Gabriyel’in günahı

Charles Merouvel'in Tercüman-ı Hakikat'te yayımlanan Gabriyel’in Günahı adlı romanının ilk ve son tefrikalar

Additional file 1 of Comparison of clinical effectiveness and subsequent fertility between hysteroscopic resection and vaginal repair in patients with cesarean scar defect: a prospective observational study

Additional file 1: Supplementary Figure 1. Schematic presentation of ultrasound measurement of the niche. a: the base directed to the posterior wall of the cervical canal b: the apex pointing to the anterior wall of the niche. Supplementary Figure 2. Hysteroscopic resection. A: Hysteroscopic view of a defect at the anterior uterine wall. B: Resection of the lower rim using a resectoscope. C: Coagulation of the niche’s surface. D: Hysteroscopic view after resection. Supplemental Table 1. Clinical characteristics of patients attempting pregnancy

DataSheet_1_The impact of COVID lockdown on glycaemic control in paediatric patients with type 1 diabetes: A systematic review and meta-analysis of 22 observational studies.pdf

IntroductionThe COVID lockdown has posted a great challenge to paediatric patients with type 1 diabetes (T1D) and their caregivers on the disease management. This systematic review and meta-analysis sought to compare the glycaemic control among paediatric patients with T1D (aged under 18 years) pre- during, and post-lockdown period.Methods and materialsWe did a systematic search of three databases (PubMed, Embase, and the WHO COVID‐19 Global literature) for the literature published between 1 Jan 2019 to 10 Sep 2022. Studies meeting the following inclusion criteria were eligible for this study: (1) a COVID-19 related study; (2) inclusion of children aged 18 years old or under with established T1D; (3) comparing the outcomes of interest during or after the COVID lockdown with that before the lockdown. Study endpoints included mean difference (MD) in HbA1c, blood glucose, time in range (TIR, 70-180 mg/dl), time above range (TAR, >180mg/dl), time below range (TBR,ResultsInitial search identified 4488 records and 22 studies with 2106 paediatric patients with T1D were included in the final analysis. Compared with pre-lockdown period, blood glucose was significantly decreased by 0.11 mmol/L (95%CI: -0.18, -0.04) during lockdown period and by 0.42 mmol/L (95%CI: -0.73, -0.11) after lockdown. The improvement was also found for TIR, TAR, TBR, and CV during and post-lockdown (all p valuesConclusionCompared with pre-lockdown period, there was significant improvement in T1D paediatric patients’ glucose metrics during and post-lockdown. The underlying reasons for this positive impact warrant further investigation to inform future paediatric diabetes management.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42022359213.</p

The simulated scattering-parameters of the dual-band SIW filter in Fig 4.

<p>(a) The simulated scattering parameters (<i>S</i>₁₁ and <i>S</i>₂₁) correspond to the electromagnetic distributions in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0179816#pone.0179816.g004" target="_blank">Fig 4a–4d</a>. (b) The simulated scattering parameters correspond to the electromagnetic distributions in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0179816#pone.0179816.g004" target="_blank">Fig 4c and 4f</a>.</p

Modified Lactic Acid Bacteria Detect and Inhibit Multiresistant Enterococci

We designed <i>Lactococcus lactis</i> to detect <i>Enterococcus faecalis</i>. Upon detection, <i>L. lactis</i> produce and secrete antienterococcal peptides. The peptides inhibit enterococcal growth and reduce viability of enterococci in the vicinity of <i>L. lactis</i>. The enterococcal sex pheromone cCF10 serves as the signal for detection. Expression vectors derived from pCF10, a cCF10-responsive <i>E. faecalis</i> sex-pheromone conjugative plasmid, were engineered in <i>L. lactis</i> for the detection system. Recombinant host strains were engineered to express genes for three bacteriocins, enterocin A, hiracin JM79 and enterocin P, each with potent antimicrobial activity against <i>E. faecalis.</i> Sensitive detection and specific inhibition occur both in agar and liquid media. The engineered <i>L. lactis</i> also inhibited growth of multidrug-resistant <i>E. faecium</i> strains, when induced by cCF10. The presented vectors and strains can be components of a toolbox for the development of alternative antibiotic technologies targeting enterococci at the site of infection

The photograph of the proposed SIW filter PCB.

<p>The experiment contains different states and only one state (state 11/ <i>slot</i>_L = 28 mm) is showed in Fig 9. The interference slot length (<i>slot</i>_L) of the SIW filter is 28.0 mm. The changes in the interference slot length are achieved by copper. state 11 means all perturbation holes are connected to the top metal layer by solder.</p

The sensitivity analysis for the SIW filter in Fig 7.

<p>(a) The scattering parameters (<i>S</i>₁₁ and <i>S</i>₂₁) of the interference slot with different widths (<i>slot</i>_w) in each cavity. (b-c) The scattering parameters of a connected slot with different lengths (<i>Vslot</i>_L) and widths (<i>Vslot</i>_w) in each cavity, respectively.</p

The electromagnetic distributions of the TE₁₀₁ and the TE₁₀₂ modes in different perturbation states.

<p>The SIW filter is composed of two square cavities in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0179816#pone.0179816.g001" target="_blank">Fig 1</a>, (a-b) The two square cavities without any interference, (c-d) An interference slot with the length of <i>slot</i>_L on the vertical line of each square cavity, (e-f) Four perturbation via-holes on the vertical line of each cavity, (g-h) Three perturbation via-holes on each side of the vertical line of each square cavity.</p

The electromagnetic distributions of the dual-band SIW filter with the different perturbations.

<p>(a-b) Six perturbation via-holes and <i>slot</i>_<i>L</i> = 12.0 mm in each cavity. (c-d) Two perturbation via-holes and <i>slot</i>_<i>L</i> = 5.0 mm in each cavity. (e-f) Two perturbation via-holes and <i>slot</i>_<i>L</i> = 13.8 mm in each cavity.</p

The SIW filter with four perturbation holes surrounded by the connected slots in each cavity.

<p>The states of the perturbation holes corresponding to x are the same. The value of x is 1 when the corresponding perturbation holes are connected to the top metal layer, and vice versa.</p