Relativistic effects on the observed AGN luminosity distribution

Recently Zhang (2005) has proposed a model to account for the well established effect that the fraction of type-II AGNs is anti-correlated with the observed X-ray luminosity; the model consists of an X-ray emitting accretion disk coaligned to the dusty torus within the standard AGN unification model. In this paper the model is refined by including relativistic effects of the observed X-ray radiations from the vicinity of the supermassive black hole in an AGN. The relativistic corrections improve the combined fitting results of the observed luminosity distribution and the type-II AGN fraction, though the improvement is not significant. The type-II AGN fraction prefers non- or mildly spinning black hole cases and rules out the extremely spinning case.Comment: 9 pages, 4 figures, accepted for publication in PAS

A nontrivial solution for a nonautonomous Choquard equation with general nonlinearity

With the help of the monotonicity trick, a nonautonomous Choquard equations with general nonlinearity is studied and a nontrivial solution is obtained

Security of Deputy Signature

E-system, a new commerce model, is a new era for business direction. When a principal is absent (goes on an errand or on leave), a well-designed deputy system keeps the business operations working. In the network world, identity verification and any substitute for traditional signature can be done by digital signature [1]. Deputy signature guarantees the existence of deputy system in e-system. Current deputy mechanism addresses the verification of deputy signature. No research has been done on the prevention of the illegal use of deputy system when the principal returns and the deputy system is not in use. We propose a mechanism to solve the problem of illegal use of deputy system when the power of deputy system is not legally “ON.

Assessing the safety and efficacy of switching to brinzolamide/timolol fixed combination as a replacement therapy in patients with uncontrolled intraocular pressure in Taiwan

AbstractPurposeThe objective of this study is to assess the safety and efficacy of switching to brinzolamide 1% and timolol 0.5% fixed combination (BTFC) from prior pharmacotherapy in patients with open-angle glaucoma (OAG) or ocular hypertension (OH) in Taiwan.MethodsThis was a multicenter, open-labeled, interventional prospective study. The 8-week study involved patients with OAG or OH with uncontrolled intraocular pressure (IOP) and consisted of three study visits to the clinical site. Patients were instructed to discontinue their prior medications at the first visit, prior to starting the study medication. Enrolled patients were dosed with BTFC twice daily in both eyes for 8 weeks. IOP measurements and safety evaluations were conducted at both Week 4 and Week 8.ResultsA total of 74 patients were enrolled. The overall mean IOP reductions from baseline after Week 8 of BTFC was 3.45 mmHg (15.42%); when subgrouped by prior medication class (β-blockers vs. non-β-blockers), the reduction in mean IOP after transitioning to BTFC at Week 8 was as follows: subgroup β-blockers were 3.23 mmHg (14.9 %) and non-β-blockers were 3.58 mmHg (15.25%). All mean IOP changes from baseline were statistically significant (p < 0.001). Of the 69 patients (per protocol population) who were switched to BTFC regardless of prior therapy, 37 (53.6%) patients at Week 4 and 38 (55.1%) patients at Week 8 had IOP ≤ 18 mmHg. No treatment-related serious adverse events were reported in this study.ConclusionThe results of this study demonstrated the potential benefit of using BTFC as a replacement therapy in order to ensure adequate IOP control. BTFC administered twice daily was safe and effective in patients with uncontrolled IOP in Taiwan

Accelerating Split Federated Learning over Wireless Communication Networks

The development of artificial intelligence (AI) provides opportunities for the promotion of deep neural network (DNN)-based applications. However, the large amount of parameters and computational complexity of DNN makes it difficult to deploy it on edge devices which are resource-constrained. An efficient method to address this challenge is model partition/splitting, in which DNN is divided into two parts which are deployed on device and server respectively for co-training or co-inference. In this paper, we consider a split federated learning (SFL) framework that combines the parallel model training mechanism of federated learning (FL) and the model splitting structure of split learning (SL). We consider a practical scenario of heterogeneous devices with individual split points of DNN. We formulate a joint problem of split point selection and bandwidth allocation to minimize the system latency. By using alternating optimization, we decompose the problem into two sub-problems and solve them optimally. Experiment results demonstrate the superiority of our work in latency reduction and accuracy improvement

Novel Microfiber Sensor and Its Biosensing Application for Detection of hCG Based on a Singlemode-Tapered Hollow Core-Singlemode Fiber Structure

A novel microfiber sensor is proposed and demonstrated based on a singlemode-tapered hollow core -singlemode (STHS) fiber structure. Experimentally a STHS with taper waist diameter of 26.5 μm has been fabricated and RI sensitivity of 816, 1601.86, and 4775.5 nm/RIU has been achieved with RI ranges from 1.3335 to 1.3395 , from 1.369 to 1.378, and from 1.409 to 1.4175 respectively, which agrees very well with simulated RI sensitivity of 885, 1517, and 4540 nm/RIU at RI ranges from 1.3335 to 1.337, from 1.37 to 1.374, and from 1.41 to 1.414 . The taper waist diameter has impact on both temperature and strain sensitivity of the sensor structure: (1) the smaller the waist diameter, the higher the temperature sensitivity, and experimentally 26.82 pm/°C has been achieved with a taper waist diameter of 21.4 μm; (2) as waist diameter decrease, strain sensitivity increase and 7.62 pm/με has been achieved with a taper diameter of 20.3 μm. The developed sensor was then functionalized for human chorionic gonadotropin (hCG) detection as an example for biosensing application. Experimentally for hCG concentration of 5 mIU/ml, the sensor has 0.5 nm wavelength shift, equivalent to limit of detection (LOD) of 0.6 mIU/ml by defining 3 times of the wavelength variation (0.06 nm) as measurement limit. The biosensor demonstrated relatively good reproducibility and specificity, which has potential for real medical diagnostics and other applications