120 research outputs found

    Additional file 1 of Dietary factors and Alzheimer’s disease risk: a Mendelian randomization study

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    Additional file 1: Table S1. Summary of 20 dietary habits questionnaire. Table S2. Results for Mendelian randomization analyses (IVW). Figure S1. Scatterplot analysis for dietary habits and AD. Figure s2. MR leave-one-out analysis for dietary habits and AD. Figure S3. Funnel plots of the association between dietary habits and AD

    Comparison of distance distribution between networks simulated by the evolution model and brain networks derived from experimental fMRI data from the patient group of 5 subjects.

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    <p>The distance distribution of the overall connections in the brain networks of the control group (blue line) and the patient group (red line) are shown in the graph. The dashed green line shows the distance distribution of the overall connections in networks simulated by the evolution model. The dashed purple line shows the distance distribution of the simulated networks evolved by a second independent dataset.</p

    Mean values of the small worldness (A) estimated from the experimental fMRI data and the simulated networks.

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    <p>Rectangular boxes indicate the standard deviations and dots indicate the mean values. Asterisks denote significant (Wilcoxon rank test, ) difference between conditions. The same applies for rectangular boxes, dots and asterisks in panel B. Mean values of the number of long-distance connection (B) estimated from the experimental fMRI data and the simulated networks.</p

    Illustration of lesion location in red for each patient.

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    <p>Illustration of lesion location in red for each patient.</p

    Paradigm design.

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    <p>Paradigm design.</p

    Clinical and demographic data.

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    <p>Clinical and demographic data.</p

    Scatter plots of the small worldness and the number of long-distance connections.

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    <p>X-axis denotes the small worldness; Y-axis denotes the number of long-distance connections (). All the values are grouped by control group or patient group while the green triangles represent the distribution of all simulated networks. The purple triangles represent the simulated networks evolved by a second independent dataset. All patients are labeled in line with the patient numbers in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0082845#pone-0082845-t001" target="_blank">Table 1</a>.</p

    The small worldness (A) and the number of long-distance connections () (B) of brain networks in the control group and the patient group.

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    <p>Vertical lines denote the standard deviation of each group. Asterisks denote significant differences (Wilcoxon rank test, ) between two groups at corresponding network densities.</p

    Comparison of the connection distance between controls and patients.

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    <p>The distance of connections in brain networks of control group (blue) and patient group (red) were shown.</p
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