11,661 research outputs found
Guest Editorial Special Issue on Graph-Powered Machine Learning for Internet of Things
Internet of Things (IoT) refers to an ecosystem where applications and services are driven by data collected from devices interacting with each other and the physical world. Although IoT has already brought spectacular benefits to human society, the progress is actually not as fast as expected. From network structures to control flow graphs, IoT naturally generates an unprecedented volume of graph data continuously, which stimulates fertilization and making use of advanced graph-powered methods on the diverse, dynamic, and large-scale graph IoT data
Bounce and cyclic cosmology in extended nonlinear massive gravity
We investigate non-singular bounce and cyclic cosmological evolutions in a
universe governed by the extended nonlinear massive gravity, in which the
graviton mass is promoted to a scalar-field potential. The extra freedom of the
theory can lead to certain energy conditions violations and drive cyclicity
with two different mechanisms: either with a suitably chosen scalar-field
potential under a given Stuckelberg-scalar function, or with a suitably chosen
Stuckelberg-scalar function under a given scalar-field potential. Our analysis
shows that extended nonlinear massive gravity can alter significantly the
evolution of the universe at both early and late times.Comment: 20 pages, 5 figures, version published at JCA
Novel Scaling Behavior for the Multiplicity Distribution under Second-Order Quark-Hadron Phase Transition
Deviation of the multiplicity distribution in small bin from its
Poisson counterpart is studied within the Ginzburg-Landau description for
second-order quark-hadron phase transition. Dynamical factor for the distribution and ratio are defined, and
novel scaling behaviors between are found which can be used to detect the
formation of quark-gluon plasma. The study of and is also very
interesting for other multiparticle production processes without phase
transition.Comment: 4 pages in revtex, 5 figures in eps format, will be appeared in Phys.
Rev.
Radio Observations of Star Forming Galaxies in the SKA era
We have combined determinations of the epoch-dependent star formation rate (SFR) function with relationships between SFR and radio (synchrotron and free-free) emission to work out detailed predictions for the counts and the redshift distributions of star-forming galaxies detected by planned Square Kilometer Array (SKA) surveys. The evolving SFR function comes from recent models fitting the far-infrared (FIR) to millimeter-wave luminosity functions and the ultraviolet (UV) luminosity functions up to z=10, extended to take into account additional UV survey data. We used very deep 1.4 GHz number counts from the literature to check the relationship between SFR and synchrotron emission, and the 95 GHz South Pole Telescope (SPT) counts of dusty galaxies to test the relationship between SFR and free-free emission. We show that the SKA will allow us to investigate the SFRs of galaxies down to few Msun/yr up to z=10, thus extending by more than two orders of magnitude the high-z SFR functions derived from Herschel surveys. SKA1-MID surveys, down to microJy levels, will detect hundreds of strongly lensed galaxies per square degree; a substantial fraction of them will show at least two images above the detection limits
Phenomenological Scaling of Rapidity Dependence for Anisotropic Flows in 25 MeV/nucleon Ca + Ca by Quantum Molecular Dynamics Model
Anisotropic flows (, , and ) of light fragments up till
the mass number 4 as a function of rapidity have been studied for 25
MeV/nucleon Ca + Ca at large impact parameters by Quantum
Molecular Dynamics model. A phenomenological scaling behavior of rapidity
dependent flow parameters (n = 1, 2, 3 and 4) has been found as a
function of mass number plus a constant term, which may arise from the
interplay of collective and random motions. In addition, keeps
almost independent of rapidity and remains a rough constant of 1/2 for all
light fragments.Comment: 4 pages, 5 figure
A Lorentz Invariance Violating Cosmology on the DGP Brane
We study cosmological implications of a Lorentz invariance violating
DGP-inspired braneworld scenario. A minimally coupled scalar field and a
single, fixed-norm, Lorentz-violating timelike vector field within an
interactive picture provide a wide parameter space which accounts for late-time
acceleration and transition to phantom phase of the scalar field.Comment: 23 pages, 8 figures, accepted for publication in JCA
Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen
Aberrant activation of the androgen receptor (AR) may play a critical role in castration resistant prostate cancer. After ligand binding, AR is recruited to the androgen responsive element (ARE) sequences on the DNA where AR interaction with coactivators and corepressors modulates transcription. We demonstrated that phosphorylation of AR at Tyr-267 by Ack1/TNK2 tyrosine kinase results in nuclear translocation, DNA binding, and androgen-dependent gene transcription in a low androgen environment. In order to dissect downstream mechanisms, we searched for proteins whose interaction with AR was regulated by Ack1. SLIRP (SRA stem-loop interacting RNA binding protein) was identified as a candidate protein. Interaction between AR and SLIRP was disrupted by Ack1 kinase activity as well as androgen or heregulin treatment. The noncoding RNA, SRA, was required for AR-SLIRP interaction. SLIRP was bound to ARE’s of AR target genes in the absence of androgen. Treatment with androgen or heregulin led to dissociation of SLIRP from the ARE. Whole transcriptome analysis of SLIRP knockdown in androgen responsive LNCaP cells showed that SLIRP affects a significant subset of androgen-regulated genes. Our data suggest that Ack1 kinase and androgen regulate interaction between AR and SLIRP and that SLIRP functions as a coregulator of AR with properties of a corepressor in a context-dependent manner
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