Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles-0

Rix in Figure 2.<p><b>Copyright information:</b></p><p>Taken from "Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles"</p><p>http://www.biomedcentral.com/1471-2105/9/155</p><p>BMC Bioinformatics 2008;9():155-155.</p><p>Published online 20 Mar 2008</p><p>PMCID:PMC2322988.</p><p></p

<i>TLR-2</i> genotype patterns of the SNPs with heterozygosity rates >0.01.

<p>Each column represents a genotype pattern and each row a SNP in <i>TLR-2</i>. Common allele homozygote (blue), heterozygote (red) and rare allele homozygote (yellow) are shown.</p

Position of the four SNPs that had heterozygosity rates >0.01 in each TLR sequence.

<p>Position of the four SNPs that had heterozygosity rates >0.01 in each TLR sequence.</p

Genotypic analysis of the SNPs.

a<p><i>P</i> values <0.05 are shown in bold.</p>b<p>APN+ALN.</p>c<p>Statistical significance with correction for multiple-SNP testing (<i>P</i><0.0125).</p

MALDI-TOF mass spectra from the genotyping of <i>TLR-2</i> (rs3804100) PCR product and its sequencing results.

<p>(A) The SNPs were genotyped by MALDI-TOF MS based on the molecular weights of the mini-sequencing products listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058687#pone-0058687-t001" target="_blank">Table 1</a>. (B) Sequencing results for each of the PCR products from the C/T, T/T, and C/C genotypes of rs3804100. The SNPs are indicated by arrowheads.</p

Genotypic analysis of the SNPs in the no-VUR patient subgroup.

a<p><i>P</i> values <0.05 are shown in bold.</p>b<p>APN+ALN.</p>c<p>Statistical non-significance with correction for multiple-SNP testing (<i>P</i>>0.0125).</p

Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles-4

R2E, HCT_OPT and HCT_R2E. (a) Generalized anti-Robinson (GAR) loss scores. (b) Relative generalized anti-Robinson (RGAR) loss scores<p><b>Copyright information:</b></p><p>Taken from "Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles"</p><p>http://www.biomedcentral.com/1471-2105/9/155</p><p>BMC Bioinformatics 2008;9():155-155.</p><p>Published online 20 Mar 2008</p><p>PMCID:PMC2322988.</p><p></p

Allele frequency analysis of the SNPs using the logistic regression model.

a<p>APN+ALN.</p

Genotype pattern frequency analysis of the SNPs in <i>TLR-2</i> (rs3804099 and rs3804100) using the two-tailed Fisher’s Exact Test^#.

a<p><i>P</i> values <0.05 are shown in bold.</p>b<p>APN+ALN.</p>#<p>2×2 contingency table, <a href="http://www.vassarstats.net/tab2" target="_blank">http://www.vassarstats.net/tab2</a>×2.html.</p

Primers used for the amplification and mini-sequencing analysis of the SNPs.

<p>Primers used for the amplification and mini-sequencing analysis of the SNPs.</p