Fatal lymphoproliferation and acute monocytic leukemia-like disease following infectious mononucleosis in the elderly

Three elderly patients are reported, in whom serologically confirmed recent infectious mononucleosis is followed by fatal lymphoproliferation (case 1), by acute monocytic leukemia (case 2), and by acute probably monocytic leukemia (case 3)

MultiNet: Real-time Joint Semantic Reasoning for Autonomous Driving

While most approaches to semantic reasoning have fo- cused on improving performance, in this paper we argue that computational times are very important in order to en- able real time applications such as autonomous driving. To- wards this goal, we present an approach to joint classifi- cation, detection and semantic segmentation via a unified architecture where the encoder is shared amongst the three tasks. Our approach is very simple, can be trained end-to- end and performs extremely well in the challenging KITTI dataset, outperforming the state-of-the-art in the road seg- mentation task. Our approach is also very efficient, allow- ing us to perform inference at more then 23 frames per sec- ond. Training scripts and trained weights to reproduce our results can be found here: https://github.com/ MarvinTeichmann/MultiNetBegabtenstiftung Informatik Karlsruhe, ONR-N00014- 14-1-0232, Qualcomm, Samsung, NVIDIA, Google, EP- SRC and NSER

Three strongly correlated charged bosons in a one-dimensional harmonic trap: natural orbital occupancies

We study a one-dimensional system composed of three charged bosons confined in an external harmonic potential. More precisely, we investigate the ground-state correlation properties of the system, paying particular attention to the strong-interaction limit. We explain for the first time the nature of the degeneracies appearing in this limit in the spectrum of the reduced density matrix. An explicit representation of the asymptotic natural orbitals and their occupancies is given in terms of some integral equations.Comment: 6 pages, 4 figures, To appear in European Physical Journal

An RNA in situ hybridization protocol optimized for monocot tissue

RNA in situ hybridization can be time-consuming and difficult to troubleshoot. Here, we provide an optimized protocol for maize leaf tissue, though it can be applied to other plant tissues such as shoot apical meristems, embryos, and floral organs. We generate three >100 bp unique antisense probes for each gene of interest and hybridize them to tissue sections

A dipolar self-induced bosonic Josephson junction

We propose a new scheme for observing Josephson oscillations and macroscopic quantum self-trapping phenomena in a toroidally confined Bose-Einstein condensate: a dipolar self-induced Josephson junction. Polarizing the atoms perpendicularly to the trap symmetry axis, an effective ring-shaped, double-well potential is achieved which is induced by the dipolar interaction. By numerically solving the three-dimensional time-dependent Gross-Pitaevskii equation we show that coherent tunneling phenomena such as Josephson oscillations and quantum self-trapping can take place. The dynamics in the self-induced junction can be qualitatively described by a two-mode model taking into account both s-wave and dipolar interactions.Comment: Major changes. Accepted for publication in EP

An open source software for analysis of dynamic contrast enhanced magnetic resonance images: UMMPerfusion revisited

Background: Perfusion imaging has become an important image based tool to derive the physiological information in various applications, like tumor diagnostics and therapy, stroke, (cardio-) vascular diseases, or functional assessment of organs. However, even after 20 years of intense research in this field, perfusion imaging still remains a research tool without a broad clinical usage. One problem is the lack of standardization in technical aspects which have to be considered for successful quantitative evaluation; the second problem is a lack of tools that allow a direct integration into the diagnostic workflow in radiology. Results: Five compartment models, namely, a one compartment model (1CP), a two compartment exchange (2CXM), a two compartment uptake model (2CUM), a two compartment filtration model (2FM) and eventually the extended Toft’s model (ETM) were implemented as plugin for the DICOM workstation OsiriX. Moreover, the plugin has a clean graphical user interface and provides means for quality management during the perfusion data analysis. Based on reference test data, the implementation was validated against a reference implementation. No differences were found in the calculated parameters. Conclusion: We developed open source software to analyse DCE-MRI perfusion data. The software is designed as plugin for the DICOM Workstation OsiriX. It features a clean GUI and provides a simple workflow for data analysis while it could also be seen as a toolbox providing an implementation of several recent compartment models to be applied in research tasks. Integration into the infrastructure of a radiology department is given via OsiriX. Results can be saved automatically and reports generated automatically during data analysis ensure certain quality control