1 research outputs found
Regular and stochastic behavior of Parkinsonian pathological tremor signals
Regular and stochastic behavior in the time series of Parkinsonian
pathological tremor velocity is studied on the basis of the statistical theory
of discrete non-Markov stochastic processes and flicker-noise spectroscopy. We
have developed a new method of analyzing and diagnosing Parkinson's disease
(PD) by taking into consideration discreteness, fluctuations, long- and
short-range correlations, regular and stochastic behavior, Markov and
non-Markov effects and dynamic alternation of relaxation modes in the initial
time signals. The spectrum of the statistical non-Markovity parameter reflects
Markovity and non-Markovity in the initial time series of tremor. The
relaxation and kinetic parameters used in the method allow us to estimate the
relaxation scales of diverse scenarios of the time signals produced by the
patient in various dynamic states. The local time behavior of the initial time
correlation function and the first point of the non-Markovity parameter give
detailed information about the variation of pathological tremor in the local
regions of the time series. The obtained results can be used to find the most
effective method of reducing or suppressing pathological tremor in each
individual case of a PD patient. Generally, the method allows one to assess the
efficacy of the medical treatment for a group of PD patients.Comment: 39 pages, 10 figures, 1 table Physica A, in pres