Design and application of coal mine intelligent warehousing and logistics transportation management system based on Internet of Things

In order to slove the problems of backward technology and low efficiency existed in warehousing and logistics transportation management of coal enterprises, a coal mine intelligent warehousing and logistics transportation management system based on Internet of Things was designed. The system adopts technologies of Internet of Things and RFID, and achieves precise management of cargo warehousing, increases storage capacity, warehouse utilization and speed of entry-and-exit of cargoes. Meanwhile, the system can realize closed-loop management of distribution, transportation and recycling of goods and materials in the whole process

Efficient three-dimensional high-resolution simulations of flow fields around cylinders

Few works use the fully three-dimensional computational fluid dynamic method to simulate the flow fields around the marine pipes with large aspect ratios due to the huge computation cost. In the present work, an operator-splitting method is used to efficiently solve the three-dimensional Reynolds Average Navier–Stokes governing equations of the fluid flow around pipes by separating the problem as a combination of a two-dimensional problem in the horizontal plane and an one-dimensional problem in the vertical direction. A second order total variation diminishing finite volume method is used to solve the model. The precision of the present model is validated by comparing the present numerical results of two typical three-dimensional cases with the available experimental and numerical results. The simulation results with a commercial software are also included in the comparison and the present model shows a higher performance in terms of computational time. Keywords: CFD, Cylinder, Cube, Operator-splitting, TVD, Three-dimensiona

Dietary supplementation of teprenone potentiates thermal and hypoxia tolerance as well as cellular stress protection of Epinephelus coioides juveniles reared under multiple stressors

The present study was carried out to delineate the effect of teprenone on thermal and hypoxia tolerance and antioxidative status of Epinephelus coioides juveniles reared under multiple stressors. Four groups of fish averaging 10.0 +/- 2 g, body length of 7.5 +/- 0.5 cm were randomly distributed in 16 fiberglass tanks in triplicates. A basal diet without teprenone was used as a control (C), and the other three diets were prepared by adding 100 mg teprenone (T1), 200 mg teprenone (T2) and 400 mg teprenone (T3) per kg of diet. After 15 days of feeding, teprenone was shown to be a potent inducer of antioxidant activity. The induction of antioxidant status was associated with the generation of resistance in E. coioides against subsequent thermal or hypoxia stress at 100 and 200 mg/kg teprenone incorporation in the diet. Our results also provide new insight into the mode of antioxidant action of teprenone, in which initial generation of antioxidant enzyme activity by the compound plays a key role. Overall results add new information about the bioactivity of teprenone and advanced our knowledge of this compound as a potential prophylactic agent to maintain homeostasis in fish against thermal stress and hypoxia

Design of automation control system of fully-mechanized coal face

In order to realize collaborative automation running of equipments on fully-mechanized coal face, an automation control system of fully-mechanized coal face was designed, composition and function realization of three machine control system, belt conveyor control system, coal shearer control system, electro-hydraulic control system of hydraulic support and pump station control system were introduced. Application of the automation control system of fully-mechanized coal face realizes comprehensive information integration of the subsystems, and centralized equipment control of fully-mechanized coal face through centralized control system

The habitat differentiation, dynamics and functional potentials of bacterial and micro-eukaryotic communities in shrimp aquaculture systems with limited water exchange

Microbes are important in not only driving matter cycling, modulating water quality, but also serving as food for animals in intensive aquaculture systems, in which artificial substrates in combination of biofloc technology can be applied to strengthen microbial values and animal production. However, the influence of micro-habitats created by these practices on water quality and microbial diversity and dynamics remains poorly understood. In this study, samples of three micro-habitats, the biofilms formed on immersed meshes, the suspended macro -aggregates, and the pond water were collected from limited-water-exchange ponds for rearing Litopenaeus van-namei during a period of 80 days. Using high-throughput sequencing of 16S and 18S rRNA genes and statistical analyses, we found that the community structures of both bacteria and micro-eukaryotes were similar between biofilms and macro-aggregates (ANOVA, P > 0.05), but significantly different from those in the water (P 0.05). Functionally, microbes in both biofilms and macro-aggregates exhibited higher potentials of organic matter degradation and nitrogen removal, supporting the usefulness of application of biofloc technology and biofilms in recycling waste and nutrients in the shrimp ponds with limited water exchange

Dietary teprenone enhances non-specific immunity, antioxidative response and resistance to hypoxia induced oxidative stress in Lateolabrax maculatus

Persistent hypoxic or low-oxygen conditions in aquatic systems are becoming more frequent worldwide, causing large-scale mortalities to the aquaculture animals. Hence, it would be of great benefit to search for natural compounds that are clinically safe, yet able to induce host health and antioxidant defence system. In the experiment, Lateolabrax maculatus were fed with ketone compound teprenone and subsequently exposed to hypoxia condition. Afterwards, the effect of teprenone on the antioxidative response, non-specific immunity and hypoxia induced oxidative stress were investigated. We found that dietary supplementation of teprenone at 200 mg/kg (HT200), 400 mg/kg (HT400) and 800 mg/kg (HT800) significantly increase the total antioxidant capacity (T-AOC) during hypoxia stress. While, lower values of malondialdehyde (MDA) content, an indicator of oxidative stress, were recorded in teprenone supplemented groups. In addition, upregulation of non-specific immune parameters including lysozyme (LZM), Hsp70 and Hsp90 was observed in L.maculatus. We further demonstrated that teprenone supplementation protects L.maculatus from hypoxia and oxidative stress generated apoptosis. The pro-apoptotic signalling molecules, i.e., cytochrome C (Cty-C), caspase-9 and caspase-3 production were significantly decreased in response to teprenone supplementation during the hypoxia stress. In contrast, the anti-apoptotic response, BCL-2 gene expression, was significantly increased. We have shown that dietary teprenone induces innate immunity and antioxidative response and protects L.maculatus against hypoxia induced-oxidative stress and apoptosis; therefore, suggesting their possible role to manage the stressful condition, in particular, hypoxia stress in aquaculture

Antithermal quenching and multiparametric temperature sensing from Mn2+/Tb3+‐codoped ca2LaTaO6 phosphor

Luminescence thermometry plays significant roles in various fields including industrial production, environmental detection, aerospace, and medicine. However, its accuracy improvement remains highly challenging due to the thermal quenching effect of phosphors. Herein, for the first time, a thermal‐activated electron compensation Mn2+‐ and Tb3+‐codoped Ca2LaTaO6 phosphor is developed for multiparametric temperature sensing with tunable emission of Mn2+ and antithermal quenching emission of Tb3+, leading to excellent accuracy at high temperatures. By virtue of the deep electron trap states induced by Mn2+ dopant, the electrons in the deep trap can be thermally activated at high temperatures, which can replenish the attenuated Tb3+ emission caused by thermal quenching, thus bringing out the antithermal quenching phenomenon. On account of the prominent emission properties, the luminescence intensity ratio (LIR) readout and lifetime‐based thermometry are designed, providing a maximum relative sensitivity SR of 3.603% and 1.941% K−1, respectively. Multiparametric temperature sensing and novel data analysis are also employed to further improve the accuracy of the luminescence thermometer. The outstanding relative thermal sensitivity ranging from 8.72% to 16.11% K−1 and temperature uncertainty order of 10−3 are achieved. These results demonstrate that the designed Ca2LaTaO6:Mn2+/Tb3+ phosphor material is a promising thermal‐sensing candidate

G-quadruplexes promote the motility in MAZ phase-separated condensates to activate CCND1 expression and contribute to hepatocarcinogenesis

Abstract G-quadruplexes (G4s) can recruit transcription factors to activate gene expression, but detailed mechanisms remain enigmatic. Here, we demonstrate that G4s in the CCND1 promoter propel the motility in MAZ phase-separated condensates and subsequently activate CCND1 transcription. Zinc finger (ZF) 2 of MAZ is a responsible for G4 binding, while ZF3-5, but not a highly disordered region, is critical for MAZ condensation. MAZ nuclear puncta overlaps with signals of G4s and various coactivators including BRD4, MED1, CDK9 and active RNA polymerase II, as well as gene activation histone markers. MAZ mutants lacking either G4 binding or phase separation ability did not form nuclear puncta, and showed deficiencies in promoting hepatocellular carcinoma cell proliferation and xenograft tumor formation. Overall, we unveiled that G4s recruit MAZ to the CCND1 promoter and facilitate the motility in MAZ condensates that compartmentalize coactivators to activate CCND1 expression and subsequently exacerbate hepatocarcinogenesis

Mn⁴⁺ activated phosphors in photoelectric and energy conversion devices

Owing to their high luminous efficiency and tunable emission in both red light and far-red light regions, Mn4+ ion-activated phosphors have appealed significant interest in photoelectric and energy conversion devices such as white light emitting diode (W-LED), plant cultivation LED, and temperature thermometer. Up to now, Mn4+ has been widely introduced into the lattices of various inorganic hosts for brightly red-emitting phosphors. However, how to correlate the structure-activity relationship between host framework, luminescence property, and photoelectric device is urgently demanded. In this review, we thoroughly summarize the recent advances of Mn4+ doped phosphors. Meanwhile, several strategies like co-doping and defect passivation for improving Mn4+ emission are also discussed. Most importantly, the relationship between the protocols for tailoring the structures of Mn4+ doped phosphors, increased luminescence performance, and the targeted devices with efficient photoelectric and energy conversion efficiency is deeply correlated. Finally, the challenges and perspectives of Mn4+ doped phosphors for practical applications are anticipated. We cordially anticipate that this review can deliver a deep comprehension of not only Mn4+ luminescence mechanism but also the crystal structure tailoring strategy of phosphors, so as to spur innovative thoughts in designing advanced phosphors and deepening the applications.</p

Emerging heterostructured C₃N₄ photocatalysts for photocatalytic environmental pollutant elimination and sterilization

Photocatalysis is deemed a highly prominent technology to solve environmental problems such as pollution, CO2 emission and bacterial contamination. As an important photocatalyst, g-C3N4 has attracted a great amount of attention in environmental remediation owing to its good stability, excellent light response, low cost and environmentally friendly properties. However, the pristine g-C3N4 photocatalyst generally suffers from serious photoinduced charge carrier recombination, poor surface active sites, and insufficient visible light harvesting, thereby leading to unsatisfactory photocatalytic performance. Heterostructured C3N4 photocatalysts have recently become a research focus in environmental fields thanks to their fast photoexcited electron-hole pair dissociation, broadened visible light response range, and sufficient photoredox capability. Herein, we critically review the up-to-date developments of heterostructured C3N4 photocatalysts in organic pollutant elimination, heavy metal ion reduction, CO2 conversion and bacterial inactivation. Meanwhile, the strategies for constructing efficient C3N4 based heterostructures with enhanced environmental photocatalytic capability are thoroughly described, which should help readers to quickly acquire in-depth knowledge and to inspire new concepts in heterostructure engineering. Finally, the challenges and opportunities in fabricating heterostructured C3N4 photocatalysts for large-scale and commercial applications are discussed to give a clear study direction in this field.</p