Spontaneous malignant myoepithelioma of the maxillary gland in a young adult male BALB/c F1 hybrid mouse

如何合理架构我国教育大数据的发展路向，切实推进大数据驱动的教育教学变革与优化，是当前我国教育领域面临的重大挑战。州级纵向数据系统是美国应用大数据优化教育教学的重要抓手，其建设与发展实则为美国教育大数据实践的核心脉络。本研究从立法保障、项目支持、标准引领和机构推进四个方面，系统探究美国州级纵向数据系统的建设与发展特征，并进一步结合我国发展实际，总结出对我国教育大数据发展的建设基础以及联动、安全与深度应用等方面的重要启示，以期为我国教育大数据发展提供有益参考与借鉴。广西民族大学相思湖青年学者（教育精准扶贫）创新团

Gastrointestinal Obstruction due to Solitary Lymph Node Recurrence of Alpha-Fetoprotein-Producing Gastric Carcinoma with Enteroblastic Differentiation

We report an unusual case of alpha-fetoprotein (AFP)-producing gastric carcinoma with enteroblastic differentiation. A 75-year-old woman was admitted to our hospital with occasional upper abdominal discomfort. We performed gastroscopy and observed a type 2 tumor, primarily in the pyloric region. Histological examination of biopsies confirmed gastric adenocarcinoma. Based on these findings, we diagnosed gastric adenocarcinoma and performed laparoscopic distal gastrectomy with lymph node dissection. Histological examination revealed an invasive lesion composed of adenocarcinoma with a tubulopapillary growth pattern. Tumor cells were cuboidal in shape with characteristically clear cytoplasm rich in glycogen. Two regional lymph node metastases were seen microscopically. Immunohistochemically these cells were positive for AFP, carcinoembryonic antigen, caudal-type homeobox transcription factor 2 and common acute lymphoblastic leukemia antigen. The final diagnosis was AFP-producing gastric carcinoma with enteroblastic differentiation. 26 months after initial surgery, the patient was readmitted to our hospital for gastrointestinal obstruction due to lymph node recurrence