45,144 research outputs found
Can the Bump be Observed in the Early Afterglow of GRBS with X-Ray Line Emission Features?
Extremely powerful emission lines are observed in the X-ray afterglow of
several GRBs. The energy contained in the illuminating continuum which is
responsible for the line production exceeds 10 erg, much higher than
that of the collimated GRBs. It constrains the models which explain the
production of X-ray emission lines. In this paper, We argue that this energy
can come from a continuous postburst outflow. Focusing on a central engine of
highly magnetized millisecond pulsar or magnetar we find that afterglow can be
affected by the illuminating continuum, and therefore a distinct achromatic
bump may be observed in the early afterglow lightcurves. With the luminosity of
the continuous outflow which produces the line emission, we define the upper
limit of the time when the bump feature appears. We argue that the reason why
the achromatic bumps have not been detected so far is that the bumps should
appear at the time too early to be observed.Comment: 13 pags, 2 tables, appear in v603 n1 pt1 ApJ March 1, 2004 issu
Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases
Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei
gambiense and T. b. rhodesiense and caused devastating epidemics during the 20th
century. Due to effective control programs implemented in the last two decades, the
number of reported cases has fallen to a historically low level. Although fewer than
977 cases were reported in 2018 in endemic countries, HAT is still a public health
problem in endemic regions until it is completely eliminated. In addition, almost 150
confirmed HAT cases were reported in non-endemic countries in the last three
decades. The majority of non-endemic HAT cases were reported in Europe, United
States and South Africa, due to historical alliances, economic links or geographic
proximity to disease endemic countries. Furthermore, with the implementation of the
“Belt and Road” project, sporadic imported HAT cases have been reported in China
as a warning sign of tropical diseases prevention. In this paper, we explore and
interpret the data on HAT incidence and find no positive correlation between the
number of HAT cases from endemic and non-endemic countries.This data will
provide useful information for better understanding the imported cases of HAT
globally in the post-elimination phase
Dual-mode mechanical resonance of individual ZnO nanobelts
©2003 American Institute of Physics. The electronic version of this article is the complete one and can be found online at: http://link.aip.org/link/?APPLAB/82/4806/1DOI:10.1063/1.1587878The mechanical resonance of a single ZnO nanobelt, induced by an alternative electric field, was studied by in situ transmission electron microscopy. Due to the rectangular cross section of the nanobelt, two fundamental resonance modes have been observed corresponding to two orthogonal transverse vibration directions, showing the versatile applications of nanobelts as nanocantilevers and nanoresonators. The bending modulus of the ZnO nanobelts was measured to be ~52 GPa and the damping time constant of the resonance in a vacuum of 5×10–8 Torr was ~1.2 ms and quality factor Q = 500
Forward-backward asymmetry of photoemission in C excited by few-cycle laser pulses
We theoretically analyze angle-resolved photo-electron spectra (ARPES)
generated by the interaction of C with intense, short laser pulses. In
particular, we focus on the impact of the carrier-envelope phase (CEP) onto the
angular distribution. The electronic dynamics is described by time-dependent
density functional theory, and the ionic background of \csixty is
approximated by a particularly designed jellium model. Our results show a clear
dependence of the angular distributions onto the CEP for very short pulses
covering only very few laser cycles, which disappears for longer pulses. For
the specific laser parameters used in a recent experiments, a very good
agreement is obtained. Furthermore, the asymmetry is found to depend on the
energy of the emitted photoelectrons. The strong influence of the angular
asymmetry of electron emission onto the CEP and pulse duration suggests to use
this sensitivity as a means to analyze the structure of few-cycle laser pulses.Comment: 8 pages, 6 figure
A Simultaneous Quantum Secure Direct Communication Scheme between the Central Party and Other M Parties
We propose a simultaneous quantum secure direct communication scheme between
one party and other three parties via four-particle GHZ states and swapping
quantum entanglement. In the scheme, three spatially separated senders, Alice,
Bob and Charlie, transmit their secret messages to a remote receiver Diana by
performing a series local operations on their respective particles according to
the quadripartite stipulation. From Alice, Bob, Charlie and Diana's Bell
measurement results, Diana can infer the secret messages. If a perfect quantum
channel is used, the secret messages are faithfully transmitted from Alice, Bob
and Charlie to Diana via initially shared pairs of four-particle GHZ states
without revealing any information to a potential eavesdropper. As there is no
transmission of the qubits carrying the secret message in the public channel,
it is completely secure for the direct secret communication. This scheme can be
considered as a network of communication parties where each party wants to
communicate secretly with a central party or server.Comment: 4 pages, no figur
Generation of N-qubit W state with rf-SQUID qubits by adiabatic passage
A simple scheme is presented to generate n-qubit W state with
rf-superconducting quantum interference devices (rf-SQUIDs) in cavity QED
through adiabatic passage. Because of the achievable strong coupling for
rf-SQUID qubits embedded in cavity QED, we can get the desired state with high
success probability. Furthermore, the scheme is insensitive to position
inaccuracy of the rf-SQUIDs. The numerical simulation shows that, by using
present experimental techniques, we can achieve our scheme with very high
success probability, and the fidelity could be eventually unity with the help
of dissipation.Comment: to appear in Phys. Rev.
Modeling the functional genomics of autism using human neurons.
Human neural progenitors from a variety of sources present new opportunities to model aspects of human neuropsychiatric disease in vitro. Such in vitro models provide the advantages of a human genetic background combined with rapid and easy manipulation, making them highly useful adjuncts to animal models. Here, we examined whether a human neuronal culture system could be utilized to assess the transcriptional program involved in human neural differentiation and to model some of the molecular features of a neurodevelopmental disorder, such as autism. Primary normal human neuronal progenitors (NHNPs) were differentiated into a post-mitotic neuronal state through addition of specific growth factors and whole-genome gene expression was examined throughout a time course of neuronal differentiation. After 4 weeks of differentiation, a significant number of genes associated with autism spectrum disorders (ASDs) are either induced or repressed. This includes the ASD susceptibility gene neurexin 1, which showed a distinct pattern from neurexin 3 in vitro, and which we validated in vivo in fetal human brain. Using weighted gene co-expression network analysis, we visualized the network structure of transcriptional regulation, demonstrating via this unbiased analysis that a significant number of ASD candidate genes are coordinately regulated during the differentiation process. As NHNPs are genetically tractable and manipulable, they can be used to study both the effects of mutations in multiple ASD candidate genes on neuronal differentiation and gene expression in combination with the effects of potential therapeutic molecules. These data also provide a step towards better understanding of the signaling pathways disrupted in ASD
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