Stormwater Quality Characteristics and Reuse Analysis of Different Underlying Surfaces at Wanzhou North Station

In response to the water shortage in Wanzhou North Station (WNS), the authors investigated the stormwater quality characteristics with different underlying surfaces of WNS and carried out stormwater reuse analysis in conjunction with the InfoWorks ICM model. The results show that during heavy, torrential, and moderate rainfall, the road stormwater runoff has the highest concentrations of pollutants, with an average EMC (event mean concentration) value of 206 mg/L for COD. For the square runoff, the average EMC values of COD, SS, TN, and TP are 108 mg/L, 395 mg/L, 2.113 mg/L, and 0.128 mg/L, in comparison, the average EMC values of the corresponding indexes for the roof runoff are 65 mg/L, 212 mg/L, 1.449 mg/L, and 0.086 mg/L, respectively, demonstrating their potential for reuse. The R2 (coefficient of determination) of SS and COD in both roof and square runoff are greater than 0.85, with a good correlation, indicating that SS removal is the key to stormwater purification. InfoWorks ICM analysis shows that the recyclable volume of rainwater from WNS in 2018 is 29,410 m3 , accounting for 61.8% of the total annual rainfall. This study is expected to provide an ideal reference for the stormwater management of public buildings in mountainous areas

The conservation and uniqueness of the caspase family in the basal chordate, amphioxus

<p>Abstract</p> <p>Background</p> <p>The caspase family, which plays a central role in apoptosis in metazoans, has undergone an expansion in amphioxus, increasing to 45 members through domain recombination and shuffling.</p> <p>Results</p> <p>In order to shed light on the conservation and uniqueness of this family in amphioxus, we cloned three representative caspase genes, designated as <it>bbtCaspase-8, bbtCaspase-1/2 </it>and <it>bbtCaspase3</it>-like, from the amphioxus <it>Branchiostoma belcheri tsingtauense</it>. We found that <it>bbtCaspase-8 </it>with conserved protein architecture is involved in the Fas-associated death domain-Caspase-8 mediated pro-apoptotic extrinsic pathway, while <it>bbtCaspase3</it>-like may mediate a nuclear apoptotic pathway in amphioxus. Also, <it>bbtCaspase-1/2 </it>can co-localize with <it>bbtFADD2 </it>in the nucleus, and be recruited to the cytoplasm by amphioxus apoptosis associated speck-like proteins containing a caspase recruitment domain, indicating that <it>bbtCaspase-1/2 </it>may serve as a switch between apoptosis and caspase-dependent innate immune response in invertebrates. Finally, amphioxus extrinsic apoptotic pathway related caspases played important roles in early embryogenesis.</p> <p>Conclusions</p> <p>Our study not only demonstrates the conservation of <it>bbtCaspase-8 </it>in apoptosis, but also reveals the unique features of several amphioxus caspases with novel domain architectures arose some 500 million years ago.</p

Canonical Correlation Study on the Relationship between Shipping Development and Water Environment of the Yangtze River

The sustainable development of the Yangtze River will affect the lives of the people who live along it as well as the development of cities beside it. This study investigated the relationship between shipping development and the water environment of the Yangtze River. Canonical correlation analysis is a multivariate statistical method used to study the correlation between two groups of variables; this study employed it to analyze data relevant to shipping and the water environment of the Yangtze River from 2006 to 2016. Furthermore, the Yangtze River Shipping Prosperity Index and Yangtze River mainline freight volume were used to characterize the development of Yangtze River shipping. The water environment of the Yangtze River is characterized by wastewater discharge, ammonia nitrogen concentration, biochemical oxygen demand, the potassium permanganate index, and petroleum pollution. The results showed that a significant correlation exists between Yangtze River shipping and the river&rsquo;s water environment. Furthermore, mainline freight volume has a significant impact on the quantity of wastewater discharged and petroleum pollution in the water environment

An Empirical Comparison of Discrete Choice Models for Mining Stakeholder Analysis

This research sought to facilitate improved stakeholder analysis in mining by providing further insights into the preferences of local community members using discrete choice theory. While recent research has demonstrated the usefulness of discrete choice theory in mining stakeholder analysis, no previous work has examined which discrete choice model (DCM) is most suitable. This paper provides a research note on a case study in a mining community that was performed to compare three DCMs. After a thorough examination of the benefits and deficiencies of all models, this study concludes that the conditional logit model stratified by questions is the most useful DCM for mining stakeholder analysis. The recommendation is based on the usefulness and accuracy (ability to match the survey data) of this model

An Empirical Comparison of Discrete Choice Models for Mining Stakeholder Analysis

This research sought to facilitate improved stakeholder analysis in mining by providing further insights into the preferences of local community members using discrete choice theory. While recent research has demonstrated the usefulness of discrete choice theory in mining stakeholder analysis, no previous work has examined which discrete choice model (DCM) is most suitable. This paper provides a research note on a case study in a mining community that was performed to compare three DCMs. After a thorough examination of the benefits and deficiencies of all models, this study concludes that the conditional logit model stratified by questions is the most useful DCM for mining stakeholder analysis. The recommendation is based on the usefulness and accuracy (ability to match the survey data) of this model

Structural Characteristics of Aerobic Granular Sludge and Factors That Influence Its Stability: A Mini Review

Current extensive research on aerobic granular sludge (AGS) largely focuses on improving its microbial biodiversity, settlement behavior, nitrogen and phosphorus removal efficiency, and shock load resistance. Great challenges that have to be faced are the bottleneck of slow-speed granulation and easy disintegration after granulation, which are key to the extended application of AGS technology. In the present review, the typical morphological structures of AGS are firstly summarized as well as the granulation model hypotheses, and then, we analyze the dominant microflora and their spatial distribution features. The influencing factors on particle structure stability are discussed thereafter on a macro and micro scale. Prospects and future research trends are also discussed based on the current study results for AGS technology

New approach for bias correction and stochastic downscaling of future projections for daily mean temperatures to a high-resolution grid

In applications of climate information, coarse-resolution climate projections commonly need to be downscaled to a finer grid. One challenge of this requirement is the modeling of subgrid variability and the spatial and temporal dependence at the finer scale. Here, a postprocessing procedure for temperature projections is proposed that addresses this challenge. The procedure employs statistical bias correction and stochastic downscaling in two steps. In the first step, errors that are related to spatial and temporal features of the first two moments of the temperature distribution at model scale are identified and corrected. Second, residual space–time dependence at the finer scale is analyzed using a statistical model, from which realizations are generated and then combined with an appropriate climate change signal to form the downscaled projection fields. Using a high-resolution observational gridded data product, the proposed approach is applied in a case study in which projections of two regional climate models from the Coordinated Downscaling Experiment–European Domain (EURO-CORDEX) ensemble are bias corrected and downscaled to a 1 km × 1 km grid in the Trøndelag area of Norway. A cross-validation study shows that the proposed procedure generates results that better reflect the marginal distributional properties of the data product and have better consistency in space and time when compared with empirical quantile mapping

Obesity-induced inflammatory miR-133a mediates apoptosis of granulosa cells and causes abnormal folliculogenesis

Obesity has been reported to promote disordered folliculogenesis, but the exact molecular mechanisms are still not fully understood. In this study, we find that miR-133a is involved in obesity-induced follicular development disorder. After feeding with a high-fat diet (HFD) and fructose water for nine weeks, the mouse body weight is significantly increased, accompanied by an inflammatory state and increased expression of miR-133a in the adipose tissues and ovaries as well as accelerated follicle depletion. Although miR-133a is increased in the fat and ovaries of HFD mice, the increased miR-133a in the HFD ovaries is not derived from exosome transferred from obese adipose tissues but is synthesized by ovarian follicular cells in response to HFD-induced inflammation. In vivo experiments show that intrabursal injection of miR-133a agomir induces a decrease in primordial follicles and an increase in antral follicles and atretic follicles, which is similar to HFD-induced abnormal folliculogenesis. Overexpression of miR-133a modestly promotes granulosa cell apoptosis by balancing the expression of anti-apoptotic proteins such as C1QL1 and XIAP and pro-apoptotic proteins such as PTEN. Overall, this study reveals the function of miR-133a in obesity-induced ovarian folliculogenesis dysfunction and sheds light on the etiology of female reproductive disorders