Sound speed of a Bose-Einstein condensate in an optical lattice

The speed of sound of a Bose-Einstein condensate in an optical lattice is studied both analytically and numerically in all three dimensions. Our investigation shows that the sound speed depends strongly on the strength of the lattice. In the one-dimensional case, the speed of sound falls monotonically with increasing lattice strength. The dependence on lattice strength becomes much richer in two and three dimensions. In the two-dimensional case, when the interaction is weak, the sound speed first increases then decreases as the lattice strength increases. For the three dimensional lattice, the sound speed can even oscillate with the lattice strength. These rich behaviors can be understood in terms of compressibility and effective mass. Our analytical results at the limit of weak lattices also offer an interesting perspective to the understanding: they show the lattice component perpendicular to the sound propagation increases the sound speed while the lattice components parallel to the propagation decreases the sound speed. The various dependence of the sound speed on the lattice strength is the result of this competition.Comment: 15pages 6 figure

Coexistence of multi-photon processes and longitudinal couplings in superconducting flux qubits

In contrast to natural atoms, the potential energies for superconducting flux qubit (SFQ) circuits can be artificially controlled. When the inversion symmetry of the potential energy is broken, we find that the multi-photon processes can coexist in the multi-level SFQ circuits. Moreover, there are not only transverse but also longitudinal couplings between the external magnetic fields and the SFQs when the inversion symmetry of potential energy is broken. The longitudinal coupling would induce some new phenomena in the SFQs. Here we will show how the longitudinal coupling can result in the coexistence of multi-photon processes in a two-level system formed by a SFQ circuit. We also show that the SFQs can become transparent to the transverse coupling fields when the longitudinal coupling fields satisfy the certain conditions. We further show that the quantum Zeno effect can also be induced by the longitudinal coupling in the SFQs. Finally we clarify why the longitudinal coupling can induce coexistence and disappearance of single- and two-photon processes for a driven SFQ, which is coupled to a single-mode quantized field.Comment: 11 pages, 6 figure

Object Picture of Quasinormal Modes for Stringy Black Holes

We study the quasinormal modes (QNMs) for stringy black holes. By using numerical calculation, the relations between the QNMs and the parameters of black holes are minutely shown. For (1+1)-dimensional stringy black hole, the real part of the quasinormal frequency increases and the imaginary part of the quasinormal frequency decreases as the mass of the black hole increases. Furthermore, the dependence of the QNMs on the charge of the black hole and the flatness parameter is also illustrated. For (1+3)-dimensional stringy black hole, increasing either the event horizon or the multipole index, the real part of the quasinormal frequency decreases. The imaginary part of the quasinormal frequency increases no matter whether the event horizon is increased or the multipole index is decreased.Comment: 4 pages, 5 figure

Broad-spectrum antimicrobial activity and improved stability of a D-Amino acid enantiomer of DMPC-10A, the designed derivative of dermaseptin truncates

DMPC-10A (ALWKKLLKK-Cha-NH2) is a 10-mer peptide derivative from the N-terminal domain of Dermaseptin-PC which has shown broad-spectrum antimicrobial activity as well as a considerable hemolytic effect. In order to reduce hemolytic activity and improve stability to endogenous enzymes, a D-amino acid enantiomer (DMPC-10B) was designed by substituting all L-Lys and L-Leu with their respective D-form amino acid residues, while the Ala1 and Trp3 remained unchanged. The D-amino acid enantiomer exhibited similar antimicrobial potency to the parent peptide but exerted lower cytotoxicity and hemolytic activity. Meanwhile, DMPC-10B exhibited remarkable resistance to hydrolysis by trypsin and chymotrypsin. In addition to these advantages, DMPC-10B exhibited an outstanding antibacterial effect against Methicillin-resistant Staphylococcus aureus (MRSA) and Klebsiella pneumoniae using the Galleria mellonella larva model and displayed synergistic activities with gentamicin against carbapenem-resistant K. pneumoniae strains. This indicates that DMPC-10B would be a promising alternative for treating antibiotic-resistant pathogens

Hole Doping Dependence of the Coherence Length in La2−xSrxCuO4La_{2-x}Sr_xCuO_4 Thin Films

By measuring the field and temperature dependence of magnetization on systematically doped $La_{2-x}Sr_xCuO_4$ thin films, the critical current density $j_c(0)$ and the collective pinning energy $U_p(0)$ are determined in single vortex creep regime. Together with the published data of superfluid density, condensation energy and anisotropy, for the first time we derive the doping dependence of the coherence length or vortex core size in wide doping regime directly from the low temperature data. It is found that the coherence length drops in the underdoped region and increases in the overdoped side with the increase of hole concentration. The result in underdoped region clearly deviates from what expected by the pre-formed pairing model if one simply associates the pseudogap with the upper-critical field.Comment: 4 pages, 4 figure

Structural phase transitions in epitaxial perovskite films

Three different film systems have been systematically investigated to understand the effects of strain and substrate constraint on the phase transitions of perovskite films. In SrTiO$_3$ films, the phase transition temperature T$_C$ was determined by monitoring the superlattice peaks associated with rotations of TiO$_6$ octahedra. It is found that T$_C$ depends on both SrTiO$_3$ film thickness and SrRuO$_3$ buffer layer thickness. However, lattice parameter measurements showed no sign of the phase transitions, indicating that the tetragonality of the SrTiO$_3$ unit cells was no longer a good order parameter. This signals a change in the nature of this phase transition, the internal degree of freedom is decoupled from the external degree of freedom. The phase transitions occur even without lattice relaxation through domain formation. In NdNiO$_3$ thin films, it is found that the in-plane lattice parameters were clamped by the substrate, while out-of-plane lattice constant varied to accommodate the volume change across the phase transition. This shows that substrate constraint is an important parameter for epitaxial film systems, and is responsible for the suppression of external structural change in SrTiO$_3$ and NdNiO$_3$ films. However, in SrRuO$_3$ films we observed domain formation at elevated temperature through x-ray reciprocal space mapping. This indicated that internal strain energy within films also played an important role, and may dominate in some film systems. The final strain states within epitaxial films were the result of competition between multiple mechanisms and may not be described by a single parameter.Comment: REVTeX4, 14 figure

Study on the structure-activity relationship of an antimicrobial peptide, Brevinin-2GUb, from the skin secretion of Hylarana guentheri

Antimicrobial peptides (AMPs) are considered potential alternatives to antibiotics due to their advantages in solving antibiotic resistance. Brevinin-2GUb, which was extracted from the skin secretion of Hylarana guentheri, is a peptide with modest antimicrobial activity. Several analogues were designed to explore the structure–activity relationship and enhance its activity. In general, the Rana box is not an indispensable motif for the bioactivity of Brevinin-2GUb, and the first to the 19th amino acids at the N-terminal end are active fragments, such that shortening the peptide while maintaining its bioactivity is a promising strategy for the optimisation of peptides. Keeping a complete hydrophobic face and increasing the net charges are key factors for antimicrobial activity. With the increase of cationic charges, α-helical proportion, and amphipathicity, the activity of t-Brevinin-2GUb-6K (tB2U-6K), in combatting bacteria, drastically improved, especially against Gram-negative bacteria, and the peptide attained the capacity to kill clinical isolates and fungi as well, which made it possible to address some aspects of antibiotic resistance. Thus, peptide tB2U-6K, with potent antimicrobial activity against antibiotic-resistant bacteria, the capacity to inhibit the growth of biofilm, and low toxicity against normal cells, is of value to be further developed into an antimicrobial agent

Entanglement distillation using particle statistics

We extend the idea of entanglement concentration for pure states(Phys. Rev. Lett. {\bf 88}, 187903) to the case of mixed states. The scheme works only with particle statistics and local operations, without the need of any other interactions. We show that the maximally entangled state can be distilled out when the initial state is pure, otherwise the entanglement of the final state is less than one. The distillation efficiency is a product of the diagonal elements of the initial state, it takes the maximum 50%, the same as the case for pure states.Comment: 3 pages, 1 figur

Brevinin-2GHk from Sylvirana guentheri and the design of truncated analogs exhibiting the enhancement of antimicrobial activity

Brevinins are an important antimicrobial peptide (AMP) family discovered in the skin secretions of Ranidae frogs. The members demonstrate a typical C-terminal ranabox, as well as a diverse range of other structural characteristics. In this study, we identified a novel brevinin-2 peptide from the skin secretion of Sylvirana guentheri, via cloning transcripts, and identifying the expressed mature peptide, in the skin secretion. The confirmed amino acid sequence of the mature peptide was designated brevinin-2GHk (BR2GK). Moreover, as a previous study had demonstrated that the N-terminus of brevinin-2 is responsible for exerting antimicrobial activity, we also designed a series of truncated derivatives of BR2GK. The results show that the truncated derivatives exhibit significantly improved antimicrobial activity and cytotoxicity compared to the parent peptide, except a Pro14 substituted analog. The circular dichroism (CD) analysis of this analog revealed that it did not fold into a helical conformation in the presence of either lipopolysaccharides (LPS) or TFE, indicating that position 14 is involved in the formation of the α-helix. Furthermore, three more analogs with the substitutions of Ala, Lys and Arg at the position 14, respectively, revealed the influence on the membrane disruption potency on bacteria and mammalian cells by the structural changes at this position. Overall, the N-terminal 25-mer truncates demonstrated the potent antimicrobial activity with low cytotoxicity