10 research outputs found
Smoking related cancers and loci at chromosomes 15q25, 5p15, 6p22.1 and 6p21.33 in the Polish population
- Author
- Cybulski Cezary
- Grodzki Tomasz
- Jakubowska Anna
- Jaworowska Ewa
- Lener Marcin R.
- Lubiński Jakub
- Lubiński Jan
- Masojć Bartłomiej
- McKay James D.
- Nej-Wołosiak Katarzyna
- Oszutowska Dorota
- Renard Hélène
- Scott Rodney J.
- Serwatowski Piotr
- Sikorski Andrzej
- Słojewski Marcin
- Tołoczko-Grabarek Aleksandra
- Trubicka Joanna
- Wokołorczyk Dominika
- Złowocka-Perłowska Elżbieta
- Publication venue
- Public Library Of Science
- Publication date
- 01/01/2011
- Field of study
Genetic factors associated with the risk of smoking related cancers have until recently remained elusive. Since the publication of a genome-wide association study (GWAS) on lung cancer new genetic loci have been identified that appear to be associated with disease risk. In this replication study we genotyped 14 single nucleotide polymorphisms (SNPs) located at the 5p12.3-p15.33, 6p21.3-p22.1, 6q23-q27 and 15q25.1 loci in 874 lung, 450 bladder, 418 laryngeal cancer cases and cancer-free controls, matched by year of birth and sex to the cases. Our results revealed that loci in the chromosome region 15q25.1 (rs16969968[A], rs8034191[G]) and 5p15 (rs402710[T]) are associated with lung cancer risk in the Polish population (smoking status adjusted OR = 1.45, 1.35, 0.77; p≤0.0001, 0.0005, 0.002; 95%CI 1.23–1.72, 1.14–1.59, 0.66–0.91 respectively). None of the other regions analyzed herein were implicated in the risk of lung, bladder or laryngeal cancer. This study supports previous findings on lung cancer but fails to show association of SNPs located in 15q25.1 and 5p15 region with other smoking related cancers like bladder and laryngeal cancer
Selenium as marker for cancer risk and prevention
- Author
- Ashuryk Olgierd
- Byrski Tomasz
- Cybulski Cezary
- Durda Katarzyna
- Dębniak Tadeusz
- Grodzki Tomasz
- Gronwald Jacek
- Gupta Satish
- Górecka-Szyld Barbara
- Huzarski Tomasz
- Jakubowska Anna
- Jaworowska Ewa
- Jaworska Katarzyna
- Kładny Józef
- Lener Marcin
- Lubiński Jakub
- Lubiński Jan
- Morawski Antoni
- Muszyńska Magdalena
- Sukiennicki Grzegorz
- Sulikowski Mieczysław
- Tołoczko-Grabarek Aleksandra
- Wiechowska-Kozłowska Anna
- Wilk Grażyna
- Złowocka-Perłowska Elżbieta
- Publication venue
- 'Index Copernicus'
- Publication date
- 01/10/2012
- Field of study
Smoking Related Cancers and Loci at Chromosomes 15q25, 5p15, 6p22.1 and 6p21.33 in the Polish Population
- Author
- A Matakidou
- Aleksandra Tołoczko-Grabarek
- AM Krais
- Amanda Ewart Toland
- Andrzej Sikorski
- Anna Jakubowska
- Bartłomiej Masojć
- Cezary Cybulski
- CI Amos
- CK Garcia
- D Chen
- Dominika Wokołorczyk
- Dorota Oszutowska
- EH Lips
- Elżbieta Złowocka-Perłowska
- Ewa Jaworowska
- G Jin
- H Furberg
- Hélène Renard
- I Menashe
- J Ferlay
- Jakub Lubiński
- James D. McKay
- Jan Lubiński
- JC Barrett
- JC Wang
- JD McKay
- JD Minna
- Joanna Trubicka
- K Shiraishi
- K Yamamoto
- Katarzyna Nej-Wołosiak
- LJ Bierut
- M Armanios
- M Gago-Dominguez
- M You
- M Zoli
- Marcin R. Lener
- Marcin Słojewski
- MR Spitz
- MT Landi
- N Caporaso
- NL Saccone
- NL Saccone
- P Liu
- P Liu
- Piotr Serwatowski
- RJ Hung
- Rodney J. Scott
- RP Young
- S Fang
- SA Miller
- SA Savage
- SG Pillai
- ST Sherry
- T Rafnar
- T Truong
- TE Thorgeirsson
- Tomasz Grodzki
- Y Wang
- Y Wang
- Y Wang
- Y Wang
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Identification of six new susceptibility loci for invasive epithelial ovarian cancer.
- Author
- Aalfs C M
- Aalfs Cora M
- Aben Katja K H
- Adenis Claude
- Adlard Julian
- Agata Simona
- Aghajanian Carol A
- Aghmesheh Morteza
- Agnarsson Bjarni A
- Aittomäki Kristiina
- Akloul Linda
- Alducci Elisa
- Allavena Anna
- Amor David
- Andersen Mette K
- Andrews Lesley
- Andrulis Irene L
- Antill Yoland
- Anton-Culver Hoda
- Antonenkova Natalia
- Antoniou Antonis C
- Apostolou Paraskevi
- Arason Adalgeir
- Ardern-Jones Audrey
- Ardnor Christina Edwinsdotter
- Aretini Paolo
- Armitage Shane
- Arnold Leanne
- Arnold Norbert
- Arun Banu K
- Arver Brita
- Attard Virginia
- Ausems M G E M
- Ausems Margreet G E M
- Azmi Mat Adenan Noor
- Azodi Masoud
- Bae-Jump Victoria L
- Baker Helen
- Balleine Rosemary
- Balmana Judith
- Bancroft Elizabeth
- Bandera Elisa V
- Bankier Agnes
- Bardsley Cathryn
- Barile Monica
- Barjhoux Laure
- Barkardottir Rosa B
- Barouk-Simonet Emmanuelle
- Barrowdale Daniel
- Barton David
- Barwell Julian
- Basil Jack B
- Bastick Patti
- Baumgärtner Anne
- Bean Yukie
- Becker Alexandra
- Beckmann Matthias W
- Beesley Jonathan
- Beilby John
- Belotti Muriel
- Benitez Javier
- Bennett Barbara
- Bennett Ian
- Berchuck Andrew
- Berger Andreas
- Berger Raanan
- Berlin Cheryl
- Bernard Loris
- Berry Geoffrey
- Berthet Pascaline
- Bignon Yves-Jean
- Birot Anne-Marie
- Bisogna Maria
- Bjorge Line
- Blackburn Anneke
- Blanco Ignacio
- Blank Stephanie V
- Blok M J
- Blok Marinus J
- Blom Marie-Jose
- bniak Tadeusz D
- Bogdanova Natalia
- Boggess John F
- Bogwitz Michael
- Bojesen Anders
- Bonadona Valérie
- Bonanni Bernardo
- Bonnet Françoise
- Borg Ake
- Bosch Nina
- Bourdon Violaine
- Boutry-Kryza Nadia
- Bove Betsy
- Bowtell D
- Bradshaw Nicola
- Brennan Meagan
- Bressac-de Paillerets Brigitte
- Bressac-de-Paillerets Brigitte
- Brewer Carole
- Brice Glen
- Brinton Louise A
- Bronner Myriam
- Brooks-Wilson Angela
- Brown Melissa
- Bruinsma Fiona
- Brunet Joan
- Bubien Virginie
- Buckley Michael
- Buecher Bruno
- Burgess Matthew
- Burke Jo
- Bustinza Gisela Barbany
- Butow Phyllis
- Butzow Ralf
- Buys Saundra S
- Byron John W
- Byron Keith
- Byrski Tomasz
- Caldes Trinidad
- Calender Alain
- Caligo Maria A
- Callen David
- Campbell Ian
- Capella Gabriel
- Capra Fabio
- Caron Olivier
- Carter Jonathan
- Carty Karen
- Casella Cinzia
- Castera Laurent
- Cattaneo Elisa
- Catts Zohra Ali-Kahn
- Caux-Moncoutier Virginie
- Chan Salina B
- Chan T L
- Chang-Claude Jenny
- Chauhan Deepa
- Chauhan Manisha
- Chen Ann
- Chen Xiaoqing
- Chen Zhihua
- Chenevix-Trench G
- Chiquette Jocelyne
- Christian Alice
- Chu Carol
- Chung Wendy K
- Claber Oonagh
- Claes Kathleen
- Clarke Christine
- Coetzee Gerry
- Coetzee Simon
- Cohn David E
- Colas Chrystelle
- Cole Trevor
- Collavoli Anita
- Collee J Margriet
- Collet Agnès
- Colley Alison
- Collier Rebecca
- Collonge-Rame Marie-Agnès
- Collée J M
- Concannon Patrick
- Cook Jackie
- Cook Linda S
- Cook Margaret
- Corines Marina
- Coron Fanny
- Cotton Dick
- Couch Fergus J
- Coulet Florence
- Coupier Isabelle
- Cramer Daniel W
- Crawford Gillian
- Crook Ashley
- Cui James
- Culling Bronwyn
- Cummings Margaret
- Cunningham Julie
- Cybulski Cezary
- D'Andrea Emma
- Dall'Olio Valentina
- Daly Mary B
- Damiola Francesca
- Dansonka-Mieszkowska Agnieszka
- Darder Esther
- Davidson Rosemarie
- Dawson Sarah-Jane
- de Bock G H
- de la Hoya Miguel
- de Lange J L
- De Leeneer Kim
- De Paepe Anne
- de Pauw Antoine
- deFazio A
- deFazio Anna
- Deissler Helmut
- Del Valle Jesus
- Delatycki Martin
- Delnatte Capucine
- DeMars Leslie R
- Dennis Joe
- Devilee P
- Devilee Peter
- Dicks Ed
- Dickson Rebecca
- Diez Orland
- Ding Yuan Chun
- DiSilvestro Paul A
- Ditsch Nina
- Dixon Joanne
- Dobrovic Alexander
- Doherty Jennifer A
- Dolcetti Riccardo
- Domchek Susan M
- Donaldson Alan
- Dorfling Cecilia M
- Dorkins Huw
- Douglas Fiona
- Downing Sarah
- Dreyfus Hélène
- Drummond Sarah
- du Bois Andreas
- Dudding Tracy
- Dumont Martine
- Duncan Alexis
- Dunning Alison M
- Duran Mercedes
- Durda Katarzyna
- Durell Sarah
- Dutra-Clarke Anna
- Dörk Thilo
- Dürst Matthias
- Eason Jacqueline
- Easton Douglas F
- Eccles Diana
- Eddy Charlotte
- Edkins Ted
- Edwards Robert P
- Edwards Stacey
- Eeles Ros
- Eglitis Janis
- Ehrencrona Hans
- Eilber Ursula
- Einbeigi Zakaria
- Eisenbruch Maurice
- Eisinger François
- Ejlertsen Bent
- Ekici Arif B
- Elan Camille
- Ellis Ian
- Ellis Steve
- Emanuelsson Monica
- Engel Christoph
- Engert Stefanie
- Evans D Gareth
- Faivre Laurence
- Farshid Gelareh
- Fasching Peter A
- Fassy-Colcombet Marion
- Fawcett Susan
- Feillel Viviane
- Feliubadalo Lidia
- Fellows Andrew
- Fenton Georgina
- Feroce Irene
- Ferrer Sandra Fert
- Ficarazzi Filomena
- Field Michael
- Fineberg Elena
- Fink-Retter Anneliese
- Fiorica James V
- Firgaira Frank
- Flanagan James
- Fleming Jean
- Fong Peter
- Fontaine Annette
- Foo Claire
- Forbes John
- Foretova Lenka
- Fortuzzi Stefano
- Fostira Florentia
- Foulkes William D
- Fountzilas George
- Fourme Emmanuelle
- Fournier Jean-Philippe Peyrat Joëlle
- Fournier Joëlle
- Fox Stephen
- Fredericksen Zachary
- Freedman Matt
- Frenay Marc
- French Juliet
- Fricker Jean-Pierre
- Fridley Brooke L
- Friebel Tara
- Friedlander Michael
- Friedman Eitan
- Frost Debra
- Frénay Marc
- Gadzicki Dorothea
- Gaff Clara
- Ganschow Pamela
- Ganz Patricia A
- Gao Yu-Tang
- Garber Judy
- Garcia Encarna B Gómez
- Garcia Maria Jose
- Gardner Mac
- Gattas Mike
- Gaudet Mia M
- Gauthier-Villars Marion
- Gayther Simon
- Gayther Simon A
- Gehrig Andrea
- Gentry-Maharaj Aleksandra
- Genuardi Maurizio
- George Angela
- George Peter
- Gerdes Anne-Marie
- Gertig D
- Gibson Sarah
- Giles Graham
- Gill Grantley
- Gille J J P
- Giraud Sophie
- Gismondi Viviana
- Gladieff Laurence
- Glasspool Rosalind
- Glendon Gord
- Godino Javier
- Godwin Andrew K
- Goff Sheila
- Goldblatt Jack
- Goldgar David E
- Golmard Lisa
- Goode Ellen L
- Goodman Marc T
- Goodman Selina
- Gorski Bohdan
- Green Adele C
- Greene Mark H
- Greening Sian
- Gregory Helen
- Grist Scott
- Gronwald Jacek
- Guillaud-Bataille Marine
- Guimbaud Rosine
- Gómez-Garcia E B
- Haan Eric
- Hahnen Erick
- Hall Per
- Halliday Dorothy
- Hamann Ute
- Handallou Sandrine
- Hansen Thomas V O
- Haque Eshika
- Harbst Katja
- Hardie Kate
- Hardouin Agnès
- Harrington Patricia
- Harris Marion
- Hart Steven
- Hart Stewart
- Harter Philipp
- Hasmad Hanis Nazihah
- Hayward Nicholas K
- Hayward Nick
- Hazelett Dennis
- Healey Sue
- Heidemann Simone
- Hein Alexander
- Heiniger Louise
- Heinritz Wolfram
- Heitz Florian
- Henderson Alex
- Henriksson Karin
- Herzog Josef
- Hildebrandt Michelle A T
- Hill Kathryn
- Hillemanns Peter
- Hodgson Shirley
- Hoffman James S
- Hoffman Jonathan
- Hogdall Claus
- Hogdall Estrid
- Hogervorst F B L
- Hogervorst Frans B L
- Holland Helene
- Hollestelle Antoinette
- Hoogerbrugge Nicoline
- Hooning M J
- Hooning Maartje J
- Hopper John
- Hosono Satoyo
- Houdayer Claude
- Houghton Catherine
- Hulick Peter
- Humphrey Evelyn
- Hunt Clare
- Huo Dezheng
- Hurteau Jean A
- Huzarski Tomasz
- ichert Gabriella
- Iglesias Silvia
- Imyanitov Evgeny N
- Isaacs Claudine
- Isaccs Claudine
- Iversen Edwin S
- Izatt Louise
- Izquierdo Angel
- Jacobs Chris
- Jager Agnes
- Jakubowska Anna
- James Margaret
- James Paul
- Janavicius Ramunas
- Jaworska-Bieniek Katarzyna
- Jeffers Lisa
- Jenkins Mark
- Jensen Allan
- Jensen Uffe Birk
- Jernström Helena
- Ji Bu-Tian
- Jobson Irene
- Johannsson Oskar Th
- John Esther M
- Jones Alison
- Jønson Lars
- Karlan Beth Y
- Karlsson Per
- Kast Karin
- Kauff Noah
- Kaufman Bella
- Kaulich Daphne Geschwantler
- Kefford Rick
- Kelemen Linda E
- Kellar Melissa
- Kelley Joseph L
- Kemp Zoe
- Kennedy M John
- Kets C M
- Kets Carolien M
- Khan Sofia
- Kidd Alexa
- Kiely Belinda
- Kiemeney Lambertus A
- Kientz Caroline
- Kim Sung-Won
- Kirchhoff Tomas
- Kirk Judy
- Kivuva Emma
- Kjaer Susanne Kruger
- Kleibl Zdenek
- Kluijt Irma
- Knol-Bout Jacoba P
- Koehler Jessica
- Kohut Kelly
- Kollias James
- Komenaka Ian
- Konstantopoulou Irene
- Kosel Matthew
- Kovalenko Serguei
- Krakstad Camilla
- Kriege Mieke
- Kristoffersson Ulf
- Kruse Torben A
- Kuchenbaecker Karoline B
- Kupryjanczyk Jolanta
- Kwong Ava
- Laframboise Rachel
- Laitman Yael
- Lakhani Sunil
- Lalloo Fiona
- Lambo Rosanna
- Lambrechts Diether
- Lambrechts Sandrina
- Langman Caroline
- Lasa Adriana
- Lasset Christine
- Lawrenson Kate
- Lazaro Conxi
- Le Nhu D
- Leaming Amanda
- Leary Jennifer
- Lebrun Marine
- Lee Adam
- Lee Alice W
- Lee Andrew
- Lee Annette
- Lee Janet M
- Lee Jong Won
- Lee Min Hyuk
- Lefol Cédrick
- Lejbkowicz Flavio
- Lele Shashi
- Leminen Arto
- Leroux Dominique
- Lesperance Bernard
- Lester Jenny
- Lesueur Fabienne
- Levine Douglas A
- Li Qiyuan
- Liang Dong
- Liedgren Sigrun
- Ligtenberg Marjolijn J L
- Liljegren Annelie
- Lim Jacqueline
- Lin Hui-Yi
- Lin Yvonne G
- Lindblom Annika
- Lindeman Geoff
- Lindor Noralane
- Lipton Lara
- Lissowska Jolanta
- Lobb Liz
- Loman Niklas
- Longmuir Mark
- Longy Michel
- Loud Jennifer T
- Lu Karen H
- Lubinski Jan
- Lucassen Anneke
- Lundvall Lene
- Lynch Henry T
- Léone Mélanie
- Léoné Mélanie
- Ma Edmund
- Machackova Eva
- Mai Phuong L
- Male Alison
- Mann Graham
- Manoukian Siranoush
- Mariani Paolo
- Mariette Frederique
- Marsh Deborah
- Martayan Aline
- Massuger Leon F A G
- Matsuo Keitaro
- Maugard Christine
- Mazoyer Sylvie
- McBride Donna
- McCann Emma
- McGuffog Lesley
- McGuire Valerie
- McLachlan Sue Anne
- McLaughlin John R
- McLeod Diane
- McNeish Ian
- Meijers-Heijboer H E J
- Meijers-Heijboer Hanne E J
- Meindl Alfons
- Meiser Bettina
- Meldrum Cliff
- Melin Beatrice
- Melloni Giulia
- Menendez Mireia
- Menkiszak Janusz
- Menon Usha
- Mensenkamp A R
- Mensenkamp Arjen R
- Miedzybrodzka Zosia
- Milne Roger
- Miron Alex
- Mitchell Gillian
- Modugno Francesmary
- Moeller Sanne Traasdahl
- Moncoutier Virginie
- Montagna Marco
- Monteiro Alvaro N
- Morrison Patrick
- Morrison Patrick J
- Mortemousque Isabelle
- Mourits M J
- Moysich Kirsten B
- Muller Danièle
- Mulligan Anna Marie
- Muranen Taru A
- Murday Victoria
- Murray Alex
- Murray Alexandra
- Narod Steven A
- Nathanson Katherine L
- Navarro Matilde
- Nedergaard Lotte
- Nerenstone Stacy R
- Ness Roberta B
- Neuhausen Susan L
- Nevanlinna Heli
- Newman Beth
- Niederacher Dieter
- Niedermayr Eveline
- Nielsen Finn C
- Nielsen Sarah
- Nightingale Sophie
- Nikitina-Zake Liene
- Noguchi Tetsuro
- Nogues Catherine
- Nordling Margareta
- Noushmehr Houtan
- Nussbaum Robert L
- O'Connell Shona
- O'Loughlin Imelda
- O'Malley David M
- Obdeijn I M
- Odunsi Kunle
- Offit Kenneth
- Olah Edith
- Oliver Clare
- Olopade Olufunmilayo I
- Olson Sara H
- Olsson Håkan
- Olswold Curtis
- Ong Kai-ren
- Oosterwijk J C
- Oosterwijk Jan C
- Orlow Irene
- Orsulic Sandra
- Osborne Richard
- Osorio Ana
- Ottini Laura
- Overbeek L I H
- Ozcelik Hilmi
- Pachter Nick
- Page Elizabeth
- Pankratz Vernon S
- Papi Laura
- Papp Janos
- Park Sue K
- Parsons Peter G
- Pasini Barbara
- Paterson Joan
- Patrick-Miller Linda
- Patterson Briony
- Paul James
- Pearce Celeste L
- Pedersen Inge Sokilde
- Peissel Bernard
- Peixoto Ana
- Pejovic Tanja
- Pelttari Liisa M
- Pensotti Valeria
- Peock Susan
- Perkins Jo
- Permuth-Wey Jenny
- Peterlongo Paolo
- Peters Lester
- Peyrat Jean-Philippe
- Peysselon Magalie
- Pfeiler Georg
- Pharoah Paul D P
- Pharoah Paul P
- Phelan Catherine M
- Phillips Kelly
- Piedmonte Marion
- Pigg Maritta Hellström
- Pike Malcolm C
- Pilato Brunella
- Plante Marie
- Platte Radka
- Plendl Hansjoerg
- Pocza Timea
- Pohlreich Petr
- Poole Elizabeth M
- Pope Jenny
- Poppe Bruce
- Porteous Mary
- Porteous Mary E
- Preisler-Adams Sabine
- Price Melanie
- Prieur Fabienne
- Przybylo Jennifer
- Pujana Miquel Angel
- Pujol Pascal
- Purdie David M
- Purser Lynne
- Putignano Anna Laura
- Quarrell Oliver
- Radice Paolo
- Rahman Nazneen
- Ramus Susan J
- Rantala Johanna
- Rappaport Christine
- Rashid Muhammad Usman
- Rebbeck Timothy R
- Rebischung Christine
- Reeve Jeanne
- Reeve Tony
- Remenieras Audrey
- Remon Marie-Alice
- Rennert Gad
- Rhiem Kerstin
- Richards Robert
- Rickard Edwina
- Risch Harvey A
- Robinson Bridget
- Robson Mark
- Rodriguez Gustavo C
- Rogers Mark T
- Romero Atocha
- Rookus M A
- Rookus Matti A
- Rosen Barry
- Rosenquist Richard
- Rossing Mary Anne
- Rothstein Joseph H
- Rouleau Etienne
- Roversi Gaia
- Rudaitis Vilius
- Rudolph Anja
- Rudzki Barney
- Rudzki Bridget Robinson Barney
- Ruehl Ina
- Runnebaum Ingo B
- Russell N S
- Rzepecka Iwona K
- Révillion Françoise
- Salani Ritu
- Saleh Mona
- Salinas Monica
- Salisbury Elizabeth
- Salvesen Helga B
- Sambrook Joe
- Sardella Domenico
- Sarrel Kara
- Saunders Christobel
- Saunus Jodi
- Savage Sharon A
- Savarese Antonella
- Saya Sibel
- Sayer Robyn
- Schildkraut Joellen M
- Schmidt M K
- Schmutzler Rita Katharina
- Schrijver Lieske H
- Schwaab Ira
- Schwartz Peter E
- Schäfer Dieter
- Scott Clare
- Scott Elizabeth
- Scott Rodney
- Scuvera Giulietta
- Searle Anne
- Segura Pedro Perez
- Seldon Joyce
- Selkirk Christina
- Sellers Thomas A
- Senter Leigha
- Serra-Feliu Gemma
- Seshadri Ram
- Sevenet Nicolas
- Sexton Adrienne
- Seynaeve C
- Shah Sohela
- Shapira Iuliana
- Sharma Priyanka
- Sharma Raghwa
- Shelling Andrew
- Shen Howard C
- Sherman Mark E
- Shu Xiao-Ou
- Shvetsov Yurii B
- Siddiqui Nadeem
- Side Lucy
- Side Lucy E
- Sieh Weiva
- Siesling S
- Sighoko Dominique
- Simard Jacques
- Simpson Peter
- Singer Christian F
- Sinilnikova Olga
- Skytte Anne-Bine
- Slager Susan
- Small Laurie
- Smalley Sarah
- Snadden Lesley
- Snyder Carrie L
- Sobol Hagay
- Sokolenko Anna P
- Sokolowska Johanna
- Solanes Ares
- Soller Maria
- Song Honglin
- Soubrier Florent
- Soucy Penny
- Southey Melissa
- Spindler Tassja J
- Spurdle Amanda
- Stayner Barbara
- Steele Linda
- Steinemann Doris
- Stenmark-Askmalm Marie
- Stevens Kristen
- Stoppa-Lyonnet Dominique
- Sucheston Lara
- Sukiennicki Grzegorz
- Sunde Lone
- Suthers Graeme
- Sutter Christian
- Sykes Pamela
- Szabo Csilla I
- Tancredi Mariella
- Tangen Ingvild L
- Tassell Margaret
- Taylor Amy
- Taylor Donna
- Taylor Jane
- Taylor Jessica
- Taylor Natalie
- Tchatchou Sandrine
- Tea Muy-Kheng
- Teixeira Manuel R
- Tejada Maria-Isabel
- Teo Soo-Hwang
- Terry Kathryn L
- Terry Mary Beth
- Teule Alex
- Thames N E
- Thierry Benjamin
- Thomas Susan
- Thomassen Mads
- Thompson Ella
- Thompson Pamela J
- Thorne Heather
- Tibiletti Maria Grazia
- Tihomirova Laima
- Tilanus-Linthorst Madeleine A
- Timorek Agnieszka
- Tirapo Carole
- Tischkowitz Marc
- Tizzoni Laura
- Tobias Ed
- Tognazzo Silvia
- Toland Amanda Ewart
- Tollenaar R A E M
- Toloczko-Grabarek Aleksandra
- Tommasi Stefania
- Tornero Eva
- Torres Diana
- Toulas Christine
- Townshend Sharron
- Trainer Alison
- Tran Lan
- Tripathi Vishakha
- Tsai Ya-Yu
- Tucker Kathy
- Tung Nadine
- Tworoger Shelley S
- Tyler Janet
- Tyrer Jonathan
- Uhrhammer Nancy
- van Altena Anne M
- van Asperen C J
- van Asperen Christi J
- van Cronenburg T C T E F
- van den Ouweland A M W
- van den Ouweland Ans M W
- van der Baan Frederieke H
- van der Hout A H
- van der Hout Annemarie H
- van der Luijt R B
- van der Luijt Rob B
- van der Pol C C
- van Deurzen C H M
- van Deurzen Carolien H M
- van Dooren Marieke F
- Van Le Linda
- van Leeuwen F E
- van Leeuwen Flora E
- Van Nieuwenhuysen Els
- van Os T A M
- van Os Theo A M
- van Rensburg Elizabeth J
- van Roozendaal K E P
- Varesco Liliana
- Varon-Mateeva Raymonda
- Vasen H F
- Vasen Hans F A
- Vaszko Tibor
- Vaur Dominique
- Vega Ana
- Velasco Angela
- Venat-Bouvet Laurence
- Vennin Philippe
- Vergote Ignace
- Verhoef S
- Verhoef Senno
- Verloop J
- Verny-Pierre Carole
- Verp Marion
- Viel Alessandra
- Vierkant Robert A
- Vignolo-Lutati Francesca
- Vijai Joseph
- Visvader Jane
- Volorio Sara
- von Wachenfeldt Anna
- Vratimos Athanassios
- Væth Signe
- Vénat-Bouvet Laurence
- Waisfisz Q
- Waisfisz Quinten
- Wakeley Katie
- Walker Lisa
- Walker Logan
- Walpole Ian
- Walsh Christine
- Wang Chen
- Wang Xianshu
- Wang-Gohrke Shan
- Wappenschmidt Barbara
- Warcoin Mathilde
- Ward Robin
- Waring Paul
- Warner Bev
- Warren Graham
- Watt Catherine
- Weaver JoEllen
- Webb P
- Weber Bernhard H F
- Weber Rachel Palmieri
- Weitzel Jeffrey N
- Wentzensen Nicolas
- Whiteman David C
- Whittemore Alice S
- Wicklund Kristine G
- Wiggins Jennifer
- Wijnands R
- Wijnen J T
- Wijnen Juul T
- Wilkens Lynne R
- Williams Rachael
- Wilson Judy
- Winchester Lizzie
- Winship Ingrid
- Woo Yin-Ling
- Wu Anna H
- Wu Kathy
- Wu Xifeng
- Yang Hannah
- Young Mary Ann
- Zaffaroni Daniela
- Zhang Jing
- Zheng Wei
- Zheng Yonglan
- Zidan Jamal
- Zikan Michal
- Ziogas Argyrios
- Złowocka-Perłowska Elżbieta
- Öfverholm Anna
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2015
- Field of study
Predicted breast and ovarian cancer absolute risks for <i>BRCA1</i> mutation carriers at the 5<sup>th</sup>, 10<sup>th</sup>, 90<sup>th</sup>, and 95<sup>th</sup> percentiles of the combined SNP profile distributions.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- Agnès Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- Elżbieta Złowocka-Perłowska (204566)
- Emma McCann (395229)
- Encarna B. Gómez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina Aittomäki (89889)
- Laima Tihomirova (196713)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
<p>The minimum, maximum and average risks are also shown. Predicted cancer risks are based on the associations of known breast or ovarian cancer susceptibility loci (identified through GWAS) with cancer risk for <i>BRCA1</i> mutation carriers and loci identified through the present study. Breast cancer risks based on the associations with: 1q32, 10q25.3, 19p13, 6q25.1, 12p11, <i>TOX3</i>, 2q35, <i>LSP1</i>, <i>RAD51L1</i> (based on HR and minor allele frequency estimates from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen-1003212-t001" target="_blank">Table 1</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen-1003212-t002" target="_blank">Table 2</a>, and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen.1003212.s016" target="_blank">Table S4</a>) and <i>TERT </i><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen.1003212-Bojesen1" target="_blank">[31]</a>. Ovarian cancer risks based on the associations with: 9p22, 8q24, 3q25, 17q21, 19p13 (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen-1003212-t001" target="_blank">Table 1</a>) and 17q21.31, 4q32.3 (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen-1003212-t002" target="_blank">Table 2</a>). Only the top SNP from each region was chosen. Average breast and ovarian cancer risks were obtained from published data <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen.1003212-Antoniou10" target="_blank">[25]</a>. The methods for calculating the predicted risks have been described previously <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003212#pgen.1003212-Antoniou11" target="_blank">[28]</a>.</p
Mapping of the 17q21 locus.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- Agnès Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- Elżbieta Złowocka-Perłowska (204566)
- Emma McCann (395229)
- Encarna B. Gómez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina Aittomäki (89889)
- Laima Tihomirova (196713)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
<p><i>Top 3 panels:</i> P-values of association (−log<sub>10</sub> scale) with ovarian cancer risk for genotyped and imputed SNPs (1000 Genomes Project CEU), by chromosome position (b.37) at the 17q21 region, for <i>BRCA1</i>, <i>BRCA2</i> mutation carriers and combined. Results based on the kinship-adjusted score test statistic (1 d.f.). <i>Fourth panel:</i> Genes in the region spanning (43.4–44.9 Mb, b.37) and the location of the most significant genotyped SNPs (in red font) and imputed SNPs (in black font). <i>Bottom panel:</i> Pairwise r<sup>2</sup> values for genotyped SNPs on iCOG array in the 17q21 region covering positions (43.4–44.9 Mb, b.37).</p
Associations with breast or ovarian cancer risk for loci previously reported to be associated with cancer risk for <i>BRCA1</i> mutation carriers.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- Agnès Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- Elżbieta Złowocka-Perłowska (204566)
- Emma McCann (395229)
- Encarna B. Gómez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina Aittomäki (89889)
- Laima Tihomirova (196713)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
<p>Freq = frequency of allele 2 in unaffected <i>BRCA1</i> carriers.</p><p>HR = Per allele Hazard Ratio associated with allele 2, under a single disease risk model, unless specified.</p><p>r<sup>2</sup>: correlation between the SNP in the present study and the published SNP.</p>*<p>SNP not in <i>BRCA1</i> GWAS SNP allocation on iCOGS chip.</p>a<p>: rs13387042 was previously found to be associated only under the 2-df model.</p>b<p>: analysis under a competing risks model.</p
Analysis of associations with breast and ovarian cancer risk simultaneously (competing risks analysis) for SNPs found to be associated with breast or ovarian cancer.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- Agnès Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- Elżbieta Złowocka-Perłowska (204566)
- Emma McCann (395229)
- Encarna B. Gómez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina Aittomäki (89889)
- Laima Tihomirova (196713)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
- Publication date
- Field of study
<p>Analysis of associations with breast and ovarian cancer risk simultaneously (competing risks analysis) for SNPs found to be associated with breast or ovarian cancer.</p
Study design for selection of the SNPs and genotyping of <i>BRCA1</i> samples.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- Agnès Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- Elżbieta Złowocka-Perłowska (204566)
- Emma McCann (395229)
- Encarna B. Gómez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacqueline Eason (238727)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina Aittomäki (89889)
- Laima Tihomirova (196713)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
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<p>GWAS data from 2,727 <i>BRCA1</i> mutation carriers were analysed for associations with breast and ovarian cancer risk and 32,557 SNPs were selected for inclusion on the iCOGS array. A total of 11,705 <i>BRCA1</i> samples (after quality control (QC) checks) were genotyped on the 31,812 <i>BRCA1</i>-GWAS SNPs from the iCOGS array that passed QC. Of these samples, 2,387 had been genotyped at the SNP selection stage and are referred to as “stage 1” samples, whereas 9,318 samples were unique to the iCOGS study (“Stage 2” samples). Next, 17 SNPs that exhibited the most significant associations with breast and ovarian cancer were selected for genotyping in a third stage involving an additional 2,646 <i>BRCA1</i> samples (after QC).</p
Associations with SNPs at the novel 17q21 region with ovarian cancer risk for <i>BRCA1</i> and <i>BRCA2</i> mutation carriers.
- Author
- Adam Lee (395196)
- Adriana Lasa (196672)
- Agnès Hardouin (395232)
- Alain Calender (395231)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Murray (395230)
- Alex Teulé (395273)
- Alexander Miron (28179)
- Alexandra V. Stavropoulou (387774)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Andrea Gehrig (395248)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anna P. Sokolenko (395288)
- Anne-Bine Skytte (395263)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Antonis C. Antoniou (146788)
- Atocha Romero (395283)
- Ava Kwong (52115)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bella Kaufman (196589)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Bernhard H. F. Weber (162289)
- Beth Y. Karlan (184236)
- Bjarni A. Agnarsson (154067)
- Brita Arver (395252)
- Capucine Delnatte (395234)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Caroline Seynaeve (95368)
- Catherine Houghton (395226)
- Catherine M. Phelan (219497)
- Catherine Nogues (395235)
- Cecilia M. Dorfling (395285)
- Chen Wang (88408)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claude Houdayer (395237)
- Conxi Lazaro (3405329)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- D. Gareth Evans (154186)
- Daniel Barrowdale (395192)
- Daniel Tessier (395291)
- Daniel Vincent (395198)
- Daphne Gschwantler-Kaulich (395260)
- David E. Cohn (395255)
- David E. Goldgar (196718)
- Debra Frost (154160)
- Dezheng Huo (151859)
- Diana M. Eccles (219472)
- Dieter Niederacher (93623)
- Dominique Leroux (395238)
- Dominique Stoppa-Lyonnet (29241)
- Dorothea Gadzicki (238732)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Ed Dicks (395194)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- Elżbieta Złowocka-Perłowska (204566)
- Emma McCann (395229)
- Encarna B. Gómez Garcia (5654410)
- Esther M. John (107266)
- Etienne Rouleau (395239)
- Evgeny N. Imyanitov (395207)
- Fabienne Prieur (246641)
- Fergus J. Couch (146607)
- Finn C. Nielsen (206969)
- Fiona Douglas (154179)
- Flavio Lejbkowicz (196544)
- Flora E. van Leeuwen (248404)
- Francesca Damiola (5331)
- Frans B. L. Hogervorst (146390)
- François Bacot (395197)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulia Melloni (395243)
- Gord Glendon (146666)
- Gustavo C. Rodriguez (395256)
- Hagay Sobol (91961)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg Plendl (395250)
- Helen Gregory (395228)
- Heli Nevanlinna (83762)
- Helmut Deissler (196727)
- Hilmi Ozcelik (20185)
- Huw Dorkins (239925)
- Ian Campbell (205212)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene L. Andrulis (107262)
- Isabelle Coupier (292499)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
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- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jennifer T. Loud (395275)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Jocelyne Chiquette (21796)
- Joe Dennis (395193)
- Joellen Weaver (395282)
- Johannes J. P. Gille (395216)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judith Balmaña (395210)
- Judy Garber (59512)
- Julian Adlard (395223)
- Julie Cunningham (395292)
- Juul T. Wijnen (154144)
- Kara Sarrel (102421)
- Karen H. Lu (395290)
- Karin Kast (112042)
- Karoline B. Kuchenbaecker (395191)
- Katarzyna Durda (146758)
- Katarzyna Jaworska (146755)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- kConFab Investigators (2615518)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristen Stevens (121411)
- Kristiina Aittomäki (89889)
- Laima Tihomirova (196713)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laurence Venat-Bouvet (395240)
- Laurent Castera (38087)
- Laurie Small (395257)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Lucy E. Side (395225)
- Mads Thomassen (395200)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Margreet G. E. M. Ausems (280984)
- Maria A. Caligo (154069)
- Maria Grazia Tibiletti (395246)
- Marie Stenmark-Askmalm (395253)
- Marinus J. Blok (395217)
- Marion Gauthier-Villars (238630)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mark T. Rogers (395227)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Mary S. Beattie (395206)
- Matthew Kosel (395195)
- Matti A. Rookus (154108)
- Melissa C. Southey (89921)
- Mercedes Duran (5651374)
- Mette K. Andersen (395271)
- Mia M. Gaudet (146621)
- Michael Friedlander (55581)
- Miguel de la Hoya (238670)
- Miquel Angel Pujana (395274)
- Muy-Kheng Tea (308359)
- Mélanie Léoné (395241)
- Nadine Tung (238710)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane M. Lindor (163048)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascal Pujol (8444)
- Pascaline Berthet (395233)
- Patricia A. Ganz (395212)
- Patrick J. Morrison (395224)
- Paul A. James (130908)
- Penny Soucy (21792)
- Per Hall (23544)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Richard Rosenquist (262592)
- Rita Katharina Schmutzler (395199)
- Rosa B. Barkardottir (238688)
- Rosalind A. Eeles (194860)
- Sabine Preisler-Adams (395251)
- Salina B. Chan (395287)
- Sandra Orsulic (184242)
- Sanne Traasdahl Moeller (395266)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Senno Verhoef (395219)
- Shani Shimon Paluch (395262)
- Sharon R. Sand (395278)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Soo-Hwang Teo (266270)
- Stefanie Engert (112037)
- Stephanie V. Blank (132743)
- Steve Ellis (395221)
- Steven A. Narod (230773)
- Steven Hart (395293)
- Sue Healey (41187)
- Susan J. Ramus (205214)
- Susan L. Neuhausen (238692)
- Susan L. Slager (223846)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Tara M. Friebel (395289)
- Taru A. Muranen (395284)
- Theo A. M. van Os (395220)
- Thomas V. O. Hansen (395201)
- Tibor Vaszko (395281)
- Timothy R. Rebbeck (230766)
- Tomasz Huzarski (395242)
- Tomi Pastinen (15737)
- Torben A. Kruse (92928)
- Trinidad Caldes (3147195)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Valeria Pensotti (395247)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Yves-Jean Bignon (54433)
- Zachary Fredericksen (146612)
- Zakaria Einbeigi (395254)
- Publication venue
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*<p>HRs estimated under the single disease risk model.</p