Incisional hernia after ovarian debulking surgery

Objectives: The purpose of our study was to explore the incidence and contributing variables of an incisional hernia after debulking surgery for advanced ovarian cancer. Material and methods: The imaging of patients who underwent debulking surgery with an extended vertical incision was re-evaluated for incisional hernias at one-year follow-up, and their medical records were reviewed. We performed univariate and multivariate analysis to find out the risk factors for an incisional hernia. Results: The overall annual incidence of incisional hernia was 26.7 percent (46 of 172). Univariate analysis revealed a statistically significant relationship between age, body mass index (BMI), and the length of the incision and the incidence of an incisional hernia. The only factor identified by multivariate analysis as being independently related with the development of an incisional hernia within a year of the operation was BMI (OR 1.12, 95% CI 1.01–1.25, p = 0.04). Conclusions: Incisional hernia rates were high after ovarian cancer surgeries, and BMI was the independent factor significantly linked to hernia formation. To reduce the high ratio of incisional hernia among these group of patients, preventative strategies should be researched and applied

CLINICOPATHOLOGIC FEATURES OF PROBABLY MALIGNANT ADNEXAL MASSES WITHOUT SIGNS OF ASCITES AND CARCINOMATOSIS

Objective: Our objective was to assess the patients who have probable early stage ovarian cancer

Evaluation of the Results of Conservative Management of Women with Tuboovarian Abscess; Single Tertiary Center Experience

OBJECTIVE: To evaluate results of patients with conservative management of tuboovarian abscess (TOA). STUDY DESIGN: A retrospective cohort study of women with TOA. Between January 2012 and February 2015, all women that hospitalized with diagnosis of TOA enrolled in this study. Cases were analyzed with respect to age, parity, medical conditions, history of intra-uterine device use, size of TOA, C-reactive protein (CRP) levels, white blood cell (WBC) count, CA-125 levels, antibiotic usage, hospitalization period. RESULTS: Thirty-nine patients with TOA included in to this study. Mean age was 38.2 ± 11.5 years. Mean size of TOA was 5. 7 ± 2.1 cm. In comparison between patients with abscesses ≤ 6cm or >6cm, TOA size is not associated with important outcomes including duration of antibiotherapy and duration of hospitalization. CONCLUSION: Women with TOAs should be admitted to the hospital and immediately started in parenteral antibiotics. Due to high levels of success with antibiotherapy, immediate surgical management should always be performed in cases of rupture

Embryo viability indexing using Raman spectroscopy of spent culture media

Embryo viability quantification is an important topic for in vitro fertilization researchers. This study suggests Raman spectroscopy as a candidate method to find an objective measure of embryo viability. Raman spectra of 31 spent embryo culture samples (16 nonpregnant, 15 pregnant) from 31 patients were analyzed with band component analysis. The band area ratio of 902 to 943 cm 1 was found to be the most discriminatory. These bands are related to glutamine, glycine, proline, aspartic acid, and valine. According to the pregnancy outcome the sensitivity and specificity of Raman analysis were found to be 93% and 77%, respectively

Renal failure due to renal vein thrombosis in a fetus with growth restriction and thrombophilia

We report a case of renal vein thrombosis diagnosed at 27 weeks of gestation in a dichorionic twin pregnancy. The left kidney of one fetus was hyperechoic and enlarged with echoic streaks following the direction of interlobular veins and the loss of corticomedullary differentiation. In the following weeks, left kidney became smaller and echoic, and Doppler examination showed no flow in both artery and vein. The right kidney had totally normal appearance in the beginning, but it became enlarged and hyperechoic, and progressed into a small echoic kidney with no flow in artery and vein. In the postnatal ultrasound examination, both kidneys appeared hyperechoic with no vascularization in the hilum region. There was thrombosis in arteries and veins of both kidneys, as well as in the inferior vena cava. The investigation for thrombophilia resulted with the combined presence of heterozygote mutation in factor V Leiden and prothrombin 20210 genes

Spectroscopic analysis of embryo culture media for predicting reproductive potential in patients undergoing in vitro fertilization

Objective: To predict the reproductive potential of embryos via Raman spectroscopy evaluation of the spent culture media as well as with a conventional morphologic evaluation. Materials and Methods: Women of reproductive age (n=31) who were treated for unexplained infertility and scheduled for single embryo transfer were invited to participate in this prospective study. After the embryos were removed from the culture, the spent culture media were stored at -80 °C after snap-freezing in liquid nitrogen. Results: Fifteen patients were clinically pregnant, and 16 patients were clinically non-pregnant. Clinical pregnancy was predicted using Raman spectroscopy in 93% (14/15) of clinically pregnant patients, and in 62.5% (10 out of 16) of clinically non-pregnant patients. The sensitivity of the Raman spectroscopic analysis was 93% and the specificity was 62.5%. Conclusion: Metabolomic evaluation of spent embryo culture media is an emerging technique with promising objective results. However, there is clearly room for improvement