N=1{\cal N}=1 superfield description of BPS solutions in 6D gauged SUGRA with 3-branes

We provide ${\cal N}=1$ superfield description of BPS backgrounds in six-dimensional supergravity (6D SUGRA) with 3-branes, which is compactified on a two-dimensional space. The brane terms induce the localized fluxes. We find a useful gauge in which the background equations become significantly simple. This is not the Wess-Zumino gauge, and the relation to the usual component-field expression of 6D SUGRA is not straightforward. One of the equations reduces to the Liouville equation. By moving to the Wess-Zumino gauge, we check that our expressions reproduce the known results of the previous works, which are expressed in the component fields. Our results help us develop the systematic derivation of four-dimensional effective theories that keeps the ${\cal N}=1$ SUSY structure.Comment: 32 pages, no figures, published versio

Requirement for Dicer in Maintenance of Monosynaptic Sensory-Motor Circuits in the Spinal Cord

SummaryIn contrast to our knowledge of mechanisms governing circuit formation, our understanding of how neural circuits are maintained is limited. Here, we show that Dicer, an RNaseIII protein required for processing microRNAs (miRNAs), is essential for maintenance of the spinal monosynaptic stretch reflex circuit in which group Ia proprioceptive sensory neurons form direct connections with motor neurons. In postnatal mice lacking Dicer in proprioceptor sensory neurons, there are no obvious defects in specificity or formation of monosynaptic sensory-motor connections. However, these circuits degrade through synapse loss and retraction of proprioceptive axonal projections from the ventral spinal cord. Peripheral terminals are also impaired without retracting from muscle targets. Interestingly, despite these central and peripheral axonal defects, proprioceptive neurons survive in the absence of Dicer-processed miRNAs. These findings reveal that Dicer, through its production of mature miRNAs, plays a key role in the maintenance of monosynaptic sensory-motor circuits

Zn-induced wipeout effect on Cu NQR spectra in La2−x_{2-x}Srx_xCu1−y_{1-y}Zny_yO4_4

We report a systematic study of Zn-substitution effect on Cu NQR spectrum for high $T_c$ superconductors La$_{2-x}$Sr$_x$Cu$_{1-y}$Zn$_y$O$_4$ from carrier-underdoped to -overdoped regimes (polycrystalline samples, $x$ =0.10, 0.15, and 0.20). We observed no appreciable wipeout effect for the overdoped samples, a gradual and partial wipeout effect below about 80 K for the optimally doped ones, and very abrupt and full wipeout effect below about 40 K for the underdoped ones. The wipeout effect indicates a highly enhanced spectral weight of Cu spin fluctuations at a low frequency. We associate the wipeout effect with a Zn-induced local magnetism far above 40 K and with a localization effect below 40 K.Comment: 2 pages, 3 figures, accepted for publication in Physica C (LT23, Hiroshima 2002

Agreement between continuous cardiac output measured by the fourth-generation FloTrac/Vigileo system and a pulmonary artery catheter in adult liver transplantation

In liver transplantation for end-stage liver failure, monitoring of continuous cardiac output (CCO) is used for circulatory management due to hemodynamic instability. CCO is often measured using the minimally invasive FloTrac/Vigileo system (FVS-CCO), instead of a highly invasive pulmonary artery catheter (PAC-CCO). The FVS has improved accuracy due to an updated cardiac output algorithm, but the effect of this change on the accuracy of FVS-CCO in liver transplantation is unclear. In this study, we assessed agreement between fourth-generation FVS-CCO and PAC-CCO in 20 patients aged ≥ 20 years who underwent scheduled or emergency liver transplantation at Kyoto University Hospital from September 2019 to June 2021. Consent was obtained before surgery and data were recorded throughout the surgical period. Pearson correlation coefficient (r), Bland–Altman and 4-quadrant plot analyses were performed on the extracted data. A total of 1517 PAC-CCO vs. FVS-CCO data pairs were obtained. The mean PAC-CCO was 8.73 L/min and the mean systemic vascular resistance was 617.5 dyne·s·cm⁻⁵, r was 0.48, bias was 1.62 L/min, the 95% limits of agreement were − 3.04 to 6.27, and the percentage error was 54.36%. These results show that agreement and trending between fourth-generation FVS-CCO and PAC-CCO are low in adult liver transplant recipients

マウスガードの自律神経活動への影響 : 瞳孔フラッシュ応答による定量的評価

Background:Recently, it has been reported that mouth guards (MGs), which reduce the incidence and severity of traumatic oral injuries in contact sports, may actually affect sports performance. We have observed that a majority of subjects showed improved dynamic visual acuity during head rotation when using a MG, but subjects who were unwilling to use a MG showed the opposite effect. Thus, we hypothesized that unpleasant sensations due to MGs may decrease sports performance.Methods:In this study, we measured autonomic nervous system activity to evaluate unpleasant sensations objectively and quantitatively by measuring the pupillary flash response (PFR) and heart rate variability (HRV), before, during, and after wearing 3- and 5-mm-thick custom-made MGs in 10 healthy subjects.Results:It was found that the 5-mm MG had a higher incidence of unpleasant sensations (50% of subjects) than did the 3-mm MG (10%). PFR (not HRV) analysis showed that both sympathetic and parasympathetic nervous system activities increased in subjects with unpleasant sensations.Conclusions:We suggest that the unpleasant sensation induced this unusual autonomic nervous system response, which could not be detected by traditional methods such as HRV analysis. By using PFR analysis, it is possible to make MGs without unpleasant sensations for better sports performance.博士（医学）・乙第1306号・平成24年11月27日Copyright © 2012 Japanese Stomatological Society. Published by Elsevier Japan K