Measurement and prediction of water coverage of blade ring in a turbocharger

See published paper</p

Comparison study of turbine blade with trailing–edge cutback coolant ejection designs

This paper investigates a turbine blade with two trailing-edge cutback coolant ejection designs, aiming for a comparison study of aerothermal performances such as discharge coefficient and film cooling effectiveness due to trailing-edge geometry change.</p

Evaluation of wall heat transfer in turbine blade trailing-edge passage

to be completed later</p

Effect of hole shape on blade cooling effectiveness

See paper published</p

Modelling air and water two-phase annular flow in small horizontal pipe

Numerical study using Computational Fluid Dynamics (CFD) has been carried out to investigate flow behaviours and underlying physical phenomena associated with air/water two-phase flow inside a small horizontal tube of an inner diameter 8.8mm. The base liquid film thickness distributions, determined by either wavy or full annular flow regime, are compared with available experimental data. CFD simulation has successfully predicted the wavy structure applying a user defined function, which has coupled in ANSYS-FLUENT solver to correlate with other two-phase flow models under the Eulerian–Eulerian framework. Results from liquid distributions and two-phase flow behaviours have indicated the presence of strong gas/liquid interferences. This can largely contribute towards the thickening of the liquid film coverage along the top pipe wall surface for a fully developed annular flow, compared to those occurred in the wavy annular flow regime. This is due to possible earlier droplets broken down thus the liquid wavy front can travel from the low part of the pipe to the upper wall surface. Some discrepancies between CFD prediction and experimental data could be due to the limitation of CFD model as only a simplified 2D variant is adopted, rather than a full 3D transient two-phase flow model.</p

Clinical characteristics of the subjects enrolled in the present study (Data are mean±SD).

<p>Clinical characteristics of the subjects enrolled in the present study (Data are mean±SD).</p

The Association of Adiponectin Gene Promoter Variations with Non-Small Cell Lung Cancer in a Han Chinese Population

<div><p>Recently, in vitro studies have demonstrated that adiponectin has antiangiogenic and tumor growth-limiting properties. Additionally, serum adiponectin levels have been associated with the risk of several cancers; specifically, serum adiponectin was significantly lower in lung cancer patients with advanced-stage disease. In this study, we examined the association of adiponectin gene promoter variations associated with adiponectin gene expression and plasma levels in non-small cell lung cancer (NSCLC) in a Han Chinese population. A total of 319 patients with NSCLC and 489 healthy individuals were recruited to evaluate the association of four adiponectin gene promoter single-nucleotide polymorphisms (SNPs) (SNP-12140G>A, SNP-11426A>G, SNP-11391G>A and SNP-11377C>G) with NSCLS risk. Additionally, we constructed haplotypes of these four SNPs and evaluated the association of these haplotypes with NSCLS risk. Our results showed that among these four SNPs, only SNP-12140G>A was associated with NSCLC risk(P<0.05). The haplotype analysis showed that no haplotype was associated with NSCLC after performing a Bonferroni correction (P>0.05). Additionally, an association analysis of the four SNPs stratified into pathologic stages I+II and III+IV showed that these SNPs did not exhibit significant differences between pathologic stages I+II and III+IV. Moreover, we did not observe any differences in allele and genotype frequency for these SNPs between adenocarcinoma and squamous cell carcinoma. Our results indicated that the G allele of SNP-12140may be a risk factor for NSCLC (OR = 1.516; 95% CI: 1.098–2.094) in this Han Chinese population.</p></div

Different inheritance models analysis of the SNP-11377C>G in adiponectin gene promoter between NSCLC and control groups.

<p>Different inheritance models analysis of the SNP-11377C>G in adiponectin gene promoter between NSCLC and control groups.</p

Comparison of genotypic and allelic distribution of SNP-12140G>A, SNP-11426A>G, SNP-11377C>G between pathologic stages I+II and III+IV.

<p>Comparison of genotypic and allelic distribution of SNP-12140G>A, SNP-11426A>G, SNP-11377C>G between pathologic stages I+II and III+IV.</p

Different inheritance models analysis of the SNP-11426A>G in adiponectin gene promoter between NSCLC and control groups.

<p>Different inheritance models analysis of the SNP-11426A>G in adiponectin gene promoter between NSCLC and control groups.</p