1,791 research outputs found
A Tale of Four Functions and Their Relationships with the Device: Extending Implementation Intention Theory
10.1109/TPC.2011.2182570IEEE Transactions on Professional Communication55136-5
GeneAlign: a coding exon prediction tool based on phylogenetical comparisons
GeneAlign is a coding exon prediction tool for predicting protein coding genes by measuring the homologies between a sequence of a genome and related sequences, which have been annotated, of other genomes. Identifying protein coding genes is one of most important tasks in newly sequenced genomes. With increasing numbers of gene annotations verified by experiments, it is feasible to identify genes in the newly sequenced genomes by comparing to annotated genes of phylogenetically close organisms. GeneAlign applies CORAL, a heuristic linear time alignment tool, to determine if regions flanked by the candidate signals (initiation codon-GT, AG-GT and AG-STOP codon) are similar to annotated coding exons. Employing the conservation of gene structures and sequence homologies between protein coding regions increases the prediction accuracy. GeneAlign was tested on Projector dataset of 491 human–mouse homologous sequence pairs. At the gene level, both the average sensitivity and the average specificity of GeneAlign are 81%, and they are larger than 96% at the exon level. The rates of missing exons and wrong exons are smaller than 1%. GeneAlign is a free tool available at
Novel computational technologies for next-generation sequencing data analysis and their applications
The Interplay of Reovirus with Autophagy
Autophagy participates in multiple fundamental physiological processes, including survival, differentiation, development, and cellular homeostasis. It eliminates cytoplasmic protein aggregates and damaged organelles by triggering a series of events: sequestering the protein substrates into double-membrane vesicles, fusing the vesicles with lysosomes, and then degrading the autophagic contents. This degradation pathway is also involved in various disorders, for instance, cancers and infectious diseases. This paper provides an overview of modulation of autophagy in the course of reovirus infection and also the interplay of autophagy and reovirus
Classifying TIM Barrel Protein Domain Structure by an Alignment Approach Using Best Hit Strategy and PSI-BLAST
Semi-Supervised Video Salient Object Detection Using Pseudo-Labels
Deep learning-based video salient object detection has recently achieved
great success with its performance significantly outperforming any other
unsupervised methods. However, existing data-driven approaches heavily rely on
a large quantity of pixel-wise annotated video frames to deliver such promising
results. In this paper, we address the semi-supervised video salient object
detection task using pseudo-labels. Specifically, we present an effective video
saliency detector that consists of a spatial refinement network and a
spatiotemporal module. Based on the same refinement network and motion
information in terms of optical flow, we further propose a novel method for
generating pixel-level pseudo-labels from sparsely annotated frames. By
utilizing the generated pseudo-labels together with a part of manual
annotations, our video saliency detector learns spatial and temporal cues for
both contrast inference and coherence enhancement, thus producing accurate
saliency maps. Experimental results demonstrate that our proposed
semi-supervised method even greatly outperforms all the state-of-the-art fully
supervised methods across three public benchmarks of VOS, DAVIS, and FBMS.Comment: ICCV2019, code is available at
https://github.com/Kinpzz/RCRNet-Pytorc
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