5,336 research outputs found
Angiogenesis and Vasculogenesis at 7-Day of Reperfused Acute Myocardial Infarction
Objectives 
This study is to investigate the angiogenesis and vasculogenesis at the first week of reperfused acute myocardial infarction (AMI).
Methods 
16 of mini-swines (20 to 30 Kg) were randomly assigned to the sham-operated group and the AMI group. The acute myocardial infarction and reperfusion model was created and the pig tail catheter was performed to monitor hemodynamics before left anterior descending coronary artery (LAD) occlusion, 90 min of LAD occlusion and 120 min of LAD reperfusion. Pathologic myocardial tissue was collected at 7-day of LAD reperfusion and further assessed by immunochemistry, dual immunochemistry, in-situ hybridization, real-time quantitative polymerase chain reaction and western blot. 
Results 
The infarcted area had higher FLK1 mRNA expression than sham-operated area and the normal area (all P<0.05), and the infarcted and marginal areas showed higher CD146 protein expression than the sham-operated area (all P<0.05), but the microvessel density (CD31 positive expression of microvessels/HP) was not significantly different between the infarcted area and the sham-operated area (8.92±3.05 vs 6.43±1.54) at 7-day of reperfused acute myocardial infarction (P>0.05). 
Conclusions 
FLK1 and CD146 expression significantly increase in the infarcted and marginal areas, and the microvessel density is not significantly different between the infarcted area and the sham-operated area, suggesting that angiogenesis and vasculogenesis in the infarcted area appear to high frequency of increase in 7-day of reperfused myocardial infarction. 

Slave particle approach to the finite temperature properties of ultracold Bose gases in optical lattices
By using slave particle (slave boson and slave fermion) technique on the
Bose-Hubbard model, we study the finite temperature properties of ultracold
Bose gases in optical lattices. The phase diagrams at finite temperature are
depicted by including different types of slave particles and the effect of the
finite types of slave particles is estimated. The superfluid density is
evaluated using the Landau second order phase transition theory. The atom
density, excitation spectrum and dispersion curve are also computed at various
temperatures, and how the Mott-insulator evolves as the temperature increases
is demonstrated. For most quantities to be calculated, we find that there are
no qualitatively differences in using the slave boson or the slave fermion
approaches. However, when studying the stability of the mean field state, we
find that in contrast to the slave fermion approach, the slave boson mean field
state is not stable. Although the slave boson mean field theory gives a
qualitatively correct phase boundary, it corresponds to a local maximum of
Landau free energy and can not describe the second order phase transition
because the coefficient of the fourth order term is always negative in
the free energy expansion.Comment: 27 pages, 8 figures, final version for publicatio
Single top or bottom production associated with a scalar in \gamma p collision as a probe of topcolor-assisted technicolor
In the framework of the topcolor-assisted technicolor (TC2) models, we study
the productions of a single top or bottom quark associated with a scalar in
\gamma-p collision, which proceed via the subprocesses c\gamma -> t\pi_t^0,
c\gamma -> t h_t^0 and c\gamma -> b\pi^+_t mediated by the anomalous top or
bottom coupling tc\pi_t^0, tch_t^0 and bc\pi_t^+. These productions, while
extremely suppressed in the Standard Model, are found to be significantly
enhanced in the large part of the TC2 parameter space, especially the
production via c\gamma -> b\pi^+ can have a cross section of 100 fb, which may
be accessible and allow for a test of the TC2 models.Comment: 13 pages, 4 figures, comments and references adde
An Analytical Approach to the Protein Designability Problem
We present an analytical method for determining the designability of protein
structures. We apply our method to the case of two-dimensional lattice
structures, and give a systematic solution for the spectrum of any structure.
Using this spectrum, the designability of a structure can be estimated. We
outline a heirarchy of structures, from most to least designable, and show that
this heirarchy depends on the potential that is used.Comment: 16 pages 4 figure
Production of mirror fermions via and collisions in the littlest Higgs model with T-parity
One of the important features of the littlest Higgs model with T-parity,
called the model, is that it introduces the mirror fermions, which are
the T-parity partners of the standard model fermions. In this paper, we discuss
production of the mirror quark associated with mirror neutrino via
and collisions. We find that, in wide range of the parameter space, the
mirror quark can be copiously produced at the International Linear
Collider and collider experiments. The production rates
of certain signal events, which are related the main two-body decay modes of
the mirror quark, are also calculated.Comment: 19 pages, 11 figure
ACBD3 functions as a scaffold to organize the Golgi stacking proteins and a Rab33b-GAP
Golgin45 plays important roles in Golgi stack assembly and is known to bind both the Golgi stacking protein GRASP55 and Rab2 in the medial‐Golgi cisternae. In this study, we sought to further characterize the cisternal adhesion complex using a proteomics approach. We report here that Acyl‐CoA binding domain containing 3 (ACBD3) is likely to be a novel binding partner of Golgin45. ACBD3 interacts with Golgin45 via its GOLD domain, while its co‐expression significantly increases Golgin45 targeting to the Golgi. Furthermore, ACBD3 recruits TBC1D22, a Rab33b GTPase activating protein (GAP), to a large multi‐protein complex containing Golgin45 and GRASP55. These results suggest that ACBD3 may provide a scaffolding to organize the Golgi stacking proteins and a Rab33b‐GAP at the medial‐Golgi
Vacancy-induced resistive switching and synaptic behavior in flexible BST@C-f memristor crossbars
Effects of the littlest Higgs model with T-parity on Higgs boson production at high energy colliders
The Higgs boson production processes , , and
are very important for studying Higgs boson
properties and further testing new physics beyond the standard model() in
the high energy linear
collider(). We estimate the contributions of the littlest
Higgs model with T-parity( model) to these processes and find that the
model can generate significantly corrections to the production cross
sections of these processes.
We expect the possible signals of the model can be detected via these
processes in the future experiments.Comment: 9 pages, 2 figures, references adde
Lepton flavor violation decays in the topcolor-assisted technicolor model and the littlest Higgs model with parity
The new particles predicted by the topcolor-assisted technicolor ()
model and the littlest Higgs model with T-parity (called model) can
induce the lepton flavor violation () couplings at tree level or one loop
level, which might generate large contributions to some processes. Taking
into account the constraints of the experimental data on the relevant free
parameters, we calculate the branching ratios of the decay processes
with = , and
in the context of these two kinds of new physics models. We find
that the model and the model can indeed produce significant
contributions to some of these decay processes.Comment: 24 pages, 7 figure
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