Low-rank constrained multichannel signal denoising considering channel-dependent sensitivity inspired by self-supervised learning for optical fiber sensing

Optical fiber sensing is a technology wherein audio, vibrations, and temperature are detected using an optical fiber; especially the audio/vibrations-aware sensing is called distributed acoustic sensing (DAS). In DAS, observed data, which is comprised of multichannel data, has suffered from severe noise levels because of the optical noise or the installation methods. In conventional methods for denoising DAS data, signal-processing- or deep-neural-network (DNN)-based models have been studied. The signal-processing-based methods have the interpretability, i.e., non-black box. The DNN-based methods are good at flexibility designing network architectures and objective functions, that is, priors. However, there is no balance between the interpretability and the flexibility of priors in the DAS studies. The DNN-based methods also require a large amount of training data in general. To address the problems, we propose a DNN-structure signal-processing-based denoising method in this paper. As the priors of DAS, we employ spatial knowledge; low rank and channel-dependent sensitivity using the DNN-based structure. The result of fiber-acoustic sensing shows that the proposed method outperforms the conventional methods and the robustness to the number of the spatial ranks. Moreover, the optimized parameters of the proposed method indicate the relationship with the channel sensitivity; the interpretability.Comment: Accepted for ICASSP202

The Kiloparsec-scale Neutral Atomic Carbon Outflow in the Nearby Type-2 Seyfert Galaxy NGC 1068: Evidence for Negative AGN Feedback

Active galactic nucleus (AGN) feedback is postulated as a key mechanism for regulating star formation within galaxies. Studying the physical properties of the outflowing gas from AGN is thus crucial for understanding the co-evolution of galaxies and supermassive black holes. Here we report 55 pc resolution ALMA neutral atomic carbon [CI] $^3P_1\text{-}^3P_0$ observations toward the central 1 kpc of the nearby type-2 Seyfert galaxy NGC 1068, supplemented by 55 pc resolution CO($J=1\text{-}0$) observations. We find that [CI] emission within the central kpc is strongly enhanced by a factor of $>$5 compared to the typical [CI]/CO intensity ratio of $\sim$0.2 for nearby starburst galaxies (in units of brightness temperature). The most [CI]-enhanced gas (ratio $>$ 1) exhibits a kpc-scale elongated structure centered at the AGN that matches the known biconical ionized gas outflow entraining molecular gas in the disk. A truncated, decelerating bicone model explains well the kinematics of the elongated structure, indicating that the [CI] enhancement is predominantly driven by the interaction between the ISM in the disk and the highly inclined ionized gas outflow (which is likely driven by the radio jet). Our results strongly favor the "CO dissociation scenario" rather than the "in-situ C formation" one which prefers a perfect bicone geometry. We suggest that the high [CI]/CO intensity ratio gas in NGC 1068 directly traces ISM in the disk that is currently dissociated and entrained by the jet and the outflow, i.e., the "negative" effect of the AGN feedback.Comment: 12 pages, 5 figures, accepted for publication in The Astrophysical Journal Letter

Infectious cerebral thromboembolism in a patient with lung cancer during long-term administration of gefitinib: a case report

Introduction　Gefitinib is a molecularly targeted drug for oral administration, a selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). It is effective for patients with lung cancer who have EGFR mutation and enables long-term survival of patients with advanced disease.Case presentation　An 84-year-old Asian female with lung cancer (adenocarcinoma, cT4N3M1b stage IV PUL BRA OSS ADR) was treated by gefitinib for two years. The primary tumor was markedly reduced, and bone metastasis had almost disappeared. However, the patient became unconsciousness with general edema and died two days after falling unconsciousness. In the autopsy, it was diagnosed as infectious cerebral thromboembolism due to infectious endocarditis. The cause of death was cardiac tamponade.Conclusions　While long-term survival can be expected in patients with advanced lung cancer by molecular-targeted agents, cautious management is warranted for complications, the same as for the primary disease

Poster Session: Abstracts

The 3rd International Symposium on Carcinogenic Spiral & International Symposium on Tumor Biology in Kanazawa, [DATE]: January 24(Thu)-25(Fri),2013, [Place]:Kanazawa Excel Hotel Tpkyu, Kanazawa, Japan, [Organizers]:Infection/Inflammation-Assisted Acceleration of the Carcinogenic Spiral and its Alteration through Vector Conversion of the Host Response to Tumors / Scientific Research on Innovative Areas, a MEXT Grant-in Aid Projec