48 research outputs found
Estrategia de posicionamiento para el turismo chino en AragĂłn
En vista a la creciente importancia del turismo emisor chino a nivel mundial, y queriendo realizar un estudios que sirva como base para mejorar la competitividad de la oferta turĂstica de AragĂłn centrado en el turismo chino, presente trabajo pretende analizar el perfil tĂpico del turista chino internacional, mediante la revisiĂłn de documentos bibliográficos, recopilaciĂłn y análisis de datos estadĂsticos, además de conocer el interĂ©s del turista chino sobre los recursos y productos turĂsticos actuales de AragĂłn mediante el diseño de una encuesta especializada. Y en funciĂłn de ello, se procederá a proponer una serie de estrategias para el posicionamiento, desarrollo y fidelizaciĂłn del mercado chino en AragĂłn.<br /
Magnetic field induced discontinuous spin reorientation in ErFeO3 single crystal
The spin reorientation of ErFeO3 that spontaneously occurs at low temperature has been previously determined to be a process involving the continuous rotation of Fe3Ăľ spins. In this work, the dynamic process of spin reorientation in ErFeO3 single crystal has been investigated by AC susceptibility measurements at various frequencies and static magnetic fields. Interestingly, two completely discontinuous steps are induced by a relatively large static magnetic field due to the variation in the magnetic anisotropy during this process. It provides deeper insights into the intriguing magnetic exchange interactions which dominate the sophisticated magnetic phase transitions in the orthoferrite systems
Magnetic field induced discontinuous spin reorientation in ErFeO 3
The spin reorientation of ErFeO3 that spontaneously occurs at low temperature has been previously determined to be a process involving the continuous rotation of Fe3Ăľ spins. In this work, the dynamic process of spin reorientation in ErFeO3 single crystal has been investigated by AC susceptibility measurements at various frequencies and static magnetic fields. Interestingly, two completely discontinuous steps are induced by a relatively large static magnetic field due to the variation in the magnetic anisotropy during this process. It provides deeper insights into the intriguing magnetic exchange interactions which dominate the sophisticated magnetic phase transitions in the orthoferrite systems
Ultraviolet photochemistry of ethane:implications for the atmospheric chemistry of the gas giants
Chemical processing in the stratospheres of the gas giants is driven by incident vacuum ultraviolet (VUV) light. Ethane is an important constituent in the atmospheres of the gas giants in our solar system. The present work describes translational spectroscopy studies of the VUV photochemistry of ethane using tuneable radiation in the wavelength range 112 ≤ λ ≤ 126 nm from a free electron laser and event-triggered, fast-framing, multi-mass imaging detection methods. Contributions from at least five primary photofragmentation pathways yielding CH(2), CH(3) and/or H atom products are demonstrated and interpreted in terms of unimolecular decay following rapid non-adiabatic coupling to the ground state potential energy surface. These data serve to highlight parallels with methane photochemistry and limitations in contemporary models of the photoinduced stratospheric chemistry of the gas giants. The work identifies additional photochemical reactions that require incorporation into next generation extraterrestrial atmospheric chemistry models which should help rationalise hitherto unexplained aspects of the atmospheric ethane/acetylene ratios revealed by the Cassini–Huygens fly-by of Jupiter
Magnetic structure and Ising-like antiferromagnetism in the bilayer triangular lattice compound NdZnPO
The complex interplay of spin frustration and quantum fluctuations in
low-dimensional quantum materials leads to a variety of intriguing phenomena.
This research focuses on a detailed analysis of the magnetic behavior exhibited
by NdZnPO, a bilayer spin-1/2 triangular lattice antiferromagnet. The
investigation employs magnetization, specific heat, and powder neutron
scattering measurements. At zero field, a long-range magnetic order is observed
at . Powder neutron diffraction experiments show the
Ising-like magnetic moments along the -axis, revealing a stripe-like
magnetic structure with three equivalent magnetic propagation vectors.
Application of a magnetic field along the -axis suppresses the
antiferromagnetic order, leading to a fully polarized ferromagnetic state above
. This transition is accompanied by notable enhancements
in the nuclear Schottky contribution. Moreover, the absence of spin frustration
and expected field-induced plateau-like phases are remarkable observations.
Detailed calculations of magnetic dipolar interactions revealed complex
couplings reminiscent of a honeycomb lattice, suggesting the potential
emergence of Kitaev-like physics within this system. This comprehensive study
of the magnetic properties of NdZnPO highlights unresolved intricacies,
underscoring the imperative for further exploration to unveil the underlying
governing mechanisms.Comment: 11 pages, 6 figure
Polyethyleneimine-coated MXene quantum dots improve cotton tolerance to Verticillium dahliae by maintaining ROS homeostasis
Verticillium dahliae is a soil-borne hemibiotrophic fungal pathogen that threatens cotton production worldwide. In this study, we assemble the genomes of two V. dahliae isolates: the more virulence and defoliating isolate V991 and nondefoliating isolate 1cd3-2. Transcriptome and comparative genomics analyses show that genes associated with pathogen virulence are mostly induced at the late stage of infection (Stage II), accompanied by a burst of reactive oxygen species (ROS), with upregulation of more genes involved in defense response in cotton. We identify the V991-specific virulence gene SP3 that is highly expressed during the infection Stage II. V. dahliae SP3 knock-out strain shows attenuated virulence and triggers less ROS production in cotton plants. To control the disease, we employ polyethyleneimine-coated MXene quantum dots (PEI-MQDs) that possess the ability to remove ROS. Cotton seedlings treated with PEI-MQDs are capable of maintaining ROS homeostasis with enhanced peroxidase, catalase, and glutathione peroxidase activities and exhibit improved tolerance to V. dahliae. These results suggest that V. dahliae trigger ROS production to promote infection and scavenging ROS is an effective way to manage this disease. This study reveals a virulence mechanism of V. dahliae and provides a means for V. dahliae resistance that benefits cotton production
Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC
Pancreatic ductal adenocarcinoma (PDAC) is considered the third leading cause of cancer mortality in the western world, offering advanced stage patients with few viable treatment options. Consequently, there remains an urgent unmet need to develop novel therapeutic strategies that can effectively inhibit pro-oncogenic molecular targets underpinning PDACs pathogenesis and progression. One such target is c-RAF, a downstream effector of RAS that is considered essential for the oncogenic growth and survival of mutant RAS-driven cancers (including KRASMT PDAC). Herein, we demonstrate how a novel cell-penetrating peptide disruptor (DRx-170) of the c-RAF–PDE8A protein–protein interaction (PPI) represents a differentiated approach to exploiting the c-RAF–cAMP/PKA signaling axes and treating KRAS–c-RAF dependent PDAC. Through disrupting the c-RAF–PDE8A protein complex, DRx-170 promotes the inactivation of c-RAF through an allosteric mechanism, dependent upon inactivating PKA phosphorylation. DRx-170 inhibits cell proliferation, adhesion and migration of a KRASMT PDAC cell line (PANC1), independent of ERK1/2 activity. Moreover, combining DRx-170 with afatinib significantly enhances PANC1 growth inhibition in both 2D and 3D cellular models. DRx-170 sensitivity appears to correlate with c-RAF dependency. This proof-of-concept study supports the development of DRx-170 as a novel and differentiated strategy for targeting c-RAF activity in KRAS–c-RAF dependent PDAC
Hydroxyl super rotors from vacuum ultraviolet photodissociation of water
Free electron lasers provide a state-of-the-art tool to investigate the photochemistry of water. Here, the authors show that highly rotationally excited hydroxyl radicals, so-called “super rotors” existing above the bond dissociation energy, are observed from the photodissociation of water, which may have implications for understanding the interstellar medium