6 research outputs found
Survival of Civilian and Prisoner Drug-Sensitive, Multi- and Extensive Drug- Resistant Tuberculosis Cohorts Prospectively Followed in Russia
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XDR strains molecular genotypes and proportions of common mutations associated with fluroquinolone resistance.
<p>*Clusters were identified using VNTR and spoligotyping.</p><p>**The VNTR types are given as 28-digit codes corresponding to the numbers of copies of minisatellites in respective loci (please see column heading).</p
Core common clinical and demographic characteristics of patients from the 2002-3 TB Cohort and 2008 XDRTB Cohort<sup>*</sup>.
<p>*Note: 3 people do not contribute any survival time data.</p
Uni- and multivariate Cox regression models of predictors of death.
<p>*Three people died on the same date as diagnosis and hence do not contribute any time to the analysis.</p><p>**In the multivariate Cox model age was taken as a continuous variable.</p>∧<p>Patients without available DST results from 2002-3 TB Cohort are excluded from the analysis.</p>#<p>All variables from univariate analysis significant at 10% significance level are included into multivariate analysis (2002-3 TB Cohort); multivariate analysis was not performed for 2008 XDRTB Cohort as no significant variable were identified at univariate analysis in this group.</p>$<p>In 2002-3 Cohort re-treatment cases included relapses only; in 2008 XDRTB Cohort re-treatment cases include relapses, return after default, treatment after failure, chronic patients.</p
Kaplan-Meier survival curves for patients from (A) 2002-3 TB Cohort defined by MDR- vs non-MDR status and (B) 2008 XDRTB Cohort.
<p>Kaplan-Meier survival curves for patients from (A) 2002-3 TB Cohort defined by MDR- vs non-MDR status and (B) 2008 XDRTB Cohort.</p