FedSelect: Customized Selection of Parameters for Fine-Tuning during Personalized Federated Learning

Recent advancements in federated learning (FL) seek to increase client-level performance by fine-tuning client parameters on local data or personalizing architectures for the local task. Existing methods for such personalization either prune a global model or fine-tune a global model on a local client distribution. However, these existing methods either personalize at the expense of retaining important global knowledge, or predetermine network layers for fine-tuning, resulting in suboptimal storage of global knowledge within client models. Enlightened by the lottery ticket hypothesis, we first introduce a hypothesis for finding optimal client subnetworks to locally fine-tune while leaving the rest of the parameters frozen. We then propose a novel FL framework, FedSelect, using this procedure that directly personalizes both client subnetwork structure and parameters, via the simultaneous discovery of optimal parameters for personalization and the rest of parameters for global aggregation during training. We show that this method achieves promising results on CIFAR-10.Comment: We are still expanding this wor

Probing phase transition in neutron stars via the crust-core interfacial mode

Gravitational waves emitted from the binary neutron star (BNS) systems can carry information about the dense matter phase in these compact stars. The crust-core interfacial mode is an oscillation mode in a neutron star and it depends mostly on the equation of the state of the matter in the crust-core transition region. This mode can be resonantly excited by the tidal field of an inspiraling-in BNS system, thereby affecting the emitted gravitational waves, and hence could be used to probe the equation of state in the crust-core transition region. In this work, we investigate in detail how the first-order phase transition inside the neutron star affects the properties of the crust-core interfacial mode, using a Newtonian fluid perturbation theory on a general relativistic background solution of the stellar structure. Two possible types of phase transitions are considered: (1) the phase transitions happen in the fluid core but near the crust-core interface, which results in density discontinuities; and (2) the strong interaction phase transitions in the dense core (as in the conventional hybrid star case). These phase transitions' impacts on interfacial mode properties are discussed. In particular, the former phase transition has a minor effect on the M-R relation and the adiabatic tidal deformability, but can significantly affect the interfacial mode frequency and thereby could be probed using gravitational waves. For the BNS systems, we discuss the possible observational signatures of these phase transitions in the gravitational waveforms and their detectability. Our work enriches the exploration of the physical properties of the crust-core interfacial mode and provides a promising method for probing the phase transition using the seismology of a compact star.Comment: 18 pages, 14 figure

Surgical outcome of hepatocellular carcinoma patients with biliary tumor thrombi

<p>Abstract</p> <p>Background</p> <p>To investigate the surgical outcome of hepatocellular carcinoma (HCC) patients with biliary tumor thrombi (BTT).</p> <p>Methods</p> <p>Surgical outcome of 27 HCC patients with BTT (group I) were compared with randomly selected HCC patients without BTT (group II; n = 270).</p> <p>Results</p> <p>One patient in group I died of hepatic failure within 30 days after resection. The 1-, 3- and 5-year cumulative survival rates of group I were 70.3%, 25.9%, and 7.4%, respectively; these were significantly lower than those of group II (90.6%, 54.0%, and 37.7%) (<it>P <</it>0.001). The rates of early recurrence (≤ 1 year) after resection were significantly higher in group I than group II (70.3% vs. 34.8%) (<it>P </it>< 0.001).</p> <p>Conclusion</p> <p>HCC patients with BTT had a worse prognosis after resection than those without BTT. Resection should be considered for these tumors given the lack of effective alternative therapies.</p

Non-Markovian Dynamics of Entanglement for Multipartite Systems

Entanglement dynamics for a couple of two-level atoms interacting with independent structured reservoirs is studied using a non-perturbative approach. It is shown that the revival of atom entanglement is not necessarily accompanied by the sudden death of reservoir entanglement, and vice versa. In fact, atom entanglement can revive before, simultaneously or even after the disentanglement of reservoirs. Using a novel method based on the population analysis for the excited atomic state, we present the quantitative criteria for the revival and death phenomena. For giving a more physically intuitive insight, the quasimode Hamiltonian method is applied. Our quantitative analysis is helpful for the practical engineering of entanglement.Comment: 10 pages and 4 figure

Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review

Background: This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC). Methods: Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied. An extensive database literature search was performed to obtain for all relevant studies. Results: In our series, there were no perioperative deaths during repeat hepatectomy for recurrent HCC. Patients survival after repeat hepatectomy were similar to 429 patients undergoing initial hepatectomy. A computerized search of the Medline and PubMed databases found 29 retrospective studies providing relevant data in 1149 patients were included for appraisal and data extraction. After the repeat hepatectomy, postoperative morbidity ranged from 6.2% to 68.2% with a median per cohort of 23.5 per cent. There were 7 perioperative deaths (0.7 per cent of 993 for whom mortality data were provided). The overall median survival ranged from 21 to 61.5 months, with 1 -, 3 -, and 5-year survival of 69.0% to 100%, 21.0% to 87.0%, and 25.0% to 87.0%, respectively. Conclusions: Repeat hepatectomy can be performed safely and is associated with long-term survival in a subset of patients with recurrent HCC. However, the findings have to be carefully interpreted due to the lower level of evidence. A randomized controlled study is needed to compare repeat hepatectomy and other modalities for recurrent HCC

Effects of Cutting Intensity on Soil Physical and Chemical Properties in a Mixed Natural Forest in Southeastern China

The mixed Chinese fir (Cunninghamia lanceolata (Lamb.) Hook.), Masson’s pine (Pinus massoniana Lamb.), and hardwood forest is a major forest type in China and of national and international importance in terms of its provision of both timber and ecosystem services. However, over-harvesting has threatened its long-term productivity and sustainability. We examined the impacts of timber harvesting intensity on soil physical and chemical properties 10 and 15 years after cutting using the research plots established with a randomized block design. We considered five treatments, including clear cutting and low (13.0% removal of growing stock volume), medium (29.1%), high (45.8%), and extra-high (67.1) intensities of selective cutting with non-cutting as the control. The impact on overall soil properties derived from principal component analysis showed increasing with a rise in cutting intensity, and the most critical impact was on soil nutrients, P and K in particular. Soil nutrient loss associated with timber harvesting even at a low cutting intensity could lead to nutrient deficits in this forest although most of the soil physical properties could be recovered under the low and medium intensities of cutting. These results indicate that clear cutting and the selective cutting of extra-high and high intensities should be avoided in this type of forest in the region

The relationship between Cho/NAA and glioma metabolism: implementation for margin delineation of cerebral gliomas

BACKGROUND: The marginal delineation of gliomas cannot be defined by conventional imaging due to their infiltrative growth pattern. Here we investigate the relationship between changes in glioma metabolism by proton magnetic resonance spectroscopic imaging ((1)H-MRSI) and histopathological findings in order to determine an optimal threshold value of choline/N-acetyl-aspartate (Cho/NAA) that can be used to define the extent of glioma spread. METHOD: Eighteen patients with different grades of glioma were examined using (1)H-MRSI. Needle biopsies were performed under the guidance of neuronavigation prior to craniotomy. Intraoperative magnetic resonance imaging (MRI) was performed to evaluate the accuracy of sampling. Haematoxylin and eosin, and immunohistochemical staining with IDH1, MIB-1, p53, CD34 and glial fibrillary acidic protein (GFAP) antibodies were performed on all samples. Logistic regression analysis was used to determine the relationship between Cho/NAA and MIB-1, p53, CD34, and the degree of tumour infiltration. The clinical threshold ratio distinguishing tumour tissue in high-grade (grades III and IV) glioma (HGG) and low-grade (grade II) glioma (LGG) was calculated. RESULTS: In HGG, higher Cho/NAA ratios were associated with a greater probability of higher MIB-1 counts, stronger CD34 expression, and tumour infiltration. Ratio threshold values of 0.5, 1.0, 1.5 and 2.0 appeared to predict the specimens containing the tumour with respective probabilities of 0.38, 0.60, 0.79, 0.90 in HGG and 0.16, 0.39, 0.67, 0.87 in LGG. CONCLUSIONS: HGG and LGG exhibit different spectroscopic patterns. Using (1)H-MRSI to guide the extent of resection has the potential to improve the clinical outcome of glioma surgery