Receiver operating characteristic curve analysis using serum microRNAs ((A) miR-7, (B) miR-34a, (C) miR-181d, (D) miR-193b) for distinguishing PDAC from AIP.

<p>Receiver operating characteristic curve analysis using serum microRNAs ((A) miR-7, (B) miR-34a, (C) miR-181d, (D) miR-193b) for distinguishing PDAC from AIP.</p

Serum expression of miRNAs in patients with pancreatic diseases.

<p>Scatter plots of serum miRNA expression in AIP (n = 15), IPMN (n = 26) and PDAC patients (n = 69). The Y-axis represents the relative expression of the miRNAs normalized to cel-miR-39. The line represents the median value. The significance of differences was determined using Mann-Whitney test (***P < .001: **P < .01). (A) miR-7 expression. (B) miR-34a expression. (C) miR-181d expression. (D) miR-193b expression. AIP, autoimmune pancreatitis; IPMN, intraductal papillary mucinous neoplasm; PDAC, pancreatic ductal adenocarcinoma.</p

Serum miRNA expression in PDAC at different Tumor Node Metastasis (TNM) stages.

<p>The Y-axis (log₁₀ scale) represents the relative expression of each miRNA normalized to cel-miR-39. Boxes represent the interquartile range, and the horizontal line across each box indicates the median value. The significance of differences was determined using Mann-Whitney test (**P < .01: *P < .05). (A) miR-7 expression. (B) miR-34a expression. (C) miR-181d expression. (D) miR-193b expression. PDAC, pancreatic ductal adenocarcinoma; AIP, autoimmune pancreatitis.</p