496 research outputs found

    Giroux, Still Raging for Humanity

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    A Conversation with DeCesare: Toward Practical Definitions of Critical Thinking

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    In response to conversations of Psychology teachers in Volume I of Pedagogy and the Human Sciences (2009), Michael DeCesare (2009) called for more specific definitions of the term “critical thinking.” DeCesare questioned methods of stimulating critical thinking in the classroom that might frustrate students of psychology without furthering their learning. DeCesare also appeared to view political realities in the academy as less relevant to the teaching of diversity courses than to the personal experiences of teachers. DeCesare seems to the present authors to believe that students should be moved or transformed to engage in social change through their courses in psychology. For DeCesare the process of learning facts appears to precede the process of critical thinking about psychology. Thus, the present authors have been presented with a challenge to show that there is a pedagogically practical and useful realm of “critical thinking” that can take place along with “factual,” empirical thinking in psychology. This paper, a conversation with DeCesare as he critiques the discourses presented in Volume I of Pedagogy and the Human Sciences, presents some of the ways critical theorists have defined critical thinking. With this presentation, we introduce the perspectives of contributors to Volume II of Pedagogy and the Human Sciences as each advances his or her own functional ideas about definitions and methods of critical thinking in the teaching of psychology

    Critical and Discursive Teaching in Psychology

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    American youth are more adept at multi-tasking and multi-processing the fast-paced media and technology information than prior generations (Glasl, 1999; Prensky, 2001). During this new wave of “post-modernism,” youth can interact globally with a far more culturally diverse yet interdependent society. Questioning, risk-taking, conflict resolution, and continuous innovation are the systems-level skills required to live and prosper. These skills should be integrated with more “modernist” skills, such as learning the truths of one’s field as the teachers of that field present them. This paper presents an example of how teaching about conflict can be used to help students critically examine the massive amount of information available to them, and understand the socially, historically, and politically situated nature of truth. Implications of standardization, critical discourse, and discursive teaching that bring real life problems and conflicts into the education process are discussed

    Teaching the Diversity Course in Conservative Times

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    This paper describes how conservative shifts in American political thinking can obstruct discussions about race, ethnicity and culture in so-called “diversity” and multicultural courses in academic psychology. The authors, both teachers of psychology, examine the serious implications that a shifting political landscape presents for courses on race, ethnicity, gender and culture. Classroom techniques that may counter the reality of conservative action in the Academy are discussed, including some methods for continuing to deepen the meaning that psychology students take from the examination of multicultural topics. For the present authors, diversity and multi-cultural courses, particularly in psychology, must continue to include cultural sensitivity, belief in the essential importance of community research which includes the perspectives of “the other”, and constant, painstaking self-examination on the part of the teacher (Ridley, 2005). However, the very ground on which this assumption has rested for the last thirty or so years is moving and shifting under our very feet. It is hoped that the experiences of the authors teaching “the diversity course” can support others who seek to keep teaching similar courses even as the shadow of conservatism lengthens

    Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition

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    <p>Abstract</p> <p>Background</p> <p>Epithelial to mesenchymal transition (EMT), implicated as a mechanism for tumor dissemination, is marked by loss of E-cadherin, disruption of cell adhesion, and induction of cell motility and invasion. In most intraductal breast carcinomas E-cadherin is regulated epigenetically via methylation of the promoter. E-cadherin expression is therefore dynamic and open to modulation by the microenvironment. In addition, it has been observed that metastatic foci commonly appear more differentiated than the primary tumor, suggesting that cancer cells may further undergo a mesenchymal to epithelial reverting transition (MErT) in the secondary organ environment following the EMT that allows for escape.</p> <p>Results</p> <p>We first examined E-cadherin expression in primary breast tumors and their corresponding metastases to liver, lung and brain and discovered that 62% (10/16) of cases showed increased E-cadherin expression in the metastases compared to the primaries. These observations led to the question of whether the positive metastatic foci arose from expansion of E-cadherin-positive cells or from MErT of originally E-cadherin-negative disseminated cells. Thus, we aimed to determine whether it was possible for the mesenchymal-like MDA-MB-231 breast cancer cells to undergo an MErT through the re-expression of E-cadherin, either through exogenous introduction or induction by the microenvironment. Ectopic expression of full-length E-cadherin in MDA-MB-231 cells resulted in a morphological and functional reversion of the epithelial phenotype, with even just the cytosolic domain of E-cadherin yielding a partial phenotype. Introduction of MDA-MB-231 cells or primary explants into a secondary organ environment simulated by a hepatocyte coculture system induced E-cadherin re-expression through passive loss of methylation of the promoter. Furthermore, detection of E-cadherin-positive metastatic foci following the spontaneous metastasis of MDA-MB-231 cells injected into the mammary fat pad of mice suggests that this re-expression is functional.</p> <p>Conclusions</p> <p>Our clinical observations and experimental data indicate that the secondary organ microenvironment can induce the re-expression of E-cadherin and consequently MErT. This phenotypic change is reflected in altered cell behavior and thus may be a critical step in cell survival at metastatic sites.</p

    Empirical aspects of record linkage across multiple data sets using statistical linkage keys: the experience of the PIAC cohort study

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    Background. In Australia, many community service program data collections developed over the last decade, including several for aged care programs, contain a statistical linkage key (SLK) to enable derivation of client-level data. In addition, a common SLK is now used in many collections to facilitate the statistical examination of cross-program use. In 2005, the Pathways in Aged Care (PIAC) cohort study was funded to create a linked aged care database using the common SLK to enable analysis of pathways through aged care services. Linkage using an SLK is commonly deterministic. The purpose of this paper is to describe an extended deterministic record linkage strategy for situations where there is a general person identifier (e.g. an SLK) and several additional variables suitable for data linkage. This approach can allow for variation in client information recorded on different databases. Methods. A stepwise deterministic record linkage algorithm was developed to link datasets using an SLK and several other variables. Three measures of likely match accuracy were used: the discriminating power of match key values, an estimated false match rate, and an estimated step-specific trade-off between true and false matches. The method was validated through examining link properties and clerical review of three samples of links. Results. The deterministic algorithm resulted in up to an 11% increase in links compared with simple deterministic matching using an SLK. The links identified are of high quality: validation samples showed that less than 0.5% of links were false positives, and very few matches were made using non-unique match information (0.01%). There was a high degree of consistency in the characteristics of linked events. Conclusions. The linkage strategy described in this paper has allowed the linking of multiple large aged care service datasets using a statistical linkage key while allowing for variation in its reporting. More widely, our deterministic algorithm, based on statistical properties of match keys, is a useful addition to the linker's toolkit. In particular, it may prove attractive when insufficient data are available for clerical review or follow-up, and the researcher has fewer options in relation to probabilistic linkage

    Self-efficacy of direct care workers providing care to older people in residential aged care settings : a scoping review protocol

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    Background: Self-efficacy is developed through a person’s interaction with his/her physical and social environment. Self-efficacy in caring is an essential attribute of care workers to develop a positive attitude towards their clients, improve work performance, and enhance job satisfaction. Care workers’ self-efficacy may vary according to the context in which the care is being provided. Aged care is a multidimensional and challenging setting, and characteristics of aged care services are different from those of acute care services. The objective of this review is to give an overview of the self-efficacy of residential aged care workers in caring for older people and factors influencing their self-efficacy. Methods: The protocol for this review is based on the Joanna Briggs Institute Reviewer’s Manual for Scoping Review. A systematic search of the literature on electronic databases MEDLINE, PsycINFO, CINAHL, AgeLine, SCOPUS, and ProQuest Dissertations and Theses Global will be carried out using predefined search terms to identify relevant studies. This review will include studies that examined the self-efficacy of direct care workers in caring for older people living in residential aged care facilities. All primary studies irrespective of the study design will be included. Studies conducted to develop measures or studies with informal care workers or students as study participants will not be considered. Two reviewers will independently conduct title and abstract screening, full-text screening, and data charting. A third reviewer will resolve discrepancies, while the final decision for conflicting studies will be made by consensus within the review team. Descriptive statistics will be utilized to analyze the quantitative findings, and the result will be presented in narrative form accompanied by tables and charts. Content analysis will be carried to analyze the qualitative findings and will be presented in narrative form supported by illustrative quotations. Discussion: This study will be an important source of knowledge to policymakers and aged care providers to understand the self-efficacy of aged care workers to support and enhance their self-efficacy and thereby improve their caring behaviors towards their clients. Scoping review registration: Joanna Briggs Institute Systematic Review Register with the title “A scoping review of factors influencing caring efficacy of direct care workers providing care to older people”. © 2021, The Author(s)

    Bovine Spongiform Encephalopathy Infectivity in Greater Kudu (Tragelaphus strepsiceros)

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    Of all the species exposed naturally to the bovine spongiform encephalopathy (BSE) agent, the greater kudu (Tragelaphus strepsiceros), a nondomesticated bovine from Africa, appears to be the most susceptible to the disease. We present the results of mouse bioassay studies to show that, contrary to findings in cattle with BSE in which the tissue distribution of infectivity is the most limited recorded for any of the transmissible spongiform encephalopathies (TSE), infectivity in greater kudu with BSE is distributed in as wide a range of tissues as occurs in any TSE. BSE agent was also detected in skin, conjunctiva, and salivary gland, tissues in which infectivity has not previously been reported in any naturally occurring TSE. The distribution of infectivity in greater kudu with BSE suggests possible routes for transmission of the disease and highlights the need for further research into the distribution of TSE infectious agents in other host species
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