560 research outputs found
Phase coherent transport in SrTiO3/LaAlO3 interfaces
The two dimensional electron gas formed between the two band insulators
SrTiO3 and LaAlO3 exhibits a variety of interesting physical properties which
make it an appealing material for use in future spintronics and/or quantum
computing devices. For this kind of applications electrons have to retain their
phase memory for sufficiently long times or length. Using a mesoscopic size
device we were able to extract the phase coherence length, and its temperature
variation. We find the dephasing rate to have a power law dependence on
temperature. The power depends on the temperature range studied and sheet
resistance as expected from dephasing due to strong electron-electron
interactions.Comment: Submitted to Phys. Rev
Ataxia-telangiectasia: Linkage analysis in highly inbred Arab and Druze families and differentiation from an ataxia-microcephaly-cataract syndrome
Ataxia-telangiectasia (A-T) is a progressive autosomal recessive disease featuring neurodegeneration, immunodeficiency, chromosomal instability, radiation sensitivity and a highly increased proneness to cancer. A-T is ethnically widespread and genetically heterogeneous, as indicated by the existence of four complementation groups in this disease. Several "A-T-like" genetic diseases share various clinical and cellular characteristics with A-T. By using linkage analysis to study North American and Turkish A-O families, the ATA (A-T, complementation group A) gene has been mapped to chromosome 11q23. A number of Israeli Arab A-T patients coming from large, highly inbred families were assigned to group A In one of these families, an additional autosomal recessive disease was identified, characterized by ataxia, hypotonia, microcephaly and bilateral congenital cataracts. In two patients with this syndrome, normal levels of serum immunoglobulins and alpha-fetoprotein, chromosomal stability in peripheral blood lymphocytes and skin fibroblasts, and normal cellular response to treatments with X-rays and the radiomimetic drug neocarzinostatin indicated that this disease does not share, with A-T, any additional features other than ataxia. These tests also showed that another patient in this family, who is also mentally retarded, is affected with both disorders. This conclusion was further supported by linkage analysis with 11q23 markers. Lod scores between A-O and these markers, cumulated over three large Arab families, were significant and confirmed the localization of the ATA gene to aq23. However, another Druze family unassigned to a specific complementation group, showed several recombinants between A-T and the same markers, leaving the localization of the A-T gene in this family open
A specific RAD51 haplotype increases breast cancer risk in Jewish non-Ashkenazi high-risk women
While the precise genes involved in determining familial breast cancer risk in addition to BRCA1/2 are mostly unknown, one strong candidate is RAD51. Jewish non-Ashkenazi women at high-risk for breast/ovarian cancer and ethnically matched controls were genotyped using four single nucleotide polymorphisms spanning the RAD51 genomic region, and the resulting haplotypes were constructed using the GERBIL algorithm. A total of 314 individuals were genotyped: 184 non-Ashkenazi high-risk women (119 with breast cancer), and 130 unaffected, average-risk ethnically matched controls. Using GEBRIL, three frequent haplotypes were constructed. One of the haplotypes (TGTA -coined haplotype 3) was present in 7.3% (19/260 haplotypes) of controls (n = 130) and in 16.8% (40/238 haplotypes) of high-risk breast cancer patients (n = 119, P = 0.001). A specific RAD51 haplotype is more prevalent among non-Ashkenazi Jewish high-risk women than in average-risk population
Spin-Polarized Transport Across an LaSrMnO/YBaCuO Interface: Role of Andreev Bound States
Transport across an
LaSr_{3}/YBa_{3}_{7}_{3}$/YBCO and Ag/YBCO. In all cases, YBCO is used as bottom layer to
eliminate the channel resistance and to minimize thermal effects. The observed
differential conductance re ects the role of Andreev bound states in a-b
planes, and brings out for the first time the suppression of such states by the
spin-polarized transport across the interface. The theoretical analysis of the
measured data reveals decay of the spin polarization near the LSMO surface with
temperature, consistent with the reported photoemission data.Comment: 5 pages LaTeX, 3 eps figures included, accepted by Physical Review
Localization by disorder in the infrared conductivity of (Y,Pr)Ba2Cu3O7 films
The ab-plane reflectivity of (Y{1-x}Prx)Ba2Cu3O7 thin films was measured in
the 30-30000 cm-1 range for samples with x = 0 (Tc = 90 K), x = 0.4 (Tc = 35 K)
and x = 0.5 (Tc = 19 K) as a function of temperature in the normal state. The
effective charge density obtained from the integrated spectral weight decreases
with increasing x. The variation is consistent with the higher dc resistivity
for x = 0.4, but is one order of magnitude smaller than what would be expected
for x = 0.5. In the latter sample, the conductivity is dominated at all
temperatures by a large localization peak. Its magnitude increases as the
temperature decreases. We relate this peak to the dc resistivity enhancement. A
simple localization-by-disorder model accounts for the optical conductivity of
the x = 0.5 sample.Comment: 7 pages with (4) figures include
Observation of Andreev reflection in the c-axis transport of Bi_2Sr_2CaCu_2O_{8+x} single crystals near T_c and search for the preformed-pair state
We observed an enhancement of the -axis differential conductance around
the zero-bias in AuBiSrCaCuO (Bi2212) junctions near the
superconducting transition temperature . We attribute the conductance
enhancement to the Andreev reflection between the surface Cu-O bilayer with
suppressed superconductivity and the neighboring superconducting inner bilayer.
The continuous evolution from depression to an enhancement of the zero-bias
differential conductance, as the temperature approaches from below,
points to weakening of the barrier strength of the non-superconducting layer
between adjacent Cu-O bilayers. We observed that the conductance enhancement
persisted up to a few degrees above in junctions prepared on slightly
overdoped Bi2212 crystals. However, no conductance enhancement was observed
above in underdoped crystals, although recently proposed theoretical
consideration suggests an even wider temperature range of enhanced zero-bias
conductance. This seems to provide negative perspective to the existence of the
phase-incoherent preformed pairs in the pseudogap state.Comment: 17 pages including 4 figure
Sentence entailment in compositional distributional semantics
Distributional semantic models provide vector representations for words by
gathering co-occurrence frequencies from corpora of text. Compositional
distributional models extend these from words to phrases and sentences. In
categorical compositional distributional semantics, phrase and sentence
representations are functions of their grammatical structure and
representations of the words therein. In this setting, grammatical structures
are formalised by morphisms of a compact closed category and meanings of words
are formalised by objects of the same category. These can be instantiated in
the form of vectors or density matrices. This paper concerns the applications
of this model to phrase and sentence level entailment. We argue that
entropy-based distances of vectors and density matrices provide a good
candidate to measure word-level entailment, show the advantage of density
matrices over vectors for word level entailments, and prove that these
distances extend compositionally from words to phrases and sentences. We
exemplify our theoretical constructions on real data and a toy entailment
dataset and provide preliminary experimental evidence.Comment: 8 pages, 1 figure, 2 tables, short version presented in the
International Symposium on Artificial Intelligence and Mathematics (ISAIM),
201
Sex differences in prehospital delays in patients with st-segment-elevation myocardial infarction undergoing percutaneous coronary intervention
BACKGROUND: Women with ST-segment-elevation myocardial infarction experience delays in reperfusion compared with men with little data on each time component from symptom onset to reperfusion. This study analyzed sex discrepancies in patient delays, prehospital system delays, and hospital delays. METHODS AND RESULTS: Consecutive patients with ST-segment-elevation myocardial infarction treated with percutaneous coronary intervention across 30 hospitals in the Victorian Cardiac Outcomes Registry (2013-2018) were analyzed. Data from the Ambulance Victoria Data warehouse were used to perform linkage to the Victorian Cardiac Outcomes Registry for all patients transported via emergency medical services (EMS). The primary end point was EMS call-to-door time (prehospital system delay). Secondary end points included symptom-to-EMS call time (patient delay), door-to-device time (hospital delay), 30-day mortality, major adverse cardiovascular events, and major bleeding. End points were analyzed according to sex and adjusted for age, comorbidities, cardiogenic shock, cardiac arrest, and symptom onset time. A total of 6330 (21% women) patients with ST-segment-elevation myocardial infarction were transported by EMS. Compared with men, women had longer adjusted geometric mean symptom-to-EMS call times (47.0 versus 44.0 minutes; P<0.001), EMS call-to-door times (58.1 versus 55.7 minutes; P<0.001), and door-to-device times (58.5 versus 54.9 minutes; P=0.006). Compared with men, women had higher 30-day mortality (odds ratio [OR], 1.38; 95% CI, 1.06-1.79; P=0.02) and major bleeding (OR, 1.54; 95% CI, 1.08-2.20; P=0.02). CONCLUSIONS: Female patients with ST-segment-elevation myocardial infarction experienced excess delays in patient delays, prehospital system delays, and hospital delays, even after adjustment for confounders. Prehospital system and hospital delays resulted in an adjusted excess delay of 10 minutes compared with men
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