The Source Detection of 28 September 2018 Sulawesi Tsunami by Using Ionospheric GNSS Total Electron Content Disturbance

The 28 September 2018 magnitude Mw7.8 Palu, Indonesia earthquake (0.178° S, 119.840° E, depth 13 km) occurred at 10:02 UTC. The major earthquake triggered catastrophic liquefaction, landslides, and a near-field tsunami. The ionospheric total electron content (TEC) derived from records of 5 ground-based global navigation satellite system (GNSS) receivers is employed to detect tsunami traveling ionospheric disturbances (TTIDs). In total, 15 TTIDs have been detected. The ray-tracing and beamforming techniques are then used to find the TTID source location. The bootstrap method is applied in order to further explore the possible location of the tsunami source based on results of the two techniques, which show the beamforming technique has a slightly better performance on finding possible locations of the tsunami source. Meanwhile, the circle method is employed to examine tsunami signatures of the sea-surface height and video records, and find possible tsunami origin locations. The coincidence of the TTID source location and the tsunami location shows that the ionospheric TEC recorded by local ground-based GNSS receivers can be used to confirm the tsunami occurrence, find the tsunami location, and support the tsunami early warning

Genome-Wide Association Study of Lung Adenocarcinoma in East Asia and Comparison With a European Population

Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study of lung adenocarcinoma of East Asian ancestry (21,658 cases and 150,676 controls; 54.5% never-smokers) and identified 12 novel susceptibility variants, bringing the total number to 28 at 25 independent loci. Transcriptome-wide association analyses together with colocalization studies using a Taiwanese lung expression quantitative trait loci dataset (n = 115) identified novel candidate genes, including FADS1 at 11q12 and ELF5 at 11p13. In a multi-ancestry meta-analysis of East Asian and European studies, four loci were identified at 2p11, 4q32, 16q23, and 18q12. At the same time, most of our findings in East Asian populations showed no evidence of association in European populations. In our studies drawn from East Asian populations, a polygenic risk score based on the 25 loci had a stronger association in never-smokers vs. individuals with a history of smoking (Pinteraction = 0.0058). These findings provide new insights into the etiology of lung adenocarcinoma in individuals from East Asian populations, which could be important in developing translational applications

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study of lung adenocarcinoma of East Asian ancestry (21,658 cases and 150,676 controls; 54.5% never-smokers) and identified 12 novel susceptibility variants, bringing the total number to 28 at 25 independent loci. Transcriptome-wide association analyses together with colocalization studies using a Taiwanese lung expression quantitative trait loci dataset (n = 115) identified novel candidate genes, including FADS1 at 11q12 and ELF5 at 11p13. In a multi-ancestry meta-analysis of East Asian and European studies, four loci were identified at 2p11, 4q32, 16q23, and 18q12. At the same time, most of our findings in East Asian populations showed no evidence of association in European populations. In our studies drawn from East Asian populations, a polygenic risk score based on the 25 loci had a stronger association in never-smokers vs. individuals with a history of smoking (P interaction  = 0.0058). These findings provide new insights into the etiology of lung adenocarcinoma in individuals from East Asian populations, which could be important in developing translational applications

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population.

Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study of lung adenocarcinoma of East Asian ancestry (21,658 cases and 150,676 controls; 54.5% never-smokers) and identified 12 novel susceptibility variants, bringing the total number to 28 at 25 independent loci. Transcriptome-wide association analyses together with colocalization studies using a Taiwanese lung expression quantitative trait loci dataset (n = 115) identified novel candidate genes, including FADS1 at 11q12 and ELF5 at 11p13. In a multi-ancestry meta-analysis of East Asian and European studies, four loci were identified at 2p11, 4q32, 16q23, and 18q12. At the same time, most of our findings in East Asian populations showed no evidence of association in European populations. In our studies drawn from East Asian populations, a polygenic risk score based on the 25 loci had a stronger association in never-smokers vs. individuals with a history of smoking (Pinteraction = 0.0058). These findings provide new insights into the etiology of lung adenocarcinoma in individuals from East Asian populations, which could be important in developing translational applications

Banyan-based Architecture for Quasi-Circuit Switching

[[abstract]]Load balanced Birkoff-von Neumann quasi-circuit switching was proposed to control the packet delay, as well as to solve the head-of-line blocking problem. Quasi-circuit switching, a frame based scheme, is proposed to provide guaranteed rate services. However, as the switch dimension increases, the maximum delay and the size of the one-cycle permutation matrices increase accordingly. In this work, a new architecture - Banyan-based quasi-circuit switching is proposed. A large dimension switch is decomposed into multiple 2times2 frame-based switching elements in order to reduce the implementation complexity. According to the numerical and simulation results, it was found that the performance of the Banyan-based architecture is better than that of the load-balanced architecture. Especially, the standard deviation of the average packet delay can be greatly reduced by applying the proposed architecture. Therefore, the overall packet delay in a network can be well controlled and predicted[[fileno]]2030151030013[[department]]電機工程學

M-ary Spreading-Code-Phase-Shift-Keying Modulation for DSSS Multiple Access Systems

[[abstract]]Code shift keying (CSK) was proposed to increase the transmission efficiency of DSSS systems, and to overcome the spreading gain versus data rate limitation. However, CSK modulation provides no multi-access capability, and degrades the flexibility of a spread spectrum system. In this work, a generalized M-ary DSSS modulation scheme, spreading code phase shift keying (SCPSK), is proposed to improve the system flexibility, and to provide the multi-access capability. This scheme involves switching the spreading code phase in accordance with the incoming data. The union bound of the symbol error probability, in an AWGN channel exposed to multi-user interference, are derived for performance evaluation. Furthermore, the performance of M-SCPSK in a multipath fading channel is investigated via simulation and compared with the conventional DSSS-BPSK scheme.[[fileno]]2030151010021[[department]]電機工程學

Sensing Coverage for Randomly Distributed Wireless Sensor Networks in Shadowed Environments

[[abstract]]Sensing Coverage for Randomly Distributed Wireless Sensor Networks in Shadowed Environments[[fileno]]2030151010014[[department]]電機工程學

A new MAC protocol for streaming services in wireless multi-channel mobile ad hoc networks

[[abstract]]In single-channel MANETs, a heavy traffic load will degrade system performance, making streaming services inapplicable. Hence, several multi-channel MAC protocols for MANETs have been proposed and investigated. In this work, we propose a dedicated channel for streaming services (DCSS) scheme for streaming services in multi-channel MANETs. A new dedicated channel is assigned for heavy traffic or streaming services. In addition, system performance and the impact of the DCSS scheme on non-streaming services are thoroughly investigated. According to the simulation results, the DCSS scheme was found to greatly improve the performance of the network, including streaming and non-streaming services. The impact of the DCSS scheme on non-streaming services is also acceptable. The increase in average number of hops is limited to 10%; the loss of network connectivity is negligible in the cases with high node density.[[fileno]]2030151030011[[department]]電機工程學

Valid Cell Coverage and Maximum Available Data Rate for Third Generation CDMA Mobile Communication Systems

[[fileno]]2030151030044[[department]]電機工程學