Visible Light-Activatable Oxidase Mimic of 9‑Mesityl-10-Methylacridinium Ion for Colorimetric Detection of Biothiols and Logic Operations

In this work, 9-mesityl-10-methylacridinium ion (Acr⁺-Mes) is found to act as an effective photocatalyst mimicking the function of oxidase. Upon visible light illumination, the excited Acr⁺-Mes is able to exhibit superior enzymatic catalytic activity for small molecular substrates as well as protein biomacromolecule (cytochrome c). The experiment results demonstrate that the Acr⁺-Mes oxidase mimic shows higher affinity to 3,3′,5,5′-tetramethylbenzidine (TMB) than natural horseradish peroxidase or the reported molecule oxidase mimic. The reaction mechanism is ascribed to the strong oxidation property of the long-lived electron-transfer state (Acr^•-Mes^•+) and the electron transfer from Acr^•-Mes radical to dissolved oxygen to generate superoxide radicals, which can easily oxidize various substrates. On the basis of these observations, the light-activatable Acr⁺-Mes with an oxidase-like activity as the probe is utilized for cost-effective, sensitive, and highly selective colorimetric detection of two biothiols (L-cysteine and L-glutathione). The lowest detectable concentrations of L-Cys and L-GSH is 100 nM, which is lower than that of most of the reported methods for biothiols. Beyond this, we construct a series of visual molecular logic gates (AND, INH, and NOR) using the oxidase mimic-involved reaction systems

Versatile Visual Logic Operations Based on Plasmonic Switching in Label-Free Molybdenum Oxide Nanomaterials

Despite some visual colorimetric chemical logic gates having been reported, a complete set of six basic logic gates have not been realized to date. Moreover, the application of the reported logic gates needs to be further extended. Herein, the label-free molybdenum oxide nanomaterials are presented for the construction of a new visual colorimetric molecular computing system. A complete set of six basic colorimetric logic gates (OR, AND, NOR, NAND, XOR, XNOR) and the INH logic gate are realized based on plasmonic switching in MoO₃ nanomaterials. In addition, the rational integration of different logic gates into a 1:2 demultiplexer circuit is also testified

Versatile Visual Logic Operations Based on Plasmonic Switching in Label-Free Molybdenum Oxide Nanomaterials

Despite some visual colorimetric chemical logic gates having been reported, a complete set of six basic logic gates have not been realized to date. Moreover, the application of the reported logic gates needs to be further extended. Herein, the label-free molybdenum oxide nanomaterials are presented for the construction of a new visual colorimetric molecular computing system. A complete set of six basic colorimetric logic gates (OR, AND, NOR, NAND, XOR, XNOR) and the INH logic gate are realized based on plasmonic switching in MoO₃ nanomaterials. In addition, the rational integration of different logic gates into a 1:2 demultiplexer circuit is also testified