Avaliação da fragilidade de idosos em tratamento quimioterápico ambulatorial

Aim: to characterize and verify the fragility of the elderly in outpatient chemotherapy treatment in a university hospital of southern Brazil, and to identify the association between fragility and the following variables: chemotherapeutic effect, treatment time and selfreported diseases. Method: cross-sectional study conducted with 70 elderly in the chemotherapy outpatient, from August to September 2014 by means of Edmonton Frail Scale and characterization form. Results: fifty percent did not present fragility, 31.4% were apparently vulnerable and 18.6% had some level of fragility. Among the frail elderly, 15.7% had mild fragility, 1.4% moderate and 1.4% severe. The association between frailty and self-reported diseases, time of treatment and chemotherapeutic effects was not statistically significant. Conclusion: it was point to applicability of the scale to identify predisposing factors for the fragility syndrome and to enable preventive actions for the elderly in chemotherapeutic treatmentObjetivo: caracterizar y verificar la fragilidad de los ancianos en tratamiento de quimioterapia ambulatoria, en un hospital universitario, en el sur de Brasil, e identificar la asociación entre la fragilidad y las variables de efecto quimioterapéutico, relacionadas al tiempo de tratamiento y la enfermedad auto reporte. Método: estudio transversal realizado con 70 ancianos de un ambulatorio de quimioterapia, entre agosto y septiembre de 2014, a través de la Edmonton Frail Scale y forma de caracterización. Resultados: 50% no presentaron fragilidad, 31,4% eran aparentemente vulnerables y 18,6% tenía algún nivel de fragilidad. Entre los ancianos frágiles 15,7% tenían una fragilidad leve, 1,4% moderada y 1,4% severa. La asociación entre fragilidad y enfermedades auto referidas, y tiempo de tratamiento y efectos quimioterápicos no presentó significancia estadística. Conclusión: se observó la aplicabilidad de la escala para identificar factores predisponentes para el síndrome de fragilidad y viabilizar acciones preventivas a los ancianos en tratamiento quimioterápico.Objetivo: caracterizar e verificar a fragilidade de idosos em tratamento quimioterápico ambulatorial em um Hospital Universitário da região Sul do Brasil e, identificar a associação entre a fragilidade e as variáveis: efeito quimioterápico, tempo de tratamento e doenças autorreferidas. Método: estudo transversal desenvolvido com 70 idosos em um ambulatório de quimioterapia, de agosto a setembro de 2014, por meio da Edmonton Frail Scale e do formulário de caracterização. As análises estatísticas foram realizadas no programa Statistical Package for the Social Sciences versão 21. Resultados: houve predomínio de idosos do sexo masculino (61,4%), casados (62,8%), com ensino fundamental incompleto (71,4%), com renda mensal de até dois salários mínimos (82,8%) e a metade não apresentava fragilidade (50%). Conclusão: as variáveis analisadas não apresentaram significância, portanto não representam um fator de risco para a fragilidade de idosos em tratamento quimioterápico

Design of a Two-level Adaptive Multi-Agent System for Malaria Vectors driven by an ontology

<p>Abstract</p> <p>Background</p> <p>The understanding of heterogeneities in disease transmission dynamics as far as malaria vectors are concerned is a big challenge. Many studies while tackling this problem don't find exact models to explain the malaria vectors propagation.</p> <p>Methods</p> <p>To solve the problem we define an Adaptive Multi-Agent System (AMAS) which has the property to be elastic and is a two-level system as well. This AMAS is a dynamic system where the two levels are linked by an Ontology which allows it to function as a reduced system and as an extended system. In a primary level, the AMAS comprises organization agents and in a secondary level, it is constituted of analysis agents. Its entry point, a User Interface Agent, can reproduce itself because it is given a minimum of background knowledge and it learns appropriate "behavior" from the user in the presence of ambiguous queries and from other agents of the AMAS in other situations.</p> <p>Results</p> <p>Some of the outputs of our system present a series of tables, diagrams showing some factors like Entomological parameters of malaria transmission, Percentages of malaria transmission per malaria vectors, Entomological inoculation rate. Many others parameters can be produced by the system depending on the inputted data.</p> <p>Conclusion</p> <p>Our approach is an intelligent one which differs from statistical approaches that are sometimes used in the field. This intelligent approach aligns itself with the distributed artificial intelligence. In terms of fight against malaria disease our system offers opportunities of reducing efforts of human resources who are not obliged to cover the entire territory while conducting surveys. Secondly the AMAS can determine the presence or the absence of malaria vectors even when specific data have not been collected in the geographical area. In the difference of a statistical technique, in our case the projection of the results in the field can sometimes appeared to be more general.</p

Avaliação da fragilidade de idosos em tratamento quimioterápico ambulatorial

Aim: to characterize and verify the fragility of the elderly in outpatient chemotherapy treatment in a university hospital of southern Brazil, and to identify the association between fragility and the following variables: chemotherapeutic effect, treatment time and selfreported diseases. Method: cross-sectional study conducted with 70 elderly in the chemotherapy outpatient, from August to September 2014 by means of Edmonton Frail Scale and characterization form. Results: fifty percent did not present fragility, 31.4% were apparently vulnerable and 18.6% had some level of fragility. Among the frail elderly, 15.7% had mild fragility, 1.4% moderate and 1.4% severe. The association between frailty and self-reported diseases, time of treatment and chemotherapeutic effects was not statistically significant. Conclusion: it was point to applicability of the scale to identify predisposing factors for the fragility syndrome and to enable preventive actions for the elderly in chemotherapeutic treatmentObjetivo: caracterizar y verificar la fragilidad de los ancianos en tratamiento de quimioterapia ambulatoria, en un hospital universitario, en el sur de Brasil, e identificar la asociación entre la fragilidad y las variables de efecto quimioterapéutico, relacionadas al tiempo de tratamiento y la enfermedad auto reporte. Método: estudio transversal realizado con 70 ancianos de un ambulatorio de quimioterapia, entre agosto y septiembre de 2014, a través de la Edmonton Frail Scale y forma de caracterización. Resultados: 50% no presentaron fragilidad, 31,4% eran aparentemente vulnerables y 18,6% tenía algún nivel de fragilidad. Entre los ancianos frágiles 15,7% tenían una fragilidad leve, 1,4% moderada y 1,4% severa. La asociación entre fragilidad y enfermedades auto referidas, y tiempo de tratamiento y efectos quimioterápicos no presentó significancia estadística. Conclusión: se observó la aplicabilidad de la escala para identificar factores predisponentes para el síndrome de fragilidad y viabilizar acciones preventivas a los ancianos en tratamiento quimioterápico.Objetivo: caracterizar e verificar a fragilidade de idosos em tratamento quimioterápico ambulatorial em um Hospital Universitário da região Sul do Brasil e, identificar a associação entre a fragilidade e as variáveis: efeito quimioterápico, tempo de tratamento e doenças autorreferidas. Método: estudo transversal desenvolvido com 70 idosos em um ambulatório de quimioterapia, de agosto a setembro de 2014, por meio da Edmonton Frail Scale e do formulário de caracterização. As análises estatísticas foram realizadas no programa Statistical Package for the Social Sciences versão 21. Resultados: houve predomínio de idosos do sexo masculino (61,4%), casados (62,8%), com ensino fundamental incompleto (71,4%), com renda mensal de até dois salários mínimos (82,8%) e a metade não apresentava fragilidade (50%). Conclusão: as variáveis analisadas não apresentaram significância, portanto não representam um fator de risco para a fragilidade de idosos em tratamento quimioterápico

Urinary and Serum Concentration of Deoxynivalenol (DON) and DON Metabolites as an Indicator of DON Contamination in Swine Diets

Pig health is impaired and growth performance is reduced when exposed to deoxynivalenol (DON). The measurement of DON in individual feedstuffs and complete swine diets is variable because of the inconsistent distribution of mycotoxins in feed and the difficulties in obtaining representative samples. We investigated whether measuring DON and its metabolites in biological samples could be used as a predictor of DON ingestion by pigs. Blood samples were collected between 3 and 4 h after the morning meal and urine samples were quantitatively collected over a 24 h period on d 40 and 82 of the study to evaluate serum and urinary content of DON and DON metabolites (iso-deoxynivalenol, DON-3-glucuronide, DON-15-glcurunide, deepoxy-deoxynivalenol, iso-deepoxy-deoxynivalenol, deepoxy-deoxynivalenol-3-glucuronide, and deepoxy-deoxynivalenol-15-glucuronide). The intake of DON was positively correlated with urinary DON output. Similarly, there was an increase in serum DON level with increasing DON intake. Overall, it was found that DON intake correlated with DON concentration in urine and blood serum when samples were collected under controlled conditions. Analyzing DON levels in urine and blood serum could be used to predict a pig&rsquo;s DON intake

Le sacré et son inscription dans l’espace à Byzance et en Occident

Le présent volume rassemble seize auteurs autour d'une thématique qui a fait l'objet de deux années de séminaire à l'Université Paris I (Panthéon- Sorbonne) dans le cadre de l'équipe doctorale d'Histoire byzantine et s'est inscrite dans tout un courant de recherches sur la spatialisation du sacré. Sans tenter d'approfondir la notion même de sacré dans le christianisme, les auteurs ont recherché comment ce sacré, par essence omniprésent, s'inscrit dans un espace précis, souvent matériellement délimité, sorte d'adaptation de sa transcendance ontologique à la finitude humaine, mais aussi aux enjeux pas uniquement spirituels de la société humaine. L'ouvrage confronte les recherches et conceptions de spécialistes d'histoire, d'histoire de l'art et d'archéologie, aussi bien du monde chrétien oriental, principalement byzantin, que de l'Occident médiéval. Contributions de Jean-Pierre Arrignon, Marie-France Auzépy, Josiane Barbier, Catherine Bortoli-Doucet, Béatrice Caseau, Marie-Hélène Congourdeau, Anne-Marie Helvétius, Catherine Jolivet-Lévy, Michel Kaplan, Elisabeth Malamut, Arietta Papaconstantinou, Jean-Pierre Sodini, Alice-Mary Talbot, P. P. ToloÄko, Cécile Treffort, Michel Zimmermann

Images du corps dans le monde hindou

Comment se représente-t-on le corps dans le monde hindou ? Comment y est-il pensé et décrit ? Alors même que des recherches anthropologiques sur la société indienne l’ont placé au fondement des rapports sociaux entre castes, ou à la base des conceptions sur l’impureté, le corps n’avait jusqu’ici guère été étudié en lui-même. Aussi ce livre s’attache-t-il à restituer la multiplicité et la complexité de ses représentations, depuis la période védique ancienne jusqu’à nos jours, à travers l’iconographie, les images verbales, les pratiques corporelles d’exception ou les interactions quotidiennes. Quatre principaux domaines sont abordés. Après des approches historiques et épistémologiques mettant à jour diverses logiques de description et d’utilisation référentielle du corps, celui-ci est envisagé dans sa dimension ésotérique comme microcosme, support et objet d'ensembles complexes de représentations et de pratiques, en particulier du yoga et des tantras. Puis, divers aspects de son élaboration visuelle, gestuelle et perceptive sont examinés, dans le cadre de rituels de dévotion, de chants de mariage, de macérations ascétiques ou du cinéma populaire hindi. Enfin, une dernière partie analyse en quoi le corps est un lieu d'inscription de rapports sociaux variés. Des constantes émergent, qui montrent que si toutes ces représentations coexistent et se juxtaposent, elles n’en sont pas moins hiérarchisées, comme le sont les corps eux-mêmes. L'ensemble des contributions réunies ne se limite pas aux spéculations savantes. Il s'appuie tout autant sur les traditions orales, sur les règles légales, sur l’observation contemporaine des pratiques effectives - bref, sur la diversité des faits et des paroles qui manifestent, en Inde, les multiples réalités des corps