Characterization of Central Asian Strain1 using mycobacterial interspersed repetitive unit genotyping-2

<p><b>Copyright information:</b></p><p>Taken from "Characterization of Central Asian Strain1 using mycobacterial interspersed repetitive unit genotyping"</p><p>http://www.biomedcentral.com/1471-2180/7/76</p><p>BMC Microbiology 2007;7():76-76.</p><p>Published online 9 Aug 2007</p><p>PMCID:PMC1988810.</p><p></p>ics software using the unweighted pair group method. The 178 CAS1 strains studied showed an overall homology of >70%. No MIRU clusters were observed between any of the 189 'unique' strains studied

Characterization of Central Asian Strain1 using mycobacterial interspersed repetitive unit genotyping-1

<p><b>Copyright information:</b></p><p>Taken from "Characterization of Central Asian Strain1 using mycobacterial interspersed repetitive unit genotyping"</p><p>http://www.biomedcentral.com/1471-2180/7/76</p><p>BMC Microbiology 2007;7():76-76.</p><p>Published online 9 Aug 2007</p><p>PMCID:PMC1988810.</p><p></p>cs software (Applied Maths). The strains included 29 CAS1 and 49 'unique' strains. * denotes CAS1 strains exhibiting heterogeneous IS-RFLP profiles

Characterization of Central Asian Strain1 using mycobacterial interspersed repetitive unit genotyping-0

<p><b>Copyright information:</b></p><p>Taken from "Characterization of Central Asian Strain1 using mycobacterial interspersed repetitive unit genotyping"</p><p>http://www.biomedcentral.com/1471-2180/7/76</p><p>BMC Microbiology 2007;7():76-76.</p><p>Published online 9 Aug 2007</p><p>PMCID:PMC1988810.</p><p></p>ics software using the unweighted pair group method. The 178 CAS1 strains studied showed an overall homology of >70%. No MIRU clusters were observed between any of the 189 'unique' strains studied

Diagnostic modality used for confirmation of tuberculosis.

<p>Note: Primary diagnostic modality used diagnosis of tuberculosis.</p>*<p>Criteria for disease category given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#s4" target="_blank">material and methods</a>.</p>¶<p>Imaging tests included chest×rays for pulmonary patients, CT scan and or MRI for disseminated disease.</p

Demographic characteristics of TB Patients and Controls.

<p><b>Note:</b> Patient stratification is as given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#s4" target="_blank">Materials and Methods</a>. Abbreviations for groups are given in brackets. TBA included 10 previously treated patients.</p

Genotype frequencies in healthy controls and different clinical forms of tuberculosis (TB).

<p>Note: Patient stratification is given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#s4" target="_blank">Materials and Methods</a>. N for each group given in brackets. Abbreviations used as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#pone-0004778-t001" target="_blank">Table 1</a>. Number (frequency) of genotypes is indicated. Pearson chi analysis was carried to determine the significance of differences.</p><p>All significant p values are indicated in bold. P approaching significance is given in italics. <i>p</i><0.05 is considered significant.</p

Relationship of IFNγ and IL10 SNPs with mycobacterial antigen induced cytokine secretion.

<p>Whole blood from TB not affected (TBNA) Tuberculin skin test positive donors was stimulated with <i>M. tuberculosis</i> culture filtrate (CF) proteins [5 µg/ml] and supernatants tested at 2 days for IL10 secretion and day 5 for IFNγ secretion using ELISA method as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#s4" target="_blank">material and methods</a>. Results are expressed as pg/ml after deducting secretion in un-stimulated whole blood.</p

Genotype combination in relation to disease severity.

<p>Genotype combination in relation to disease severity.</p

Differences in allele frequencies in healthy controls and tuberculosis patients

<p>Note: Patient stratification is given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#s4" target="_blank">material and methods</a>. N for each group is given in brackets. Abbreviations used as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#pone-0004778-t001" target="_blank">Table 1</a>.</p

Differential LPS-induced CXCL9 and CCL2 in limited and severe TB.

<p>Whole blood cells were stimulated with LPS at 1 µg/ml and CXCL9 measured in cell supernatants harvested at 2 days post-stimulation. All other parameters as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0005158#pone-0005158-g001" target="_blank">Fig. 1</a>. A. CXCL9 and B. CCL2.</p