Polyenylpyrrole Derivatives Inhibit NLRP3 Inflammasome Activation and Inflammatory Mediator Expression by Reducing Reactive Oxygen Species Production and Mitogen-Activated Protein Kinase Activation

10.1371/journal.pone.0076754PLoS ONE810-POLN

Generation of Reactive Oxygen Species by Polyenylpyrroles Derivatives Causes DNA Damage Leading to G2/M Arrest and Apoptosis in Human Oral Squamous Cell Carcinoma Cells

10.1371/journal.pone.0067603PLoS ONE86-POLN

ROTATIONAL ISOMERISM OF ETHANE-SUBSTITUTED COMPOUNDS

Ph.DDOCTOR OF PHILOSOPH

How COVID-19 Disrupted Our "Flipped" Freshman Organic Chemistry Course: Insights Gained from Singapore

10.1021/acs.jchemed.0c00590JOURNAL OF CHEMICAL EDUCATION9792573-258

Protecting-Group-Free Synthesis of Chondroitin 6-Sulfate Disaccharide and Tetrasaccharide

10.1021/acs.orglett.9b01457ORGANIC LETTERS21124559-456

Development of fluorous boronic acid catalysts integrated with sulfur for enhanced amidation efficiency

10.1039/d3ra03300gRSC Advances132517420-1742

CheMakers: Playing a Collaborative Board Game to Understand Organic Chemistry

10.1021/acs.jchemed.0c01116JOURNAL OF CHEMICAL EDUCATION982530-53

Fluorogenic probes to monitor cytosolic phospholipase A(2) activity

10.1039/c6cc09305aCHEMICAL COMMUNICATIONS53111813-181

Green Chemistry COMMUNICATION Development of a fluorous, oxime-based palladacycle for microwave-promoted carbon-carbon coupling reactions in aqueous media †

A thermally stable, fluorous oxime-based palladacycle has been developed and was shown to efficiently promote various carbon-carbon bond formation reactions (SuzukiMiyaura, Sonogashira and Stille) in aqueous media under microwave irradiation. The palladacycle gave extremely low levels of Pd leaching and could be reused five times with no significant loss of activity. The palladium-catalyzed carbon-carbon coupling reaction is an important tool for the synthesis of symmetric and nonsymmetric biaryls and over the decades, a wide variety of homogeneous catalytic systems have been developed for this transformation

Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility

10.1021/acsmedchemlett.0c00588ACS MEDICINAL CHEMISTRY LETTERS125704-71