First detection of 22 GHz H2O masers in TX Camelopardalis

Simultaneous time monitoring observations of H$_{2}$O $6_{16}-5_{23}$, SiO $J$ = 1--0, 2--1, 3--2, and $^{29}$SiO $v$ = 0, $J$ = 1--0 lines were carried out in the direction of the Mira variable star TX Cam with the Korean VLBI Network single dish radio telescopes. For the first time, the H$_{2}$O maser emission from TX Cam was detected near the stellar velocity at five epochs from April 10, 2013 ($\phi$ = 3.13) to June 4, 2014 ($\phi$ = 3.89) including minimum optical phases. The intensities of H$_{2}$O masers are very weak compared to SiO masers. The variation of peak antenna temperature ratios among SiO $v$ = 1, $J$ = 1--0, $J$ = 2--1, and $J$ = 3--2 masers is investigated according to their phases. The shift of peak velocities of H$_{2}$O and SiO masers with respect to the stellar velocity is also investigated according to observed optical phases. The H$_{2}$O maser emission occurs around the stellar velocity during our monitoring interval. On the other hand, the peak velocities of SiO masers show a spread compared to the stellar velocity. The peak velocities of SiO $J$ = 2--1, and $J$ = 3--2 masers show a smaller spread with respect to the stellar velocity than those of SiO $J$ = 1--0 masers. These simultaneous observations of multi-frequencies will provide a good constraint for maser pumping models and a good probe for investigating the stellar atmosphere and envelope according to their different excitation conditions.Comment: 10 page

Selective inference for clustering with unknown variance

In many modern statistical problems, the limited available data must be used both to develop the hypotheses to test, and to test these hypotheses-that is, both for exploratory and confirmatory data analysis. Reusing the same dataset for both exploration and testing can lead to massive selection bias, leading to many false discoveries. Selective inference is a framework that allows for performing valid inference even when the same data is reused for exploration and testing. In this work, we are interested in the problem of selective inference for data clustering, where a clustering procedure is used to hypothesize a separation of the data points into a collection of subgroups, and we then wish to test whether these data-dependent clusters in fact represent meaningful differences within the data. Recent work by Gao et al. [2022] provides a framework for doing selective inference for this setting, where a hierarchical clustering algorithm is used for producing the cluster assignments, which was then extended to k-means clustering by Chen and Witten [2022]. Both these works rely on assuming a known covariance structure for the data, but in practice, the noise level needs to be estimated-and this is particularly challenging when the true cluster structure is unknown. In our work, we extend this work to the setting of noise with unknown variance, and provide a selective inference method for this more general setting. Empirical results show that our new method is better able to maintain high power while controlling Type I error when the true noise level is unknown

Simultaneous VLBI Astrometry of H2O and SiO Masers toward the Semiregular Variable R Crateris

We obtained, for the first time, astrometrically registered maps of the 22.2 GHz H2O and 42.8, 43.1, and 86.2 GHz SiO maser emission toward the semiregular b-type variable (SRb) R Crateris, at three epochs (2015 May 21, and 2016 January 7 and 26) using the Korean Very-long-baseline Interferometry Network. The SiO masers show a ring-like spatial structure, while the H2O maser shows a very asymmetric one-side outflow structure, which is located at the southern part of the ring-like SiO maser feature. We also found that the 86.2 GHz SiO maser spots are distributed in an inner region, compared to those of the 43.1 GHz SiO maser, which is different from all previously known distributions of the 86.2 GHz SiO masers in variable stars. The different distribution of the 86.2 GHz SiO maser seems to be related to the complex dynamics caused by the overtone pulsation mode of the SRb R Crateris. Furthermore, we estimated the position of the central star based on the ring fitting of the SiO masers, which is essential for interpreting the morphology and kinematics of a circumstellar envelope. The estimated stellar coordinate corresponds well to the position measured by Gaia

Asymmetric distributions of H2O and SiO masers towards V627 Cas

We performed simultaneous observations of the H2O 6(1,6) - 5(2,3) (22.235080 GHz) and SiO v= 1, 2, J = 1 - 0, SiO v = 1, J = 2 - 1, 3 - 2 (43.122080, 42.820587, 86.243442, and 129.363359 GHz) masers towards the suspected D-type symbiotic star, V627 Cas, using the Korean VLBI Network. Here, we present astrometrically registered maps of the H2O and SiO v = 1, 2, J = 1 - 0, SiO v = 1, J = 2 - 1 masers for five epochs from January 2016 to June 2018. Distributions of the SiO maser spots do not show clear ring-like structures, and those of the H2O maser are biased towards the north-north-west to west with respect to the SiO maser features according to observational epochs. These asymmetric distributions of H2O and SiO masers are discussed based on two scenarios of a bipolar outflow and the presence of the hot companion, a white dwarf, in V627 Cas. We carried out ring fitting of SiO v = 1, and v = 2 masers and estimated the expected position of the cool red giant. The ring radii of the SiO v = 1 maser are slightly larger than those of the SiO v = 2 maser, as previously known. Our assumption for the physical size of the SiO maser ring of V627 Cas to be the typical size of a SiO maser ring radius (\sim4 au) of red giants yields the distance of V627 Cas to be \sim1 kpc.Comment: 7 pages, 4 figures, 1 table, Published in MNRA

Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish

Relapse of acute lymphoblastic leukemia (ALL) is dangerous and it worsens the prognosis of patients; however, prognostic markers or therapeutic targets for ALL remain unknown. In the present study, using databases such as TARGET, GSE60926 and GSE28460, we determined that KIF2C and its binding partner, KIF18B are overexpressed in patients with relapsed ALL compared to that in patients diagnosed with ALL for the first time. As 50% of the residues are exactly the same and the signature domain of KIF2C is highly conserved between human and zebrafish, we used zebrafish embryos as a model to investigate the function of kif2c in vivo. We determined that kif2c is necessary for lymphopoiesis in zebrafish embryos. Additionally, we observed that kif2c is not related to differentiation of HSCs; however, it is important for the maintenance of HSCs as it provides survival signals to HSCs. These results imply that the ALL relapse-related gene KIF2C is linked to the survival of HSCs. In conclusion, we suggest that KIF2C can serve as a novel therapeutic target for relapsed ALL

Complexity-latency tradeoff for 5G SCL polar decoder architecture

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