Julius Symposium 2017 - Harbers, MC.pptx

Poster showing research protocol for systematic review and meta-analysis investigating effective nudging strategies for promoting healthy food choice

Additional file 3: of Gene-specific DNA methylation profiles and LINE-1 hypomethylation are associated with myocardial infarction risk

Supplemental Figures S1, S2, S3, and S4. Figure S1. quantile-quantile plot, EPICOR overall subjects. Figure S2. quantile-quantile plot, EPICOR men. Figure S3. quantile-quantile plot, EPICOR women. Figure S4. locations of ZBTB12 and LINE-1 CpG sites investigated by Sequenom MassARRAY. CpGs (in red) investigated within ZBTB12-DMR, LINE-1, and flanking primers (upper case: complementary to DNA; lower case: T7-promoter sequence and 10mer tag). CpG sites that could not be tested individually due to MassARRAY technology constrains, but had to be tested jointly with neighboring CpGs as a single unit, are underlined: the methylation level is the cumulative value of all the sites within the CpG unit. (ZIP 91 kb

Additional file 1: of Gene-specific DNA methylation profiles and LINE-1 hypomethylation are associated with myocardial infarction risk

Supplementary methods. A document with supplementary materials, including the following: (1) subjects: cohort details; lifestyle, anthropometrics, and biochemical measurements; and outcome definition; (2) laboratory methods: EPICOR sample preparation; discovery phase: Illumina Human450K Methylation Assay; replication phase on EPIC-NL sample: Sequenom MassARRAY; and (3) supplementary statistical methods: case-control differential methylation; removal of technical biases; DNA methylation and MI risk; DNA methylation and time to disease (TTD); supplementary references. (DOCX 73 kb

Additional file 1: Table S1. of Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

Discovery results for all models that passed replication thresholds for MEF analysis. Column header definitions provided at the end. Table S2. Discovery results for all models that passed replication thresholds for Biofilter analysis. Column header definitions provided at the end. (PDF 1649 kb