Tuok5 dans le dialecte de Fuzhou

The object of this paper is to establish the syntactic function, in the Fuzhou dialect, of the phenomenon of tonal and consonantal sandhis. The existence of sandhis in this dialect was described a long time ago (Maclay, 1870), but no systematic analysis of their syntactic role has been made until now. Former researchers mostly confined themselves to the fact that sandhis existed at the morpheme frontiers in dissyllabic words. Here, through the homophonic words all represented by the syllable "tuok" , whose syntactic functions are marked by whether or not they use sandhis, we are trying to detach the syntactic role of tonal and consonantal sandhis, by exploring the possibilities of their use in relation with the various functions of the words "tuok".Désirat Michel, Liang Yuzhang. Tuok5 dans le dialecte de Fuzhou. In: Cahiers de linguistique - Asie orientale, vol. 19 1, 1990. pp. 35-59

Sodium butyrate promotes the differentiation of rat bone marrow mesenchymal stem cells to smooth muscle cells through histone acetylation.

Establishing an effective method to improve stem cell differentiation is crucial in stem cell transplantation. Here we aimed to explore whether and how sodium butyrate (NaB) induces rat bone marrow mesenchymal stem cells (MSCs) to differentiate into bladder smooth muscle cells (SMCs). We found that NaB significantly suppressed MSC proliferation and promoted MSCs differentiation into SMCs, as evidenced by the enhanced expression of SMC specific genes in the MSCs. Co-culturing the MSCs with SMCs in a transwell system promoted the differentiation of MSCs into SMCs. NaB again promoted MSC differentiation in this system. Furthermore, NaB enhanced the acetylation of SMC gene-associated H3K9 and H4, and decreased the expression of HDAC2 and down-regulated the recruitment of HDAC2 to the promoter regions of SMC specific genes. Finally, we found that NaB significantly promoted MSC depolarization and increased the intracellular calcium level of MSCs upon carbachol stimulation. These results demonstrated that NaB effectively promotes MSC differentiation into SMCs, possibly by the marked inhibition of HDAC2 expression and disassociation of HDAC2 recruitment to SMC specific genes in MSCs, which further induces high levels of H3K9ace and H4ace and the enhanced expression of target genes, and this strategy could potentially be applied in clinical tissue engineering and cell transplantation

A Novel Hybrid Model of WRF and Clearness Index-Based Kalman Filter for Day-Ahead Solar Radiation Forecasting

Day-ahead forecasting of solar radiation is essential for grid balancing, real-time unit dispatching, scheduling and trading in the solar energy utilization system. In order to provide reliable forecasts of solar radiation, a novel hybrid model is proposed in this study. The hybrid model consists of two modules: a mesoscale numerical weather prediction model (WRF: Weather Research and Forecasting) and Kalman filter. However, the Kalman filter is less likely to predict sudden changes in the forecasting errors. To address this shortcoming, we develop a new framework to implement a Kalman filter based on the clearness index. The performance of this hybrid model is evaluated using a one-year dataset of solar radiation taken from a photovoltaic plant located at Maizuru, Japan and Qinghai, China, respectively. The numerical results reveal that the proposed hybrid model performs much better in comparison with the WRF-alone forecasts under different sky conditions. In particular, in the case of clear sky conditions, the hybrid model can improve the forecasting accuracy by 95.7% and 90.9% in mean bias error (MBE), and 42.2% and 26.8% in root mean square error (RMSE) for Maizuru and Qinghai sites, respectively

Plasmonic Resonance Coupling of Nanodisk Array/Thin Film on the Optical Fiber Tip for Integrated and Miniaturized Sensing Detection

Fiber-optic surface plasmon resonance (FOSPR) sensing technology has become an appealing candidate in biochemical sensing applications due to its distinguished capability of remote and point-of-care detection. However, FOSPR sensing devices with a flat plasmonic film on the optical fiber tip are seldom proposed with most reports concentrating on fiber sidewalls. In this paper, we propose and experimentally demonstrate the plasmonic coupled structure of a gold (Au) nanodisk array and a thin film integrated into the fiber facet, enabling the excitation of the plasmon mode on the planar gold film by strong coupling. This plasmonic fiber sensor is fabricated by the ultraviolet (UV) curing adhesive transferring technology from a planar substrate to a fiber facet. The experimental results demonstrate that the fabricated sensing probe has a bulk refractive index sensitivity of 137.28 nm/RIU and exhibits moderate surface sensitivity by measuring the spatial localization of its excited plasmon mode on Au film by layer-by-layer self-assembly technology. Furthermore, the fabricated plasmonic sensing probe enables the detection of bovine serum albumin (BSA) biomolecule with a detection limit of 19.35 μM. The demonstrated fiber probe here provides a potential strategy to integrate plasmonic nanostructure on the fiber facet with excellent sensing performance, which has a unique application prospect in the detection of remote, in situ, and in vivo invasion

Thermoresponsive Ultrathin Membranes with Precisely Tuned Nanopores for High-Flux Separation

With the growing demand for small- and large-scale bioprocesses, advanced membranes with high energy efficiency are highly required. However, conventional polymer-based membranes often have to sacrifice selectivity for permeability. In this work, we report the fabrication of a thermoresponsive composite ultrathin membrane with precisely controlled nanopores for high-throughput separation. The composite membrane is made by grafting a PEG analogue thermoresponsive copolymer onto an ultrathin single-wall carbon nanotubes (SWCNTs) membrane via π–π interaction with no use of the common “grafting from” synthesis approach. The composite membrane exhibits ultrahigh water permeation flux as high as 6430 L m^–2 h^–1 at 40 °C, and more importantly, the pore size of the membrane could be finely adjusted by utilizing the thermoresponsive property of the grafted copolymer. With the temperature changing below and above the lower critical solution temperature (LCST) of the copolymer, the effective pore size of the membrane can be tuned precisely between approximately 12 and 14 nm, which could be applied to effectively separate materials with very small size differences through size sieving

Thymine-Functionalized Gold Nanoparticles (Au NPs) for a Highly Sensitive Fiber-Optic Surface Plasmon Resonance Mercury Ion Nanosensor

Mercury ion (Hg2+) is considered to be one of the most toxic heavy metal ions. Once the content of Hg2+ exceeds the quality standard in drinking water, the living environment and health of human beings will be threatened and destroyed. Therefore, the establishment of simple and efficient methods for Hg2+ ion detection has important practical significance. In this paper, we present a highly sensitive and selective fiber-optic surface plasmon resonance (SPR) Hg2+ ion chemical nanosensor by designing thymine (T)-modified gold nanoparticles (Au NPs/T) as the signal amplification tags. Thymine-1-acetic acid (T-COOH) was covalently coupled to the surface of 2-aminoethanethiol (AET)-modified Au NPs and Au film by 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride/N-Hydroxysuccinimide (EDC/NHS) activation effect, respectively. In the presence of Hg2+ ions, the immobilized thymine combines specifically with Hg2+ ions, and forms an Au/thymine-Hg2+-thymine/Au (Au/T-Hg2+-T/Au) complex structure, leading to a shift in SPR wavelength due to the strong electromagnetic couple between Au NPs and Au film. Under optimal conditions, the proposed sensor was found to be highly sensitive to Hg2+ in the range of 80 nM–20 µM and the limit of detection (LOD) for Hg2+ was as low as 9.98 nM. This fiber-optic SPR sensor afforded excellent selectivity for Hg2+ ions against other heavy metal ions such as Fe3+, Cu2+, Ni2+, Ba2+, K+, Na+, Pb2+, Co2+, and Zn2+. In addition, the proposed sensor was successfully applied to Hg2+ assay in real environmental samples with excellent recovery. Accordingly, considering its simple advantages, this novel strategy provides a potential platform for on-site determination of Hg2+ ions by SPR sensor