Efficient Surface Peeling, a Photoinduced Result of Photochromic Diarylethene Crystal by Multistep Light Irradiation

Photomechanical materials driven by an external light stimulus have become the focus of much attention. We can operate them in a noncontact way and remotely. Photoinduced bending, one of the typical photomechanical behaviors, is often observed in elongated and thinner crystals, which makes them a promising candidate for a variety of applications. However, the preparation of crystals appropriate for bending behavior is difficult because of the complexity of their molecular structures, preparation conditions, and other factors. Here, an efficient surface peeling of crystals by multistep light irradiation using diarylethene crystals is reported. Thin crystals fabricated by this approach make up less than half the thickness of the original crystals. This shows the potential for the photocontrol of various photomechanical behaviors by the same crystal depending on the irradiation conditions

Efficient Surface Peeling, a Photoinduced Result of Photochromic Diarylethene Crystal by Multistep Light Irradiation

Photomechanical materials driven by an external light stimulus have become the focus of much attention. We can operate them in a noncontact way and remotely. Photoinduced bending, one of the typical photomechanical behaviors, is often observed in elongated and thinner crystals, which makes them a promising candidate for a variety of applications. However, the preparation of crystals appropriate for bending behavior is difficult because of the complexity of their molecular structures, preparation conditions, and other factors. Here, an efficient surface peeling of crystals by multistep light irradiation using diarylethene crystals is reported. Thin crystals fabricated by this approach make up less than half the thickness of the original crystals. This shows the potential for the photocontrol of various photomechanical behaviors by the same crystal depending on the irradiation conditions

Efficient Surface Peeling, a Photoinduced Result of Photochromic Diarylethene Crystal by Multistep Light Irradiation

Photomechanical materials driven by an external light stimulus have become the focus of much attention. We can operate them in a noncontact way and remotely. Photoinduced bending, one of the typical photomechanical behaviors, is often observed in elongated and thinner crystals, which makes them a promising candidate for a variety of applications. However, the preparation of crystals appropriate for bending behavior is difficult because of the complexity of their molecular structures, preparation conditions, and other factors. Here, an efficient surface peeling of crystals by multistep light irradiation using diarylethene crystals is reported. Thin crystals fabricated by this approach make up less than half the thickness of the original crystals. This shows the potential for the photocontrol of various photomechanical behaviors by the same crystal depending on the irradiation conditions

Efficient Surface Peeling, a Photoinduced Result of Photochromic Diarylethene Crystal by Multistep Light Irradiation

Photomechanical materials driven by an external light stimulus have become the focus of much attention. We can operate them in a noncontact way and remotely. Photoinduced bending, one of the typical photomechanical behaviors, is often observed in elongated and thinner crystals, which makes them a promising candidate for a variety of applications. However, the preparation of crystals appropriate for bending behavior is difficult because of the complexity of their molecular structures, preparation conditions, and other factors. Here, an efficient surface peeling of crystals by multistep light irradiation using diarylethene crystals is reported. Thin crystals fabricated by this approach make up less than half the thickness of the original crystals. This shows the potential for the photocontrol of various photomechanical behaviors by the same crystal depending on the irradiation conditions

Efficient Surface Peeling, a Photoinduced Result of Photochromic Diarylethene Crystal by Multistep Light Irradiation

Photomechanical materials driven by an external light stimulus have become the focus of much attention. We can operate them in a noncontact way and remotely. Photoinduced bending, one of the typical photomechanical behaviors, is often observed in elongated and thinner crystals, which makes them a promising candidate for a variety of applications. However, the preparation of crystals appropriate for bending behavior is difficult because of the complexity of their molecular structures, preparation conditions, and other factors. Here, an efficient surface peeling of crystals by multistep light irradiation using diarylethene crystals is reported. Thin crystals fabricated by this approach make up less than half the thickness of the original crystals. This shows the potential for the photocontrol of various photomechanical behaviors by the same crystal depending on the irradiation conditions

Efficient Surface Peeling, a Photoinduced Result of Photochromic Diarylethene Crystal by Multistep Light Irradiation

Photomechanical materials driven by an external light stimulus have become the focus of much attention. We can operate them in a noncontact way and remotely. Photoinduced bending, one of the typical photomechanical behaviors, is often observed in elongated and thinner crystals, which makes them a promising candidate for a variety of applications. However, the preparation of crystals appropriate for bending behavior is difficult because of the complexity of their molecular structures, preparation conditions, and other factors. Here, an efficient surface peeling of crystals by multistep light irradiation using diarylethene crystals is reported. Thin crystals fabricated by this approach make up less than half the thickness of the original crystals. This shows the potential for the photocontrol of various photomechanical behaviors by the same crystal depending on the irradiation conditions

Efficient Surface Peeling, a Photoinduced Result of Photochromic Diarylethene Crystal by Multistep Light Irradiation

Photomechanical materials driven by an external light stimulus have become the focus of much attention. We can operate them in a noncontact way and remotely. Photoinduced bending, one of the typical photomechanical behaviors, is often observed in elongated and thinner crystals, which makes them a promising candidate for a variety of applications. However, the preparation of crystals appropriate for bending behavior is difficult because of the complexity of their molecular structures, preparation conditions, and other factors. Here, an efficient surface peeling of crystals by multistep light irradiation using diarylethene crystals is reported. Thin crystals fabricated by this approach make up less than half the thickness of the original crystals. This shows the potential for the photocontrol of various photomechanical behaviors by the same crystal depending on the irradiation conditions

Efficient Surface Peeling, a Photoinduced Result of Photochromic Diarylethene Crystal by Multistep Light Irradiation

Photomechanical materials driven by an external light stimulus have become the focus of much attention. We can operate them in a noncontact way and remotely. Photoinduced bending, one of the typical photomechanical behaviors, is often observed in elongated and thinner crystals, which makes them a promising candidate for a variety of applications. However, the preparation of crystals appropriate for bending behavior is difficult because of the complexity of their molecular structures, preparation conditions, and other factors. Here, an efficient surface peeling of crystals by multistep light irradiation using diarylethene crystals is reported. Thin crystals fabricated by this approach make up less than half the thickness of the original crystals. This shows the potential for the photocontrol of various photomechanical behaviors by the same crystal depending on the irradiation conditions

Phototunable Cell Killing by Photochromic Diarylethene of Thiazoyl and Thienyl Derivatives

We report a unique phototunable cell killing technique using diarylethene molecules as photo-isomerizing-molecular switches. These molecules were delivered to DNA in the cell nucleus due to closed-form generated by UV light, and then blue light triggered cell killing. A UV light irradiation switches the open form, having no DNA intercalation activity, to the closed form to induce intercalation in DNA. This isomer, thus prepared ready for the action, exerts photocytotoxicity upon the subsequent blue light irradiation. Molecular biological analysis clarifies that photocytotoxicity is due to DNA double-strand breaks. Since cell death is observed only when irradiated with light where both the open- and closed-ring isomers have absorption, the possible mechanism of cell death is assumed to be due to the repeated photocyclization and photocycloreversion reactions of the diarylethene molecules, which induce irreparable damage to DNA. This unique photo-controllable action in a cell system can provide the basis of a novel scheme of phototherapy

Phototunable Cell Killing by Photochromic Diarylethene of Thiazoyl and Thienyl Derivatives

We report a unique phototunable cell killing technique using diarylethene molecules as photo-isomerizing-molecular switches. These molecules were delivered to DNA in the cell nucleus due to closed-form generated by UV light, and then blue light triggered cell killing. A UV light irradiation switches the open form, having no DNA intercalation activity, to the closed form to induce intercalation in DNA. This isomer, thus prepared ready for the action, exerts photocytotoxicity upon the subsequent blue light irradiation. Molecular biological analysis clarifies that photocytotoxicity is due to DNA double-strand breaks. Since cell death is observed only when irradiated with light where both the open- and closed-ring isomers have absorption, the possible mechanism of cell death is assumed to be due to the repeated photocyclization and photocycloreversion reactions of the diarylethene molecules, which induce irreparable damage to DNA. This unique photo-controllable action in a cell system can provide the basis of a novel scheme of phototherapy