adopting appropriate measures to prevent and control depression in these patients. EMBASE, Google Scholar, Scopus, PubMed, and Web of Science databases were searched for original studies published in English from January 2000 to July 2019. The studies were screened on the basis of quality and relevance criteria. The statistical analyses were conducted in the R software. Out of 182,521 cancer patients examined in 183 studies, 49,280 (~27%) had depression (95% confidence interval [CI] = 24%-30%). The highest prevalence of depression was among patients with colorectal cancer with 32% (95% CI = 20%-47%). Among countries, Pakistan with 43% (95% CI = 26%-64%), and among continents, Africa with 36% (95% CI = 29%-43%) had the highest prevalence of reported depression in cancer patients. Adjusting for sample size, the prevalence of depression among female cancer patients, 31% (95% CI = 26%-36%), was higher than men, 26% (95% CI = 21%-31%). The prevalence of depression among cancer patients is increasing by an average of 0.6% per year. The findings show higher prevalence of depression among cancer patients in underdeveloped and developing countries compared to the developed nations and the global average

Machine learning for satisficing operational decision making: A case study in blood supply chain

Machine learning (ML) has attracted recent attention in solving constrained optimization problems to reduce computational time. In this article, we employ multi-output ML models including light gradient-boosting machine (LGBM) and multilayer perceptron (MLP) to predict the solution to a constrained optimization problem, explore the impacts of selecting different loss functions, and evaluate their performance by looking at the utility of predicted decisions, i.e., the associated cost components and the feasibility of predicted solutions We implement our approach in a blood supply chain where hospitals collaborate on transshipment to meet demand. We use demand distributions fitted to real data to evaluate the performance of the predictive models by analysis of the utility of forecasts, including total cost, inventory holding, transshipment, outdated unit, and shortage costs associated with predicted decisions. The results of our case study show that an LGBM model with the mean absolute deviation loss function provides solutions with only 2% higher total cost than a stochastic optimization model. Compared to an empirical policy, it could reduce transshipment and shortage costs by 23% and 6%, respectively. Therefore, altering the loss function of ML models can provide appropriate solutions to optimization problems, and various loss functions should be probed accordingly.</p

Disruption risk management in service-level agreements

© 2020 Informa UK Limited, trading as Taylor & Francis Group. This paper studies the impact of capacity/inventory disruption on a supplier\u27s cost, where the supplier has heterogeneous service level agreements (SLAs) in place with multiple customers (retailers). We compare three capacity allocation policies in the presence of supply disruption, with both full and partial disruption cases investigated. The results show that the two-stage policy outperforms other capacity allocation policies when a disruption is anticipated and that partial disruption is more manageable than full disruption in terms of meeting the SLAs. Furthermore, the supplier is better off to negotiate a longer performance review period assuming the penalty per time unit is fixed. This result is contrary to findings in the literature for SLAs when there is no consideration of disruption. The insights from this study can assist suppliers in determining their capacity level, making capacity-related decisions such as locations of warehouses or production sites, in allocating capacity to customers and in negotiating SLA terms such as the performance review period length and penalty rates

Global prevalence of depression in HIV/AIDS:A systematic review and meta-analysis

Introduction: The incidence of some fatal diseases, including HIV/AIDS, accompanied by depression has become a significant concern in developed, developing and underdeveloped countries. A great deal of time and money are spent on controlling and reducing the complications of this infection across the world. Accordingly, the main purpose of this study was to clarify the global prevalence rate of depression in patients living with HIV/AIDS via a systematic review and meta-analysis. Methodology: All articles in English, published between 2000 and 2018, were systematically searched from the original databases of Web of Science, PubMed, Scopus, Cochrane Library, Google Scholar and Embase. As a result, a total of 118 articles were identified. Results: The total sample size in these articles was 51143 people, and the number of patients suffering from moderate and severe levels of depression was 14 942. The results of the analysis based on the random-effects (DerSimonian and Laird) model revealed that the prevalence rate of depression in patients with HIV/AIDS was 31% (95% CI 28% to 34%), with a 98% heterogeneity index which was reported significant. Meanwhile, the highest prevalence rate of depression based on continent was in South America at 44% (95% CI 35% to 53%) and the lowest rate was in Europe at 22% (95% CI 17% to 27%). Conclusion: In general, there was a higher prevalence rate of depression in developing and underdeveloped countries than in developed countries, which could be attributed to the advancement of science and the possibilities for early diagnosis of this syndrome. Trial registration number: CRD42019119137

Global Quality of Life in HIV/AIDS Patients: A Systematic Review and Meta-Analysis

Background: Acquired immunodeficiency syndrome (AIDS) caused by the human immunodeficiency virus (HIV) is known as one of the most chronic conditions, having significant effects on physical and mental health status in infected individuals, and thus reducing their quality of life (QoL).Methods: I n t his s ystematic r eview, t he d ata w ere i nitially collected from the databases of Scopus, PubMed, Embase, Web of Science, and Google Scholar from January 2000 to September 2020 based on the inclusion and exclusion criteria of the study. The data were then analyzed by using the R software.Results: A total number of 25 research articles addressing the QoL in 5,952 HIV/AIDS patients were evaluated using three valid questionnaires, including the Medical Outcomes Study HIV Health Survey (MOS-HIV), the 36-Item Short Form Health Survey (SF-36), and the World Health Organization Quality of Life in HIV-Infected Persons (WHOQoL-HIV). Based on the MOS-HIV, the SF-36, and the WHOQoL-HIV questionnaires, the QoL mean scores in HIV/AIDS patients were 51.80 (49.4- 54.57), 54.81 (52.68-56.93), and 13.62 (11.97-15.26), respectively. In addition, the physical items gained a higher mean score than the mental ones in all the questionnaires. The QoL showed higher mean scores in the SF-36 and the WHOQoL-HIV questionnaires in Africa, except for the MOS-HIV questionnaire, which had the highest mean score in North America.Conclusion: Overall, the QoL in HIV/AIDS patients in this study was acceptable, even though further changes and studies are still required to support the findings